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3L4G
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Crystal structure of Homo Sapiens cytoplasmic Phenylalanyl-tRNA synthetase
分子名称: PHENYLALANINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain
著者Finarov, I, Moor, N, Kessler, N, Klipcan, L, Safro, M.G.
登録日2009-12-20
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of human cytosolic phenylalanyl-tRNA synthetase: evidence for kingdom-specific design of the active sites and tRNA binding patterns.
Structure, 18, 2010
3HFZ
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Crystal structure of Thermus thermophilus Phenylalanyl-tRNA synthetase complexed with m-tyrosine
分子名称: META-TYROSINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain
著者Klipcan, L, Moor, N, Kessler, N, Safro, M.G.
登録日2009-05-13
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
3HFV
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Crystal structure of human mitochondrial phenylalanyl-tRNA synthetase complexed with m-tyrosine
分子名称: META-TYROSINE, Phenylalanyl-tRNA synthetase, mitochondrial
著者Klipcan, L, Moor, N, Kessler, N, Safro, M.G.
登録日2009-05-12
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
3TUP
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BU of 3tup by Molmil
Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state
分子名称: Phenylalanyl-tRNA synthetase, mitochondrial, Thermus thermophilus tRNAPhe
著者Safro, M, Klipcan, L, Moor, N, Finarov, I, Kessler, N, Sukhanova, M.
登録日2011-09-17
公開日2011-11-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active "Open" State.
J.Mol.Biol., 415, 2012
3CMQ
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BU of 3cmq by Molmil
Crystal structure of human mitochondrial phenylalanine tRNA synthetase
分子名称: ADENOSINE-5'-[PHENYLALANINYL-PHOSPHATE], MAGNESIUM ION, Phenylalanyl-tRNA synthetase, ...
著者Klipcan, L, Levin, I.L, Kessler, N, Moor, N, Finarov, I, Safro, M.
登録日2008-03-24
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The tRNA-Induced Conformational Activation of Human Mitochondrial Phenylalanyl-tRNA Synthetase.
Structure, 16, 2008
1NIZ
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BU of 1niz by Molmil
NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: Exterior membrane glycoprotein(GP120)
著者Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J.
登録日2002-12-30
公開日2003-02-25
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
1NJ0
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BU of 1nj0 by Molmil
NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: Exterior membrane glycoprotein(GP120)
著者Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J.
登録日2002-12-30
公開日2003-02-25
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
3PCO
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BU of 3pco by Molmil
crystal structure of E. coli phenylalanine-tRNA synthetase complexed with phenylalanine and AMP
分子名称: ADENOSINE MONOPHOSPHATE, PHENYLALANINE, Phenylalanyl-tRNA synthetase, ...
著者Mermershtain, I, Finarov, I, Klipcan, L, Kessler, N, Rozenberg, H, Safro, M.G.
登録日2010-10-21
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Idiosyncrasy and identity in the prokaryotic phe-system: crystal structure of E. coli phenylalanyl-tRNA synthetase complexed with phenylalanine and AMP.
Protein Sci., 20, 2011
2HYM
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BU of 2hym by Molmil
NMR based Docking Model of the Complex between the Human Type I Interferon Receptor and Human Interferon alpha-2
分子名称: Interferon alpha-2, Soluble IFN alpha/beta receptor
著者Quadt-Akabayov, S.R, Chill, J.H, Levy, R, Kessler, N, Anglister, J.
登録日2006-08-07
公開日2006-10-10
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex
Protein Sci., 15, 2006
2L87
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BU of 2l87 by Molmil
The 27-residue N-terminus CCR5-peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide
分子名称: C-C chemokine receptor type 5
著者Schnur, E, Noah, E, Ayzenshtat, I, Sargsyan, H, Inui, T, Ding, F.X, Arshava, B, Sagi, Y, Kessler, N, Levy, R, Scherf, T, Naider, F, Anglister, J.
登録日2011-01-06
公開日2011-07-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic Peptide.
J.Mol.Biol., 410, 2011
1U6U
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BU of 1u6u by Molmil
NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: V3 peptide
著者Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
登録日2004-08-02
公開日2005-04-05
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1U6V
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BU of 1u6v by Molmil
NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: V3 peptide
著者Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
登録日2004-08-02
公開日2005-04-05
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
2ADY
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BU of 2ady by Molmil
Structural Basis of DNA Recognition by p53 Tetramers (complex IV)
分子名称: 5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
著者Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
登録日2005-07-21
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2AC0
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BU of 2ac0 by Molmil
Structural Basis of DNA Recognition by p53 Tetramers (complex I)
分子名称: 5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
著者Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
登録日2005-07-18
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2ATA
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BU of 2ata by Molmil
Structural Basis of DNA Recognition by p53 Tetramers (complex II)
分子名称: 5'-D(*AP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*T)-3', Cellular tumor antigen p53, ZINC ION
著者Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
登録日2005-08-24
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2AHI
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Structural Basis of DNA Recognition by p53 Tetramers (complex III)
分子名称: 5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
著者Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
登録日2005-07-28
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
1MD9
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BU of 1md9 by Molmil
CRYSTAL STRUCTURE OF DhbE IN COMPLEX WITH DHB AND AMP
分子名称: 2,3-DIHYDROXY-BENZOIC ACID, 2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE
著者May, J.J, Kessler, N, Marahiel, M.A, Stubbs, M.T.
登録日2002-08-07
公開日2002-09-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1MDF
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BU of 1mdf by Molmil
CRYSTAL STRUCTURE OF DhbE IN ABSENCE OF SUBSTRATE
分子名称: 2,3-dihydroxybenzoate-AMP ligase, SULFATE ION
著者May, J.J, Kessler, N, Marahiel, M.A, Stubbs, M.T.
登録日2002-08-07
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1MDB
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CRYSTAL STRUCTURE OF DhbE IN COMPLEX WITH DHB-ADENYLATE
分子名称: 2,3-DIHYDROXY-BENZOIC ACID, 2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE, ...
著者May, J.J, Kessler, N, Marahiel, M.A, Stubbs, M.T.
登録日2002-08-07
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
2MZX
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BU of 2mzx by Molmil
CCR5-ECL2 helical structure, residues Q186-T195
分子名称: C-C chemokine receptor type 5
著者Abayev, M, Anglister, J.
登録日2015-02-26
公開日2015-04-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions.
Febs J., 282, 2015
3D08
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BU of 3d08 by Molmil
Human p53 core domain with hot spot mutation R249S and second-site suppressor mutation H168R
分子名称: Cellular tumor antigen p53, ZINC ION
著者Suad, O, Rozenberg, H, Shimon, L.J.W, Frolow, F, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D06
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BU of 3d06 by Molmil
Human p53 core domain with hot spot mutation R249S (I)
分子名称: Cellular tumor antigen p53, ZINC ION
著者Rozenberg, H, Suad, O, Shimon, L.J.W, Frolow, F, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D07
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Human p53 core domain with hot spot mutation R249S (III)
分子名称: Cellular tumor antigen p53, ZINC ION
著者Suad, O, Rozenberg, H, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D09
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Human p53 core domain with hot spot mutation R249S and second-site suppressor mutations H168R and T123A
分子名称: Cellular tumor antigen p53, ZINC ION
著者Rozenberg, H, Suad, O, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D0A
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Human p53 core domain with hot spot mutation R249S and second site suppressor mutation H168R in sequence-specific complex with DNA
分子名称: Cellular tumor antigen p53, DNA (5'-D(*DCP*DGP*DGP*DGP*DCP*DAP*DTP*DGP*DCP*DCP*DCP*DG)-3'), ZINC ION
著者Suad, O, Rozenberg, H, Shakked, Z.
登録日2008-05-01
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009

 

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