7JPP

ORC-O2WH: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC1 AAA+ domain

Summary for 7JPP

• Entry DOI: 10.2210/pdb7jpp/pdb
• EMDB information: 22418
• Descriptor: Origin recognition complex subunit 1, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ... (7 entities in total)
• Functional Keywords: replication, aaa+, orc, dna-binding, cryoem
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 294666.57

Authors

Jaremko, M.J.,Joshua-Tor, L. (deposition date: 2020-08-09, release date: 2020-09-09, Last modification date: 2024-03-06)

• Primary citation: Jaremko, M.J.,On, K.F.,Thomas, D.R.,Stillman, B.,Joshua-Tor, L.; The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.; Elife, 9:-, 2020; PubMed: 32808929; DOI: 10.7554/eLife.58622

Experimental method

ELECTRON MICROSCOPY (3.7 Å)