6IME
 
 | | Rv2361c complex with substrate analogues | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, CARBONATE ION, ... | | 著者 | Ko, T.-P, Guo, R.-T, Chen, C.-C, Liu, W. | | 登録日 | 2018-10-22 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Substrate-analogue complex structure of Mycobacterium tuberculosis decaprenyl diphosphate synthase.
Acta Crystallogr.,Sect.F, 75, 2019
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1UAQ
 | | The crystal structure of yeast cytosine deaminase | | 分子名称: | DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, ZINC ION, cytosine deaminase | | 著者 | Ko, T.-P, Lin, J.-J, Hu, C.-Y, Hsu, Y.-H, Wang, A.H.-J, Liaw, S.-H. | | 登録日 | 2003-03-14 | | 公開日 | 2003-04-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution
J.Biol.Chem., 278, 2003
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7EBL
 | | Bacterial STING in complex with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), STING | | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | 登録日 | 2021-03-10 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Crystal structure and functional implication of bacterial STING.
Nat Commun, 13, 2022
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7EBD
 | | Bacterial STING in complex with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, TIR-like domain-containing protein | | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | 登録日 | 2021-03-09 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure and functional implication of bacterial STING.
Nat Commun, 13, 2022
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1DGR
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1DGW
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5GWW
 | | Structure of MoeN5-Sso7d fusion protein in complex with a permethylated substrate analogue | | 分子名称: | MoeN5,DNA-binding protein 7d, methyl (2R)-3-dimethoxyphosphoryloxy-2-[(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]propanoate | | 著者 | Ko, T.-P, Guo, R.-T, Chen, C.-C. | | 登録日 | 2016-09-14 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism.
Biochem. Biophys. Res. Commun., 511, 2019
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5GWV
 | | Structure of MoeN5-Sso7d fusion protein in complex with a substrate analogue | | 分子名称: | (2R)-3-dimethoxyphosphoryloxy-2-[(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]propanoic acid, MoeN5,DNA-binding protein 7d | | 著者 | Ko, T.-P, Guo, R.-T, Chen, C.-C. | | 登録日 | 2016-09-14 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism.
Biochem. Biophys. Res. Commun., 511, 2019
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2CAU
 | | CANAVALIN FROM JACK BEAN | | 分子名称: | PROTEIN (CANAVALIN) | | 著者 | Ko, T.-P, Day, J, Macpherson, A. | | 登録日 | 1998-11-20 | | 公開日 | 1998-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The refined structure of canavalin from jack bean in two crystal forms at 2.1 and 2.0 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
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2CAV
 | | CANAVALIN FROM JACK BEAN | | 分子名称: | PROTEIN (CANAVALIN) | | 著者 | Ko, T.-P, Day, J, Macpherson, A. | | 登録日 | 1998-11-20 | | 公開日 | 1998-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The refined structure of canavalin from jack bean in two crystal forms at 2.1 and 2.0 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
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3LBM
 | | D-sialic acid aldolase | | 分子名称: | N-acetylneuraminate lyase, SULFATE ION | | 著者 | Ko, T.-P, Chou, C.-Y, Wang, A.H.-J. | | 登録日 | 2010-01-08 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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5B01
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3FWN
 | | Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate | | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, ... | | 著者 | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2009-01-19 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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4EM2
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1M7J
 | | Crystal structure of D-aminoacylase defines a novel subset of amidohydrolases | | 分子名称: | ACETATE ION, D-aminoacylase, ZINC ION | | 著者 | Liaw, S.-H, Chen, S.-J, Ko, T.-P, Hsu, C.-S, Wang, A.H.-J, Tsai, Y.-C. | | 登録日 | 2002-07-22 | | 公開日 | 2003-02-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of D-Aminoacylase from Alcaligenes faecalis DA1. A NOVEL SUBSET OF AMIDOHYDROLASES AND INSIGHTS INTO THE ENZYME MECHANISM.
J.Biol.Chem., 278, 2003
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3KRF
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (I) | | 分子名称: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | 著者 | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | 登録日 | 2009-11-18 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRC
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with IPP | | 分子名称: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | 著者 | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | 登録日 | 2009-11-18 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRP
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium and GPP | | 分子名称: | 1,2-ETHANEDIOL, GERANYL DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | 著者 | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | 登録日 | 2009-11-19 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRA
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium | | 分子名称: | 1,2-ETHANEDIOL, Geranyl diphosphate synthase large subunit, Geranyl diphosphate synthase small subunit, ... | | 著者 | Chang, T.-H, Ko, T.-P, Hsieh, F.-L, Wang, A.H.-J. | | 登録日 | 2009-11-18 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRO
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (II) | | 分子名称: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | 著者 | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | 登録日 | 2009-11-19 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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5FNY
 | | Low solvent content crystal form of Zn containing Iron sulfur cluster repair protein YtfE | | 分子名称: | FE (III) ION, IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE, NONAETHYLENE GLYCOL, ... | | 著者 | Lo, F.-C, Hsieh, C.-C, Maestre-Reyna, M, Chen, C.-Y, Ko, T.-P, Horng, Y.-C, Lai, Y.-C, Chiang, Y.-W, Chou, C.-M, Chiang, C.-H, Huang, W.-N, Liaw, W.-F. | | 登録日 | 2015-11-17 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
Chemistry, 22, 2016
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5FNP
 | | High resolution Zn containing Iron sulfur cluster repair protein YtfE | | 分子名称: | CHLORIDE ION, IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE, OXYGEN ATOM, ... | | 著者 | Lo, F.-C, Hsieh, C.-C, Maestre-Reyna, M, Chen, C.-Y, Ko, T.-P, Horng, Y.-C, Lai, Y.-C, Chiang, Y.-W, Chou, C.-M, Chiang, C.-H, Huang, W.-N, Liaw, W.-F. | | 登録日 | 2015-11-16 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
Chemistry, 22, 2016
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5FNN
 | | Iron and Selenomethionine containing Iron sulfur cluster repair protein YtfE | | 分子名称: | CHLORIDE ION, FE (II) ION, FE (III) ION, ... | | 著者 | Lo, F.-C, Hsieh, C.-C, Maestre-Reyna, M, Chen, C.-Y, Ko, T.-P, Horng, Y.-C, Lai, Y.-C, Chiang, Y.-W, Chou, C.-M, Chiang, C.-H, Huang, W.-N, Liaw, W.-F. | | 登録日 | 2015-11-16 | | 公開日 | 2016-04-27 | | 最終更新日 | 2017-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
Chemistry, 22, 2016
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2DH4
 | | Geranylgeranyl pyrophosphate synthase | | 分子名称: | MAGNESIUM ION, YPL069C | | 著者 | Chang, T.-H, Guo, R.-T, Ko, T.-P, Wang, A.H, Liang, P.-H. | | 登録日 | 2006-03-22 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase from Saccharomyces cerevisiae and the Mechanism of Product Chain Length Determination.
J.Biol.Chem., 281, 2006
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1UEH
 | | E. coli undecaprenyl pyrophosphate synthase in complex with Triton X-100, magnesium and sulfate | | 分子名称: | MAGNESIUM ION, OXTOXYNOL-10, SULFATE ION, ... | | 著者 | Chang, S.-Y, Ko, T.-P, Liang, P.-H, Wang, A.H.-J. | | 登録日 | 2003-05-15 | | 公開日 | 2003-08-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton
J.Biol.Chem., 278, 2003
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