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1KOU
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BU of 1kou by Molmil
Crystal Structure of the Photoactive Yellow Protein Reconstituted with Caffeic Acid at 1.16 A Resolution
Descriptor: CAFFEIC ACID, N-BUTANE, PHOTOACTIVE YELLOW PROTEIN
Authors:van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2001-12-22
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1KSY
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BU of 1ksy by Molmil
Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex
Descriptor: E1 Recognition Sequence, Strand 1, Strand 2, ...
Authors:Enemark, E.J, Stenlund, A, Joshua-Tor, L.
Deposit date:2002-01-14
Release date:2002-03-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
1KSX
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BU of 1ksx by Molmil
Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex
Descriptor: E1 Recognition Sequence, REPLICATION PROTEIN E1
Authors:Enemark, E.J, Stenlund, A, Joshua-Tor, L.
Deposit date:2002-01-14
Release date:2002-03-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
1CP2
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BU of 1cp2 by Molmil
NITROGENASE IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM
Descriptor: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
Authors:Schlessman, J.L, Woo, D, Joshua-Tor, L, Howard, J.B, Rees, D.C.
Deposit date:1998-05-11
Release date:1998-11-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum.
J.Mol.Biol., 280, 1998
1CY5
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BU of 1cy5 by Molmil
CRYSTAL STRUCTURE OF THE APAF-1 CARD
Descriptor: BETA-MERCAPTOETHANOL, PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1), ZINC ION
Authors:Vaughn, D.E, Joshua-Tor, L.
Deposit date:1999-08-31
Release date:1999-09-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.
J.Mol.Biol., 293, 1999
1CW9
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BU of 1cw9 by Molmil
DNA DECAMER WITH AN ENGINEERED CROSSLINK IN THE MINOR GROOVE
Descriptor: 5'-D(*CP*CP*AP*GP*(G47)P*CP*CP*TP*GP*G)-3', CALCIUM ION
Authors:van Aalten, D.M.F, Erlanson, D.A, Verdine, G.L, Joshua-Tor, L.
Deposit date:1999-08-26
Release date:1999-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A structural snapshot of base-pair opening in DNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
1D7E
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BU of 1d7e by Molmil
CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:1999-10-17
Release date:2000-03-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Conformational substates in different crystal forms of the photoactive yellow protein--correlation with theoretical and experimental flexibility.
Protein Sci., 9, 2000
1F08
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BU of 1f08 by Molmil
CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN E1 FROM PAPILLOMAVIRUS
Descriptor: BROMIDE ION, REPLICATION PROTEIN E1
Authors:Enemark, E.J, Chen, G, Vaughn, D.E, Stenlund, A, Joshua-Tor, L.
Deposit date:2000-05-15
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus.
Mol.Cell, 6, 2000
1F57
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BU of 1f57 by Molmil
CARBOXYPEPTIDASE A COMPLEX WITH D-CYSTEINE AT 1.75 A
Descriptor: CARBOXYPEPTIDASE A, D-CYSTEINE, ZINC ION
Authors:van Aalten, D.M, Chong, C.R, Joshua-Tor, L.
Deposit date:2000-06-13
Release date:2000-09-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.
Biochemistry, 39, 2000
7JPP
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BU of 7jpp by Molmil
ORC-O2WH: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC1 AAA+ domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPR
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BU of 7jpr by Molmil
ORC-OPEN: Human Origin Recognition Complex (ORC) in an open conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPS
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BU of 7jps by Molmil
ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-09
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPQ
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BU of 7jpq by Molmil
ORC-O2-5: Human Origin Recognition Complex (ORC) with subunits 2,3,4,5
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 2, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPO
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BU of 7jpo by Molmil
ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
5T7B
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BU of 5t7b by Molmil
Argonaute-2 - 5'-(E)-vinylphosphonate 2'-O-methyl-uridine modified mrTTR guide RNA complex
Descriptor: PHENOL, Protein argonaute-2, RNA (UVP)UAUAGAGCAAGAACACUGUU
Authors:Elkayam, E, Joshua-Tor, L.
Deposit date:2016-09-02
Release date:2016-12-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.529 Å)
Cite:Protein structure
To Be Published
5UJM
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BU of 5ujm by Molmil
Structure of the active form of human Origin Recognition Complex and its ATPase motor module
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Tocilj, A, On, K, Yuan, Z, Sun, J, Elkayam, E, Li, H, Stillman, B, Joshua-Tor, L.
Deposit date:2017-01-18
Release date:2017-02-08
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
5UJ8
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BU of 5uj8 by Molmil
Human Origin Recognition Complex subunits 2 and 3
Descriptor: Origin recognition complex subunit 2, Origin recognition complex subunit 3
Authors:Tocilj, A, On, K.F, Elkayam, E, Joshua-Tor, L.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
5UJ7
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BU of 5uj7 by Molmil
Structure of the active form of human Origin Recognition Complex ATPase motor module, complex subunitS 1, 4, 5
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Tocilj, A, Elkayam, E, On, K.F, Joshua-Tor, L.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.394 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
5VF6
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BU of 5vf6 by Molmil
Crystal structure of single chain variable fragment (scFv45).
Descriptor: single chain variable fragment
Authors:Shrestha, O.K, Tocilj, A, Joshua-Tor, L, Tonks, N.K.
Deposit date:2017-04-06
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.635 Å)
Cite:Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.
Nat Commun, 9, 2018
5W0M
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BU of 5w0m by Molmil
Structure of human TUT7 catalytic module (CM) in complex with U5 RNA
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0B
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BU of 5w0b by Molmil
Structure of human TUT7 catalytic module (CM)
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-30
Release date:2017-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.614 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0O
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BU of 5w0o by Molmil
Structure of human TUT7 catalytic module (CM) in complex with dsRNA
Descriptor: Terminal uridylyltransferase 7, URIDINE 5'-TRIPHOSPHATE, double-stranded RNA
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0N
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BU of 5w0n by Molmil
Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W6V
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BU of 5w6v by Molmil
The Structure of human Argonaute-1 in complex with the hook motif of human GW182
Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein
Authors:Elkayam, E, Faehnle, C.R, Joshua-Tor, L.
Deposit date:2017-06-17
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.828 Å)
Cite:Multivalent Recruitment of Human Argonaute by GW182.
Mol. Cell, 67, 2017
1Z25
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BU of 1z25 by Molmil
Structure of P.furiosus Argonaute with bound Mn2+
Descriptor: Argonaute, MANGANESE (II) ION
Authors:Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005

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