5ACA
 
 | | Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design | | 分子名称: | VP1, VP2, VP3, ... | | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | | 登録日 | 2015-08-14 | | 公開日 | 2015-09-23 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design
Nat.Struct.Mol.Biol., 22, 2015
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5AC9
 | | Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design | | 分子名称: | VP1, VP2, VP3, ... | | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, PerezMartin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | | 登録日 | 2015-08-14 | | 公開日 | 2015-09-23 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design
Nat.Struct.Mol.Biol., 22, 2015
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5D8A
 | | Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093F empty capsid | | 分子名称: | VP1, VP2, VP3, ... | | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | | 登録日 | 2015-08-16 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.
Nat.Struct.Mol.Biol., 22, 2015
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5DDJ
 | | Crystal structure of recombinant foot-and-mouth-disease virus O1M-S2093Y empty capsid | | 分子名称: | Foot and mouth disease virus, VP1, VP2, ... | | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | | 登録日 | 2015-08-25 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.
Nat.Struct.Mol.Biol., 22, 2015
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5NET
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5NEM
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5NEU
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5NE4
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5NED
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5NER
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5NEJ
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5OW6
 | | CryoEM structure of recombinant CMV particles with Tetanus-epitope | | 分子名称: | Capsid protein, VP2, VP3, ... | | 著者 | Kotecha, A, Stuart, D.I, Backmann, M. | | 登録日 | 2017-08-30 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy.
NPJ Vaccines, 2, 2017
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5OYI
 | | FMDV A10 dissociated pentamer | | 分子名称: | Genome polyprotein | | 著者 | Kotecha, A, Malik, N, Stuart, D.I. | | 登録日 | 2017-09-09 | | 公開日 | 2017-09-20 | | 最終更新日 | 2018-10-03 | | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | | 主引用文献 | Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.
PLoS Pathog., 13, 2017
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5OWX
 | | Inside-out FMDV A10 capsid | | 分子名称: | Genome polyprotein | | 著者 | Kotecha, A, Malik, N, Fry, E.E, Stuart, D.I. | | 登録日 | 2017-09-04 | | 公開日 | 2017-09-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.
PLoS Pathog., 13, 2017
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6XF8
 | | DLP 5 fold | | 分子名称: | Inner capsid protein lambda-1, Inner capsid protein sigma-2, Outer capsid protein mu-1, ... | | 著者 | Sutton, G, Sun, D.P, Fu, X.F, Kotecha, A, Hecksel, G.W, Clare, D.K, Zhang, P, Stuart, D, Boyce, M. | | 登録日 | 2020-06-15 | | 公開日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Assembly intermediates of orthoreovirus captured in the cell.
Nat Commun, 11, 2020
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3JB4
 | | Structure of Ljungan virus: insight into picornavirus packaging | | 分子名称: | VP0, VP1, VP3 | | 著者 | Zhu, L, Wang, X.X, Ren, J.S, Porta, C, Wenham, H, Ekstrom, J.-O, Panjwani, A, Knowles, N.J, Kotecha, A, Siebert, A, Lindberg, M, Fry, E.E, Rao, Z.H, Tuthill, T.J, Stuart, D.I. | | 登録日 | 2015-07-21 | | 公開日 | 2015-10-21 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of Ljungan virus provides insight into genome packaging of this picornavirus.
Nat Commun, 6, 2015
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7ZPP
 | | Cryo-EM structure of the MVV CSC intasome at 4.5A resolution | | 分子名称: | Integrase, vDNA, non-transferred strand, ... | | 著者 | Ballandras-Colas, A, Maskell, D, Pye, V.E, Locke, J, Swuec, S, Kotecha, A, Costa, A, Cherepanov, P. | | 登録日 | 2022-04-28 | | 公開日 | 2022-05-11 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | A supramolecular assembly mediates lentiviral DNA integration
Science, 355, 2017
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8BQW
 | | Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy | | 分子名称: | Alpha-synuclein, Unknown protein | | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | | 登録日 | 2023-01-18 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
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8BQV
 | | Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy | | 分子名称: | Alpha-synuclein, Unknown protein | | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | | 登録日 | 2023-01-18 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
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8CEB
 | | Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein | | 分子名称: | Alpha-synuclein | | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Sew, P.C, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | | 登録日 | 2023-02-01 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
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8CE7
 | | Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein | | 分子名称: | Alpha-synuclein | | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | | 登録日 | 2023-02-01 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
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4IV1
 | | Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B. | | 登録日 | 2013-01-22 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
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4IV3
 | | Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B. | | 登録日 | 2013-01-22 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
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7KJR
 | | Cryo-EM structure of SARS-CoV-2 ORF3a | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apolipoprotein A-I, ORF3a protein | | 著者 | Kern, D.M, Hoel, C.M, Kotecha, A, Brohawn, S.G. | | 登録日 | 2020-10-26 | | 公開日 | 2020-11-18 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | | 主引用文献 | Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
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6HUK
 | | CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with bicuculline and megabody Mb38. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-3, ... | | 著者 | Masiulis, S, Desai, R, Uchanski, T, Serna Martin, I, Laverty, D, Karia, D, Malinauskas, T, Jasenko, Z, Pardon, E, Kotecha, A, Steyaert, J, Miller, K.W, Aricescu, A.R. | | 登録日 | 2018-10-08 | | 公開日 | 2019-01-02 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | GABAAreceptor signalling mechanisms revealed by structural pharmacology.
Nature, 565, 2019
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