7UF5

RibB from Vibrio cholera bound with intermediate 2 in the reaction cycle and the products DHBP and formate

Summary for 7UF5

Entry DOI	10.2210/pdb7uf5/pdb
Descriptor	3,4-dihydroxy-2-butanone 4-phosphate synthase, (2R)-2-(dihydroxymethyl)-2-hydroxy-3-oxobutyl dihydrogen phosphate, (2R)-2-hydroxy-3-oxobutyl dihydrogen phosphate, ... (6 entities in total)
Functional Keywords	ribb, riboflavin, 3, 4-dihydroxy-2-butanone 4-phosphate synthase, lyase
Biological source	Vibrio cholerae
Total number of polymer chains	1
Total formula weight	24105.11
Authors	Kenjic, N.,Meneely, K.M.,Lamb, A.L. (deposition date: 2022-03-22, release date: 2022-07-20, Last modification date: 2023-10-18)
Primary citation	Kenjic, N.,Meneely, K.M.,Wherritt, D.J.,Denler, M.C.,Jackson, T.A.,Moran, G.R.,Lamb, A.L. Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. J.Am.Chem.Soc., 144:12769-12780, 2022 Cited by PubMed: 35802469 DOI: 10.1021/jacs.2c03376 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation