8PAY
| Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 2. | 分子名称: | ACE-GLN-ALC-GLC-LEU-PHE, Beta sliding clamp, GLYCEROL, ... | 著者 | Compain, G, Monsarrat, C, Blagojevic, J, Brillet, K, Dumas, P, Hammann, P, Kuhn, L, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Burnouf, D, wagner, J, Guichard, G. | 登録日 | 2023-06-08 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp. Jacs Au, 4, 2024
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8PAT
| Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 3. | 分子名称: | ACE-GLN-ALC-GLX-LEU-PHE, Beta sliding clamp | 著者 | Compain, G, Monsarrat, C, Blagojevic, J, Brillet, K, Dumas, P, Hammann, P, Kuhn, L, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Burnouf, D, Guichard, G. | 登録日 | 2023-06-08 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp. Jacs Au, 4, 2024
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5A5U
| Structure of mammalian eIF3 in the context of the 43S preinitiation complex | 分子名称: | EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I | 著者 | des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y. | 登録日 | 2015-06-21 | 公開日 | 2015-09-09 | 最終更新日 | 2018-10-03 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex. Nature, 525, 2015
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5A5T
| Structure of mammalian eIF3 in the context of the 43S preinitiation complex | 分子名称: | EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E, ... | 著者 | des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y. | 登録日 | 2015-06-21 | 公開日 | 2015-09-09 | 最終更新日 | 2018-10-03 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex. Nature, 525, 2015
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5K1H
| eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation. | 分子名称: | Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-18 | 公開日 | 2016-07-13 | 最終更新日 | 2018-01-31 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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5K0Y
| m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-17 | 公開日 | 2016-07-13 | 最終更新日 | 2018-04-18 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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7ASK
| 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kDDX60 | 著者 | Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. | 登録日 | 2020-10-27 | 公開日 | 2021-04-14 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
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7ASE
| 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase | 分子名称: | 18S, 40S ribosomal protein S10, putative, ... | 著者 | Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. | 登録日 | 2020-10-27 | 公開日 | 2021-04-14 | 最終更新日 | 2021-04-21 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
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7PKT
| Large subunit of the Chlamydomonas reinhardtii mitoribosome | 分子名称: | 50S ribosomal protein L20, 50S ribosomal protein L9, chloroplastic, ... | 著者 | Waltz, F, Soufari, H, Hashem, Y. | 登録日 | 2021-08-26 | 公開日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | How to build a ribosome from RNA fragments in Chlamydomonas mitochondria. Nat Commun, 12, 2021
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7PKQ
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6YAN
| Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6YAL
| Mammalian 48S late-stage initiation complex with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6YAM
| Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6Z8A
| Outer membrane FoxA in complex with nocardamine | 分子名称: | (8E)-6,17,28-trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacont-8-ene-2,5,13,16,24,27-hexone, DIMETHYL SULFOXIDE, FE (III) ION, ... | 著者 | Josts, I, Tidow, H. | 登録日 | 2020-06-02 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Nocardamine-Dependent Iron Uptake in Pseudomonas aeruginosa : Exclusive Involvement of the FoxA Outer Membrane Transporter. Acs Chem.Biol., 15, 2020
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7ZKY
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7AOR
| mt-SSU from Trypanosoma cruzi in complex with mt-IF-3. | 分子名称: | 30S Ribosomal protein S17-like protein, AKAP7_NLS domain-containing protein, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | 登録日 | 2020-10-15 | 公開日 | 2021-04-28 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7AIH
| The Large subunit of the Kinetoplastid mitochondrial ribosome | 分子名称: | 50S ribosomal protein L13-like protein, C2H2-type domain-containing protein, L51_S25_CI-B8 domain-containing protein, ... | 著者 | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | 登録日 | 2020-09-27 | 公開日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7AM2
| Intermediate assembly of the Large subunit from Leishmania major mitochondrial ribosome | 分子名称: | 50S ribosomal protein L13-like protein, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | 著者 | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | 登録日 | 2020-10-07 | 公開日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7A24
| Assembly intermediate of the plant mitochondrial complex I | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | 著者 | Soufari, H, Waltz, F, Hashem, Y. | 登録日 | 2020-08-16 | 公開日 | 2020-10-28 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM. Nat Commun, 11, 2020
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7ANE
| Leishmania Major mitochondrial ribosome | 分子名称: | 30S Ribosomal protein S17-like protein, 50S ribosomal protein L13-like protein, AKAP7_NLS domain-containing protein, ... | 著者 | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | 登録日 | 2020-10-11 | 公開日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7A23
| Plant mitochondrial respiratory complex I | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | 著者 | Soufari, H, Waltz, F, Hashem, Y. | 登録日 | 2020-08-15 | 公開日 | 2020-10-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM. Nat Commun, 11, 2020
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8RDX
| PGGtase I in complex with probe BAY-6092 | 分子名称: | (5~{R})-5-(2-methoxyphenyl)-9-[(2~{R})-3,3,3-tris(fluoranyl)-2-methoxy-2-phenyl-propanoyl]-3,9-diazaspiro[5.5]undecan-2-one, CHLORIDE ION, DIPHOSPHATE, ... | 著者 | Steuber, H. | 登録日 | 2023-12-08 | 公開日 | 2024-02-14 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (3.67 Å) | 主引用文献 | Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol, 2024
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