1E96
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![BU of 1e96 by Molmil](/molmil-images/mine/1e96) | Structure of the Rac/p67phox complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... | Authors: | Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. | Deposit date: | 2000-10-10 | Release date: | 2000-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol.Cell, 6, 2000
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6TH0
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![BU of 6th0 by Molmil](/molmil-images/mine/6th0) | Crystal structure of Arabidopsis thaliana NAA60 in complex with acetyl-CoA | Descriptor: | ACETYL COENZYME *A, Acyl-CoA N-acyltransferases (NAT) superfamily protein | Authors: | Layer, D, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2019-11-18 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response. New Phytol., 228, 2020
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5TKY
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![BU of 5tky by Molmil](/molmil-images/mine/5tky) | Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein | Authors: | Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I. | Deposit date: | 2016-10-10 | Release date: | 2016-11-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun, 7, 2016
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2JPP
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![BU of 2jpp by Molmil](/molmil-images/mine/2jpp) | Structural basis of RsmA/CsrA RNA recognition: Structure of RsmE bound to the Shine-Dalgarno sequence of hcnA mRNA | Descriptor: | RNA (5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*CP*GP*GP*AP*UP*GP*AP*AP*GP*CP*CP*C)-3'), Translational repressor | Authors: | Schubert, M, Lapouge, K, Duss, O, Oberstrass, F.C, Jelesarov, I, Haas, D, Allain, F.H.-T. | Deposit date: | 2007-05-21 | Release date: | 2007-08-21 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA Nat.Struct.Mol.Biol., 14, 2007
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1OV3
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![BU of 1ov3 by Molmil](/molmil-images/mine/1ov3) | Structure of the p22phox-p47phox complex | Descriptor: | Flavocytochrome b558 alpha polypeptide, Neutrophil cytosol factor 1 | Authors: | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | Deposit date: | 2003-03-25 | Release date: | 2003-05-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis of phosphorylation-induced activation of the NADPH oxidase Cell(Cambridge,Mass.), 113, 2003
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1NG2
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![BU of 1ng2 by Molmil](/molmil-images/mine/1ng2) | Structure of autoinhibited p47phox | Descriptor: | Neutrophil cytosolic factor 1 | Authors: | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | Deposit date: | 2002-12-16 | Release date: | 2003-05-20 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular basis of phosphorylation-induced activation of the NADPH oxidase Cell(Cambridge,Mass.), 113, 2003
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6Y31
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![BU of 6y31 by Molmil](/molmil-images/mine/6y31) | NG domain of human SRP54 T117 deletion mutant | Descriptor: | Signal recognition particle 54 kDa protein | Authors: | Juaire, K.D, Lapouge, K, Becker, M.M.M, Kotova, I, Haas, M, Carapito, R, Wild, K, Bahram, S, Sinning, I. | Deposit date: | 2020-02-17 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (4.001 Å) | Cite: | Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia. Structure, 29, 2021
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6SR6
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![BU of 6sr6 by Molmil](/molmil-images/mine/6sr6) | Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | Authors: | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | Deposit date: | 2019-09-05 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb. Nat Commun, 11, 2020
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6TGX
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![BU of 6tgx by Molmil](/molmil-images/mine/6tgx) | Crystal structure of Arabidopsis thaliana NAA60 in complex with a bisubstrate analogue | Descriptor: | Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA | Authors: | Layer, D, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2019-11-18 | Release date: | 2020-06-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response. New Phytol., 228, 2020
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6Z00
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![BU of 6z00 by Molmil](/molmil-images/mine/6z00) | Arabidopsis thaliana Naa50 in complex with bisubstrate analogue CoA-Ac-MVNAL | Descriptor: | Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA-LEU | Authors: | Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2020-05-07 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure, 29, 2021
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6YZZ
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![BU of 6yzz by Molmil](/molmil-images/mine/6yzz) | Arabidopsis thaliana Naa50 in complex with AcCoA | Descriptor: | ACETYL COENZYME *A, N-alpha-acetyltransferase 50 | Authors: | Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2020-05-07 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure, 29, 2021
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5MB9
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![BU of 5mb9 by Molmil](/molmil-images/mine/5mb9) | Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Gumiero, A, Weyer, F.A, Valentin Gese, G, Lapouge, K, Sinning, I. | Deposit date: | 2016-11-07 | Release date: | 2016-12-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex. Nat. Struct. Mol. Biol., 24, 2017
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5NIY
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![BU of 5niy by Molmil](/molmil-images/mine/5niy) | Signal recognition particle-docking protein FtsY | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY | Authors: | Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I. | Deposit date: | 2017-03-27 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane. Structure, 26, 2018
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7OLD
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![BU of 7old by Molmil](/molmil-images/mine/7old) | Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OLC
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![BU of 7olc by Molmil](/molmil-images/mine/7olc) | Thermophilic eukaryotic 80S ribosome at idle POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OJU
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![BU of 7oju by Molmil](/molmil-images/mine/7oju) | Chaetomium thermophilum Naa50 GNAT-domain in complex with bisubstrate analogue CoA-Ac-MVNAL | Descriptor: | CARBOXYMETHYL COENZYME *A, GLYCEROL, HEXAETHYLENE GLYCOL, ... | Authors: | Weidenhausen, J, Kopp, J, Sinning, I. | Deposit date: | 2021-05-17 | Release date: | 2022-09-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Extended N-Terminal Acetyltransferase Naa50 in Filamentous Fungi Adds to Naa50 Diversity. Int J Mol Sci, 23, 2022
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7Z3N
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![BU of 7z3n by Molmil](/molmil-images/mine/7z3n) | Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-1 conformation | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2022-03-02 | Release date: | 2023-04-12 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nat.Struct.Mol.Biol., 30, 2023
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7Z3O
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![BU of 7z3o by Molmil](/molmil-images/mine/7z3o) | Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-2 conformation | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2022-03-02 | Release date: | 2023-04-12 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nat.Struct.Mol.Biol., 30, 2023
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6SXO
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![BU of 6sxo by Molmil](/molmil-images/mine/6sxo) | Cryo-EM structure of the human Ebp1-ribosome complex | Descriptor: | 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ... | Authors: | Wild, K, Aleksic, M, Pfeffer, M, Sinning, I. | Deposit date: | 2019-09-26 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments. Nat Commun, 11, 2020
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7BJS
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![BU of 7bjs by Molmil](/molmil-images/mine/7bjs) | Crystal structure of Khc/atypical Tm1 complex | Descriptor: | Kinesin heavy chain, SD21996p | Authors: | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | Deposit date: | 2021-01-14 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex. Genes Dev., 35, 2021
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7BJN
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![BU of 7bjn by Molmil](/molmil-images/mine/7bjn) | Crystal structure of atypical Tm1 (Tm1-I/C), residues 270-334 | Descriptor: | SD21996p | Authors: | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | Deposit date: | 2021-01-14 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex. Genes Dev., 35, 2021
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7BJG
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![BU of 7bjg by Molmil](/molmil-images/mine/7bjg) | Crystal structure of atypical Tm1 (Tm1-I/C), residues 262-363 | Descriptor: | SD21996p | Authors: | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | Deposit date: | 2021-01-14 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex. Genes Dev., 35, 2021
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6Y32
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![BU of 6y32 by Molmil](/molmil-images/mine/6y32) | Structure of the GTPase heterodimer of human SRP54 and SRalpha | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SULFATE ION, ... | Authors: | Juaire, K.D, Becker, M.M.M, Wild, K, Sinning, I. | Deposit date: | 2020-02-17 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia. Structure, 29, 2021
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6Y2Z
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![BU of 6y2z by Molmil](/molmil-images/mine/6y2z) | NG domain of human SRP54 | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, Signal recognition particle 54 kDa protein | Authors: | Juaire, K.D, Wild, K, Sinning, I. | Deposit date: | 2020-02-17 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia. Structure, 29, 2021
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8PJB
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![BU of 8pjb by Molmil](/molmil-images/mine/8pjb) | |