8D9H
 
 | | gRAMP-TPR-CHAT match PFS target RNA(Craspase) | | 分子名称: | CHAT domain protein, PHOSPHATE ION, RAMP superfamily protein, ... | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-09 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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8D9F
 | | gRAMP-TPR-CHAT (Craspase) | | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-09 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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8D97
 | | Apo gRAMP | | 分子名称: | RAMP superfamily protein, RNA (42-MER), ZINC ION | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-09 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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8D9I
 | | gRAMP non-matching PFS-with Mg | | 分子名称: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*A)-3'), ... | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-09 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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8D9E
 | | gRAMP-match PFS target | | 分子名称: | RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*UP*A)-3'), ... | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-09 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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8D9G
 | | gRAMP-TPR-CHAT Non match PFS target RNA(Craspase) | | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (36-MER), ... | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-09 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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8D8N
 | | gRAMP non-match PFS target RNA | | 分子名称: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*AP*CP*A)-3'), ... | | 著者 | Hu, C, Nam, K.H, Schuler, G, Ke, A. | | 登録日 | 2022-06-08 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
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4Y1M
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4Y1I
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4Y1J
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2XXA
 | | The Crystal Structure of the Signal Recognition Particle (SRP) in Complex with its Receptor(SR) | | 分子名称: | 4.5S RNA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Ataide, S.F, Schmitz, N, Shen, K, Ke, A, Shan, S, Doudna, J.A, Ban, N. | | 登録日 | 2010-11-09 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | | 主引用文献 | The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Science, 331, 2011
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8G9S
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | 分子名称: | AcrIC8, Cas11, Cas5, ... | | 著者 | Hu, C, Nam, K.H, Ke, A. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8G9T
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | 分子名称: | AcrIC9, Cas11, Cas5, ... | | 著者 | Hu, C, Nam, K.H, Ke, A. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8G9U
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | 分子名称: | CRISPR-associated protein, Csd1 family, Csd2 family, ... | | 著者 | Hu, C, Nam, K.H, Ke, A. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8GAF
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | 分子名称: | Cas11, Cas5, Cas7, ... | | 著者 | Hu, C, Nam, K.H, Ke, A. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8GAM
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | 分子名称: | Cas11, Cas5, Cas7, ... | | 著者 | Hu, C, Nam, K.H, Ke, A. | | 登録日 | 2023-02-23 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8GAN
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | 分子名称: | Cas11, Cas5, Cas7, ... | | 著者 | Hu, C, Nam, K.H, Ke, A. | | 登録日 | 2023-02-23 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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3R4F
 | | Prohead RNA | | 分子名称: | MAGNESIUM ION, pRNA | | 著者 | Ding, F, Lu, C, Zhano, W, Rajashankar, K.R, Anderson, D.L, Jardine, P.J, Grimes, S, Ke, A. | | 登録日 | 2011-03-17 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure and assembly of the essential RNA ring component of a viral DNA packaging motor.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7R2K
 | | elongated Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Terns, M, Stahlberg, H, Ke, A. | | 登録日 | 2022-02-04 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural snapshots for an atypic type I CRISPR-Cas system
To Be Published
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7TRA
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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7TR9
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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7TR8
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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7TR6
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | Cas11a, Cas5a, Cas7a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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7UTN
 | | IscB and wRNA bound to Target DNA | | 分子名称: | DNA non-target strand, DNA target strand, IscB, ... | | 著者 | Schuler, G.A, Hu, C, Ke, A. | | 登録日 | 2022-04-27 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9.
Science, 376, 2022
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8CSZ
 | | IscB and wRNA bound to Target DNA | | 分子名称: | DNA non-target strand, DNA target strand, IscB, ... | | 著者 | Schuler, G.A, Hu, C, Ke, A. | | 登録日 | 2022-05-13 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9.
Science, 376, 2022
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