6CUL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cul by Molmil](/molmil-images/mine/6cul) | PvdF of pyoverdin biosynthesis is a structurally unique N10-formyltetrahydrofolate-dependent formyltransferase | Descriptor: | CITRIC ACID, N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzene-1-carbonyl)-D-glutamic acid, Pyoverdine synthetase F | Authors: | Kenjic, N, Hoag, M.R, Moraski, G.C, Caperelli, C.A, Moran, G.R, Lamb, A.L. | Deposit date: | 2018-03-26 | Release date: | 2019-02-06 | Last modified: | 2019-11-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | PvdF of pyoverdin biosynthesis is a structurally unique N10-formyltetrahydrofolate-dependent formyltransferase. Arch. Biochem. Biophys., 664, 2019
|
|
7UF3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uf3 by Molmil](/molmil-images/mine/7uf3) | RibB from Vibrio cholera bound with L-xylulose-5-phosphate (L-Xy5P) and manganese | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, L-xylulose-5-phosphate, MANGANESE (II) ION | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
7UF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uf5 by Molmil](/molmil-images/mine/7uf5) | RibB from Vibrio cholera bound with intermediate 2 in the reaction cycle and the products DHBP and formate | Descriptor: | (2R)-2-(dihydroxymethyl)-2-hydroxy-3-oxobutyl dihydrogen phosphate, (2R)-2-hydroxy-3-oxobutyl dihydrogen phosphate, 3,4-dihydroxy-2-butanone 4-phosphate synthase, ... | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
7UEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uez by Molmil](/molmil-images/mine/7uez) | Apo RibB from Vibrio cholera | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
7UF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uf0 by Molmil](/molmil-images/mine/7uf0) | RibB from Vibrio cholera bound with D-ribulose-5-phosphate (D-Ru5P) | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, RIBULOSE-5-PHOSPHATE | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
7UF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uf1 by Molmil](/molmil-images/mine/7uf1) | RibB from Vibrio cholera bound with D-Ribose-5-phosphate (D-R5P) and manganese | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, MANGANESE (II) ION, RIBOSE-5-PHOSPHATE | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
7UF2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uf2 by Molmil](/molmil-images/mine/7uf2) | RibB from Vibrio cholera bound with D-xylulose-5-phosphate (D-Xy5P) and manganese | Descriptor: | 1,2-ETHANEDIOL, 3,4-dihydroxy-2-butanone 4-phosphate synthase, 5-O-phosphono-D-xylulose, ... | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
7UF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uf4 by Molmil](/molmil-images/mine/7uf4) | RibB from Vibrio cholera bound with intermediate 1 of the reaction cycle and D-ribulose-5-phosphate (D-Ru5P) | Descriptor: | (2R)-2-hydroxy-3,4-dioxopentyl dihydrogen phosphate, 1,2-ETHANEDIOL, 3,4-dihydroxy-2-butanone 4-phosphate synthase, ... | Authors: | Kenjic, N, Meneely, K.M, Lamb, A.L. | Deposit date: | 2022-03-22 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144, 2022
|
|
8GL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gl9 by Molmil](/molmil-images/mine/8gl9) | Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE | Descriptor: | CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen | Authors: | Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J. | Deposit date: | 2023-03-21 | Release date: | 2023-07-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Small molecule targeting of transcription-replication conflict for selective chemotherapy. Cell Chem Biol, 30, 2023
|
|
6VBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vbx by Molmil](/molmil-images/mine/6vbx) | Crystal structure of Mcl-1 in complex with 138E12 peptide, Lys-covalent antagonist | Descriptor: | Induced myeloid leukemia cell differentiation protein Mcl-1, Synthetic peptide | Authors: | Pellecchia, M, Perry, J.J, Kenjic, N, Assar, Z. | Deposit date: | 2019-12-19 | Release date: | 2020-12-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Design, Synthesis, and Structural Characterization of Lysine Covalent BH3 Peptides Targeting Mcl-1. J.Med.Chem., 64, 2021
|
|
6UMQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6umq by Molmil](/molmil-images/mine/6umq) | Structure of DUF89 | Descriptor: | Damage-control phosphatase DUF89, MAGNESIUM ION | Authors: | Perry, J.J, Kenjic, N, Dennis, T.N. | Deposit date: | 2019-10-10 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Human ARMT1 structure and substrate specificity indicates that it is a DUF89 family damage-control phosphatase. J.Struct.Biol., 212, 2020
|
|
6UMR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6umr by Molmil](/molmil-images/mine/6umr) | Structure of DUF89 - D291A mutant | Descriptor: | Damage-control phosphatase DUF89, MAGNESIUM ION | Authors: | Perry, J.J, Kenjic, N, Dennis, T.N. | Deposit date: | 2019-10-10 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Human ARMT1 structure and substrate specificity indicates that it is a DUF89 family damage-control phosphatase. J.Struct.Biol., 212, 2020
|
|
8GLA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gla by Molmil](/molmil-images/mine/8gla) | |