5GWW

Structure of MoeN5-Sso7d fusion protein in complex with a permethylated substrate analogue

Summary for 5GWW

Entry DOI	10.2210/pdb5gww/pdb
Related	5B02 5GWV 6J8V 6J8W
Descriptor	MoeN5,DNA-binding protein 7d, methyl (2R)-3-dimethoxyphosphoryloxy-2-[(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]propanoate (3 entities in total)
Functional Keywords	moenomycin, antibiotics, biosynthesis, prenyl transferase, alpha helical, transferase, dna binding protein
Biological source	Streptomyces ghanaensis More
Total number of polymer chains	4
Total formula weight	150759.61
Authors	Ko, T.-P.,Guo, R.-T.,Chen, C.-C. (deposition date: 2016-09-14, release date: 2017-09-20, Last modification date: 2023-11-08)
Primary citation	Zhang, L.,Ko, T.-P.,Malwal, S.R.,Liu, W.,Zhou, S.,Yu, X.,Oldfield, E.,Guo, R.-T.,Chen, C.-C. Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism. Biochem. Biophys. Res. Commun., 511:800-805, 2019 Cited by PubMed: 30837154 DOI: 10.1016/j.bbrc.2019.02.131 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation