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5XE4
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BU of 5xe4 by Molmil
NMR solution structure of the aromatic mutant H43W H67F cytochrome b5
Descriptor: Cytochrome b5
Authors:Balakrishnan, S, Sarma, S.P.
Deposit date:2017-03-31
Release date:2018-02-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Engineering Aromatic-Aromatic Interactions To Nucleate Folding in Intrinsically Disordered Regions of Proteins
Biochemistry, 56, 2017
5XEE
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BU of 5xee by Molmil
NMR solution structure of the aromatic mutant H43F H67F cytochrome b5
Descriptor: Cytochrome b5
Authors:Balakrishnan, S, Sarma, S.P.
Deposit date:2017-04-04
Release date:2018-02-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Engineering Aromatic-Aromatic Interactions To Nucleate Folding in Intrinsically Disordered Regions of Proteins
Biochemistry, 56, 2017
8U5Y
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BU of 8u5y by Molmil
human RADX trimer bound to ssDNA
Descriptor: DNA (25-MER), RPA-related protein RADX
Authors:Balakrishnan, S, Chazin, W.J.
Deposit date:2023-09-13
Release date:2023-10-11
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structure of RADX and mechanism for regulation of RAD51 nucleofilaments.
Biorxiv, 2023
8U61
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BU of 8u61 by Molmil
Human RADX tetramer bound to ssDNA
Descriptor: RPA-related protein RADX, dT25 DNA (25-MER)
Authors:Balakrishnan, S, Chazin, W.J.
Deposit date:2023-09-13
Release date:2024-01-31
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of RADX and mechanism for regulation of RAD51 nucleofilaments.
Proc.Natl.Acad.Sci.USA, 121, 2024
4HON
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BU of 4hon by Molmil
Crystal structure of human JMJD2D/KDM4D in complex with an H3K9me3 peptide and 2-oxoglutarate
Descriptor: 1,3-PROPANDIOL, 2-OXOGLUTARIC ACID, Histone H3 Peptide, ...
Authors:Krishnan, S, Trievel, R.C.
Deposit date:2012-10-22
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases.
Structure, 21, 2013
4HOO
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BU of 4hoo by Molmil
Crystal structure of human JMJD2D/KDM4D apoenzyme
Descriptor: ACETATE ION, Lysine-specific demethylase 4D, NICKEL (II) ION, ...
Authors:Krishnan, S, Trievel, R.C.
Deposit date:2012-10-22
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases.
Structure, 21, 2013
8TQS
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BU of 8tqs by Molmil
Complex of human thrombin (S195A) bound to a bivalent inhibitor comprised of DNA Aptamer HD22 conjugated to Dabigatran with a linker.
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ...
Authors:Krishnaswamy, S, Kumar, S.
Deposit date:2023-08-08
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.207 Å)
Cite:Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors.
Nat Commun, 15, 2024
5VOF
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BU of 5vof by Molmil
DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban
Descriptor: 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, CALCIUM ION, Coagulation factor X, ...
Authors:Krishnaswamy, S, Kumar, S.
Deposit date:2017-05-02
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.
Nat. Biotechnol., 36, 2018
6OEI
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BU of 6oei by Molmil
Yeast Spc42 N-terminal coiled-coil fused to PDB: 3K2N
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Spindle pole body component SPC42,Sigma-54-dependent transcriptional regulator
Authors:Drennan, A.C, Krishna, S, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jaspersen, S.L, Rayment, I.
Deposit date:2019-03-27
Release date:2019-04-24
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication.
Mol.Biol.Cell, 30, 2019
6OD2
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BU of 6od2 by Molmil
Yeast Spc42 C-terminal Antiparallel Coiled-Coil
Descriptor: Spindle pole body component SPC42
Authors:Drennan, A.C, Krishna, S, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jaspersen, S.L, Rayment, I.
Deposit date:2019-03-25
Release date:2019-04-24
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.435 Å)
Cite:Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication.
Mol.Biol.Cell, 30, 2019
4PTN
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BU of 4ptn by Molmil
Crystal Structure of YagE, a KDG aldolase protein in complex with Magnesium cation coordinated L-glyceraldehyde
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, L-glyceraldehyde, ...
Authors:Manoj Kumar, P, Baskar, V, Manicka, S, Krishnaswamy, S.
Deposit date:2014-03-11
Release date:2014-12-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12.
Proteins, 71, 2008
4U4M
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BU of 4u4m by Molmil
Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate
Descriptor: 1,2-ETHANEDIOL, PYRUVIC ACID, UREA, ...
Authors:Manoj Kumar, P, Bhaskar, V, Manicka, S, Krishnaswamy, S.
Deposit date:2014-07-24
Release date:2015-07-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate
To be published
4OE7
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BU of 4oe7 by Molmil
Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
Descriptor: (4R)-4-hydroxy-2,5-dioxopentanoic acid, (4S)-4-hydroxy-2,5-dioxopentanoic acid, 1,2-ETHANEDIOL, ...
Authors:Manoj Kumar, P, Baskar, V, Manicka, S, Krishnaswamy, S.
Deposit date:2014-01-12
Release date:2014-12-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
To be Published
4ONV
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BU of 4onv by Molmil
Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate
Descriptor: 1,2-ETHANEDIOL, 2-KETO-3-DEOXYGLUCONATE, GLYCEROL, ...
Authors:Manoj Kumar, P, Bhaskar, V, Manicka, S, Krishnaswamy, S.
Deposit date:2014-01-29
Release date:2015-01-14
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate
To be Published
3NEV
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BU of 3nev by Molmil
Crystal structure of YagE, a prophage protein from E. coli K12 in complex with KDGal
Descriptor: 1,2-ETHANEDIOL, 3-DEOXY-D-LYXO-HEXONIC ACID, Uncharacterized protein yagE
Authors:Bhaskar, V, Kumar, P.M, Manicka, S, Krishnaswamy, S.
Deposit date:2010-06-09
Release date:2011-04-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis.
Proteins, 79, 2011
2V9D
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BU of 2v9d by Molmil
Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12
Descriptor: YAGE
Authors:Manicka, S, Peleg, Y, Unger, T, Albeck, S, Dym, O, Greenblatt, H.M, Bourenkov, G, Lamzin, V, Krishnaswamy, S, Sussman, J.L.
Deposit date:2007-08-23
Release date:2008-03-04
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Yage, a Putative Dhdps Like Protein from Escherichia Coli K12.
Proteins: Struct., Funct., Bioinf., 71, 2008
3N2X
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BU of 3n2x by Molmil
Crystal structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12 in complex with pyruvate
Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein yagE
Authors:Bhaskar, V, Kumar, P.M, Manicka, S, Krishnaswamy, S.
Deposit date:2010-05-19
Release date:2011-04-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis.
Proteins, 79, 2011
2V8Z
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BU of 2v8z by Molmil
Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12
Descriptor: YAGE
Authors:Manicka, S, Peleg, Y, Unger, T, Albeck, S, Dym, O, Greenblatt, H.M, Bourenkov, G, Lamzin, V, Krishnaswamy, S, Sussman, J.L.
Deposit date:2007-08-16
Release date:2008-03-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Yage, a Putative Dhdps Like Protein from Escherichia Coli K12.
Proteins: Struct., Funct., Bioinf., 71, 2008
3JTC
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BU of 3jtc by Molmil
Importance of Mg2+ in the Ca2+-Dependent Folding of the gamma-Carboxyglutamic Acid Domains of Vitamin K-Dependent clotting and anticlotting Proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endothelial protein C receptor, ...
Authors:Bajaj, S.P, Vadivel, K, Agah, S, Cascio, D, Krishnaswamy, S, Esmon, C, Padmanabhan, K.
Deposit date:2009-09-11
Release date:2011-04-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Studies of gamma-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium.
J.Mol.Biol., 425, 2013
3NSG
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BU of 3nsg by Molmil
Crystal Structure of OmpF, an Outer Membrane Protein from Salmonella typhi
Descriptor: CITRATE ANION, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Balasubramaniam, D, Arockiasamy, A, Sharma, A, Krishnaswamy, S.
Deposit date:2010-07-01
Release date:2011-07-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Asymmetric pore occupancy in crystal structure of OmpF porin from Salmonella typhi
J.Struct.Biol., 178, 2012
2RMU
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BU of 2rmu by Molmil
THREE-DIMENSIONAL STRUCTURES OF DRUG-RESISTANT MUTANTS OF HUMAN RHINOVIRUS 14
Descriptor: HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J, Krishnaswamy, S, Kremer, M.J, Oliveira, M.A, Rossmann, M.G, Heinz, B.A, Rueckert, R.R, Dutko, F.J, Mckinlay, M.A.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-dimensional structures of drug-resistant mutants of human rhinovirus 14.
J.Mol.Biol., 207, 1989
8EPC
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BU of 8epc by Molmil
Crystal structure of human coagulation factor IXa (S195A), apo-form
Descriptor: CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain
Authors:Kolyadko, V.N, Krishnaswamy, S.
Deposit date:2022-10-05
Release date:2024-07-03
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Allosteric Control of Coagulation Factor IXa via Its Exosite II Regulates Blood Clotting
Proc.Natl.Acad.Sci.USA, 2024
8EPH
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BU of 8eph by Molmil
Crystal structure of human coagulation factor IXa (S195A), apo-form, DES-GLA
Descriptor: CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain, ...
Authors:Kolyadko, V.N, Krishnaswamy, S.
Deposit date:2022-10-05
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Allosteric Control of Coagulation Factor IXa via Its Exosite II Regulates Blood Clotting
Proc.Natl.Acad.Sci.USA, 2024
8EPK
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BU of 8epk by Molmil
Complex of anticoagulant RNA aptamer and human coagulation factor IXa (S195A)
Descriptor: CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain, ...
Authors:Kolyadko, V.N, Krishnaswamy, S.
Deposit date:2022-10-05
Release date:2024-07-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Allosteric Control of Coagulation Factor IXa via Its Exosite II Regulates Blood Clotting
Proc.Natl.Acad.Sci.USA, 2024
2J4U
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BU of 2j4u by Molmil
E.coli OmpC - camel Lactoferrin complex
Descriptor: LACTOTRANSFERRIN, OUTER MEMBRANE PROTEIN C PRECURSOR
Authors:Baalaji, S, Acharya, R.K, Singh, T.P, Krishnaswamy, S.
Deposit date:2006-09-06
Release date:2007-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Crystal Structure of the Membrane Protein Ompc Complex with Antibacterial Lactoferrin
To be Published

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