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6YIO
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BU of 6yio by Molmil
CRYSTAL STRUCTURE OF FAB RG6292 IN COMPLEX WITH CD25 ECD
Descriptor: FAB FRAGMENT HEAVY CHAIN, FAB FRGAMENT LIGHT CHAIN, Interleukin-2 receptor subunit alpha
Authors:Benz, J, Koll, H, Leibrock, L.
Deposit date:2020-04-01
Release date:2020-11-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:CD25-T reg -depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.
Nat Cancer, 1, 2020
1YOM
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BU of 1yom by Molmil
Crystal structure of Src kinase domain in complex with Purvalanol A
Descriptor: 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, Proto-oncogene tyrosine-protein kinase Src
Authors:Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A.
Deposit date:2005-01-27
Release date:2006-01-27
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
1YOJ
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BU of 1yoj by Molmil
Crystal structure of Src kinase domain
Descriptor: proto-oncogene tyrosine-protein kinase SRC
Authors:Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A.
Deposit date:2005-01-27
Release date:2006-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
1YOL
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BU of 1yol by Molmil
Crystal structure of Src kinase domain in complex with CGP77675
Descriptor: 1-{4-[4-AMINO-5-(3-METHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL]BENZYL}PIPERIDIN-4-OL, Proto-oncogene tyrosine-protein kinase Src
Authors:Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A.
Deposit date:2005-01-27
Release date:2006-01-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
5MW2
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BU of 5mw2 by Molmil
CRYSTAL STRUCTURE OF BCL-6 BTB-domain with BI-3802
Descriptor: 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide, B-cell lymphoma 6 protein
Authors:Bader, G, Flotzinger, G, Weiss-Puxbaum, A, Zoephel, A.
Deposit date:2017-01-18
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
5MW6
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BU of 5mw6 by Molmil
Crystal structure of the BCL6 BTB-domain with compound 1
Descriptor: 5-chloranyl-~{N}-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-amine, B-cell lymphoma 6 protein
Authors:Davies, D.R, Kessler, D.
Deposit date:2017-01-18
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
5MWD
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BU of 5mwd by Molmil
Crystal structure of the BCL6 BTB-domain with compound 2
Descriptor: 5-[[5-chloranyl-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]amino]-1,3-dihydroindol-2-one, B-cell lymphoma 6 protein
Authors:Bader, G, Flotzinger, G, Weiss-Puxbaum, A, Zoephel, A.
Deposit date:2017-01-18
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
5UR6
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BU of 5ur6 by Molmil
PYR1 bound to the rationally designed agonist cyanabactin
Descriptor: Abscisic acid receptor PYR1, N-(4-cyano-3-cyclopropylphenyl)-1-(4-methylphenyl)methanesulfonamide, SULFATE ION
Authors:Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R.
Deposit date:2017-02-09
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration.
ACS Chem. Biol., 12, 2017
5UR5
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BU of 5ur5 by Molmil
PYR1 bound to the rationally designed agonist 4m
Descriptor: Abscisic acid receptor PYR1, GLYCEROL, N-(4-cyano-3-ethyl-5-methylphenyl)-1-(4-methylphenyl)methanesulfonamide, ...
Authors:Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R.
Deposit date:2017-02-09
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration.
ACS Chem. Biol., 12, 2017

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