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4JO7
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BU of 4jo7 by Molmil
Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry
Descriptor: Nucleoporin p54, Nucleoporin p58/p45
Authors:Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
Deposit date:2013-03-17
Release date:2014-09-17
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
2I5Z
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BU of 2i5z by Molmil
The crystal structure of OspA mutant
Descriptor: Outer surface protein A, TETRAETHYLENE GLYCOL
Authors:Makabe, K, Terechko, V, Koide, S.
Deposit date:2006-08-26
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet.
J.Mol.Biol., 368, 2007
5DC0
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BU of 5dc0 by Molmil
CRYSTAL STRUCTURE OF MONOBODY GG3/ABL1 SH2 DOMAIN COMPLEX
Descriptor: Fibronectin, Tyrosine-protein kinase ABL1
Authors:Wojcik, J.B, Grabe, G, Koide, S.
Deposit date:2015-08-22
Release date:2016-03-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
5E08
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BU of 5e08 by Molmil
Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment
Descriptor: Fab Heavy Chain, Fab Light Chain, RNA
Authors:Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A.
Deposit date:2015-09-28
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
J.Mol.Biol., 428, 2016
6CPG
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BU of 6cpg by Molmil
Structure of dephosphorylated Aurora A (122-403) in complex with inhibiting monobody and AT9283 in an inactive conformation
Descriptor: 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea, Aurora kinase A, Monobody
Authors:Otten, R, Kutter, S, Zorba, A, Padua, R.A.P, Koide, A, Koide, S, Kern, D.
Deposit date:2018-03-13
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dynamics of human protein kinase Aurora A linked to drug selectivity.
Elife, 7, 2018
6UX8
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BU of 6ux8 by Molmil
Structure of monobody 33 MLKL N-terminal domain complex
Descriptor: Mixed lineage kinase domain-like protein, Monobody, ZINC ION
Authors:Birkinshaw, R.W, Petrie, E.J, Murphy, J.M.
Deposit date:2019-11-07
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WU1
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BU of 6wu1 by Molmil
Structure of apo LaINDY
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU2
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BU of 6wu2 by Molmil
Structure of the LaINDY-malate complex
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WK8
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BU of 6wk8 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in complex with phenylguanidinium
Descriptor: 1-phenylguanidine, DECYL-BETA-D-MALTOPYRANOSIDE, Dodecyldimethylphosphine oxide, ...
Authors:Kermani, A.A, Stockbridge, R.B.
Deposit date:2020-04-15
Release date:2020-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020
6WTW
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BU of 6wtw by Molmil
Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate
Descriptor: DASS family sodium-coupled anion symporter
Authors:Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WK5
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BU of 6wk5 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters
Descriptor: L10 monobody, Multidrug resistance protein, SMR family
Authors:Kermani, A.A, Stockbridge, R.B.
Deposit date:2020-04-15
Release date:2020-10-28
Last modified:2020-12-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020
6WK9
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BU of 6wk9 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in complex with octylguanidinium
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, L10 monobody, Multidrug resistance protein, ...
Authors:Kermani, A.A, Stockbridge, R.B.
Deposit date:2020-04-15
Release date:2020-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020
6WU4
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BU of 6wu4 by Molmil
Structure of the LaINDY-alpha-ketoglutarate complex
Descriptor: DASS family sodium-coupled anion symporter
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WTX
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BU of 6wtx by Molmil
Structure of VcINDY in complex with terephthalate
Descriptor: DASS family sodium-coupled anion symporter, SODIUM ION, terephthalic acid
Authors:Sauer, D.B, Marden, J.J, Wang, D.N.
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU3
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BU of 6wu3 by Molmil
Structure of VcINDY-Na+ in amphipol
Descriptor: VcINDY
Authors:Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N.
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
4JEG
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BU of 4jeg by Molmil
Crystal Structure of Monobody CS1/SHP2 C-SH2 Domain Complex
Descriptor: Monobody CS1, Tyrosine-protein phosphatase non-receptor type 11
Authors:Sha, F, Koide, S.
Deposit date:2013-02-26
Release date:2013-08-28
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JMH
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BU of 4jmh by Molmil
Crystal structure of synthetic protein in complex with double pY peptide
Descriptor: Clamp Shc1_pY239/240, SHC-transforming protein 1
Authors:Yasui, N, Smith, L, Koide, S.
Deposit date:2013-03-14
Release date:2014-04-23
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.408 Å)
Cite:Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
4JE4
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BU of 4je4 by Molmil
Crystal Structure of Monobody NSa1/SHP2 N-SH2 Domain Complex
Descriptor: Monobody NSa1, Tyrosine-protein phosphatase non-receptor type 11
Authors:Sha, F, Koide, S.
Deposit date:2013-02-26
Release date:2013-08-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JMG
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BU of 4jmg by Molmil
Crystal structure of the synthetic protein in complex with pY peptide
Descriptor: Clamp Ptpn11_pY580, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 11
Authors:Yasui, N, Smith, L, Koide, S.
Deposit date:2013-03-14
Release date:2014-04-23
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.403 Å)
Cite:Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
2R8S
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BU of 2r8s by Molmil
High resolution structure of a specific synthetic FAB bound to P4-P6 RNA ribozyme domain
Descriptor: Fab heavy chain, Fab light chain, MAGNESIUM ION, ...
Authors:Ye, J.D, Tereshko, V, Sidhu, S.S, Koide, S, Kossiakoff, A.A, Piccirilli, J.A.
Deposit date:2007-09-11
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Synthetic antibodies for specific recognition and crystallization of structured RNA
Proc.Natl.Acad.Sci.Usa, 105, 2008
4HUN
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BU of 4hun by Molmil
MATE transporter NorM-NG in complex with R6G and monobody
Descriptor: Multidrug efflux protein, RHODAMINE 6G, protein B
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HUL
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BU of 4hul by Molmil
MATE transporter NorM-NG in complex with Cs+ and monobody
Descriptor: CESIUM ION, Multidrug efflux protein, Protein B
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.81 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HUK
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BU of 4huk by Molmil
MATE transporter NorM-NG in complex with TPP and monobody
Descriptor: Multidrug efflux protein, Protein B, TETRAPHENYLPHOSPHONIUM
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HUM
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BU of 4hum by Molmil
MATE transporter NorM-NG in complex with ethidium and monobody
Descriptor: ETHIDIUM, Multidrug efflux protein, Protein B
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
2OYB
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BU of 2oyb by Molmil
The crystal structure of OspA mutant
Descriptor: Outer surface protein A
Authors:Makabe, K, Biancalana, M, Terechko, V, Koide, S.
Deposit date:2007-02-21
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics
J.Mol.Biol., 383, 2008

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