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2JG6
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BU of 2jg6 by Molmil
CRYSTAL STRUCTURE OF A 3-METHYLADENINE DNA GLYCOSYLASE I FROM STAPHYLOCOCCUS AUREUS
Descriptor: DNA-3-METHYLADENINE GLYCOSIDASE, ZINC ION
Authors:Yan, X, Carter, L.G, Liu, H, Dorward, M, McMahon, S.A, Johnson, K.A, Oke, M, Coote, P.J, Naismith, J.H.
Deposit date:2007-02-08
Release date:2007-02-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2JGT
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BU of 2jgt by Molmil
Low resolution structure of SPT
Descriptor: SERINE PALMITOYLTRANSFERASE
Authors:Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J.
Deposit date:2007-02-14
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis.
J.Mol.Biol., 370, 2007
1VYF
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BU of 1vyf by Molmil
schistosoma mansoni fatty acid binding protein in complex with oleic acid
Descriptor: 14 KDA FATTY ACID BINDING PROTEIN, OLEIC ACID
Authors:Angelucci, F, Johnson, K.A, Baiocco, P, Miele, A.E, Bellelli, A.
Deposit date:2004-04-29
Release date:2004-09-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure
Biochemistry, 43, 2004
1VK5
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BU of 1vk5 by Molmil
X-ray Structure of Gene Product from Arabidopsis Thaliana At3g22680
Descriptor: 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, SULFATE ION, ...
Authors:Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2004-05-06
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana.
Acta Crystallogr.,Sect.F, 61, 2005
1VJI
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BU of 1vji by Molmil
Gene Product of At1g76680 from Arabidopsis thaliana
Descriptor: 12-oxophytodienoate reductase (OPR1), FLAVIN MONONUCLEOTIDE
Authors:Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2004-02-24
Release date:2004-03-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:X-ray structure of Arabidopsis At1g77680, 12-oxophytodienoate reductase isoform 1.
Proteins, 61, 2005
1VYG
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BU of 1vyg by Molmil
schistosoma mansoni fatty acid binding protein in complex with arachidonic acid
Descriptor: ARACHIDONIC ACID, FATTY ACID BINDING PROTEIN
Authors:Angelucci, F, Johnson, K.A, Baiocco, P, Miele, A.E, Bellelli, A.
Deposit date:2004-04-29
Release date:2004-09-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure
Biochemistry, 43, 2004
2BON
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BU of 2bon by Molmil
Structure of an Escherichia coli lipid kinase (YegS)
Descriptor: LIPID KINASE, MAGNESIUM ION
Authors:Bakali, H.M, Johnson, K.A, Hallberg, B.M, Herman, M.D, Nordlund, P.
Deposit date:2005-04-12
Release date:2006-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Yegs, a Homologue to the Mammalian Diacylglycerol Kinases, Reveals a Novel Regulatory Metal Binding Site.
J.Biol.Chem., 282, 2007
3OHT
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BU of 3oht by Molmil
Crystal Structure of Salmo Salar p38alpha
Descriptor: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, SULFATE ION, p38a
Authors:Rothweiler, U, Johnson, K, Engh, R.A.
Deposit date:2010-08-18
Release date:2011-06-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:p38alpha MAP kinase dimers with swapped activation segments and a novel catalytic loop conformation
J.Mol.Biol., 411, 2011
6XNN
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BU of 6xnn by Molmil
Crystal Structure of Mouse STING CTD complex with SR-717.
Descriptor: 4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid, Stimulator of interferon genes protein
Authors:Chin, E.N, Yu, C, Wolan, D.W, Petrassi, H.M, Lairson, L.L.
Deposit date:2020-07-03
Release date:2020-08-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic.
Science, 369, 2020
7RTP
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BU of 7rtp by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea]
Descriptor: JTO light chain, N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-08-13
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.
Bioorg.Med.Chem.Lett., 60, 2022
6XNP
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BU of 6xnp by Molmil
Crystal Structure of Human STING CTD complex with SR-717
Descriptor: 1,2-ETHANEDIOL, 4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid, GLYCEROL, ...
Authors:Chin, E.N, Yu, C, Wolan, D.W, Petrassi, H.M, Lairson, L.L.
Deposit date:2020-07-03
Release date:2020-08-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic.
Science, 369, 2020
7S3V
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BU of 7s3v by Molmil
Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity towards kynurenine
Descriptor: Kynureninase
Authors:Burkholder, N.T, Zhang, Y.J.
Deposit date:2021-09-08
Release date:2022-12-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.249 Å)
Cite:Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.
Nat Catal, 5, 2022
1GJY
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BU of 1gjy by Molmil
The X-ray structure of the Sorcin Calcium Binding Domain (SCBD) provides insight into the phosphorylation and calcium dependent processess
Descriptor: SORCIN, SULFATE ION
Authors:Ilari, A, Johnson, K.A, Nastopoulos, V, Tsernoglou, D, Chiancone, E.
Deposit date:2001-08-06
Release date:2002-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Sorcin Calcium Binding Domain Provides a Model of Ca(2+)-Dependent Processes in the Full-Length Protein
J.Mol.Biol., 317, 2002
7L1F
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BU of 7l1f by Molmil
SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate
Descriptor: Non-structural protein 7, Non-structural protein 8, RNA (5'-R(P*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*UP*CP*UP*UP*AP*G)-3'), ...
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2020-12-14
Release date:2021-02-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication.
Mol.Cell, 81, 2021
7LMQ
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BU of 7lmq by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 62 [4-methyl-3-(morpholinomethyl)-7-(1-phenylethoxy)-2H-chromen-2-one]
Descriptor: 4-methyl-3-(morpholin-4-ylmethyl)-7-[(1~{R})-1-phenylethoxy]chromen-2-one, JTO light chain, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-02-05
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.
J.Med.Chem., 64, 2021
7LMO
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BU of 7lmo by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 34 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-7-(1H-imidazole-5-carbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione]
Descriptor: (5~{R})-3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-7-(1~{H}-imidazol-4-ylcarbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione, JTO light chain, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-02-05
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.
J.Med.Chem., 64, 2021
7LMN
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BU of 7lmn by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 26 [2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl (3-(1H-imidazol-4-yl)benzyl)carbamate]
Descriptor: 2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl ~{N}-[[3-(1~{H}-imidazol-5-yl)phenyl]methyl]carbamate, JTO light chain, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-02-05
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.
J.Med.Chem., 64, 2021
7LMR
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BU of 7lmr by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 63 [4-methyl-3-(morpholinomethyl)-7-(2-phenylpropoxy)-2H-chromen-2-one]
Descriptor: 4-methyl-3-(morpholin-4-ylmethyl)-7-[(2~{S})-2-phenylpropoxy]chromen-2-one, JTO light chain, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-02-05
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.
J.Med.Chem., 64, 2021
7LMP
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BU of 7lmp by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 36 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-8-(1H-imidazole-4-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione]
Descriptor: 3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-8-(1~{H}-imidazol-5-ylcarbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione, JTO light chain, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-02-05
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.
J.Med.Chem., 64, 2021
1Q53
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BU of 1q53 by Molmil
SOLUTION STRUCTURE OF HYPOTHETICAL ARABIDOPSIS THALIANA PROTEIN AT3G17210. CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS TARGET 13081
Descriptor: expressed protein: At3g17210
Authors:Lytle, B.L, Peterson, F.C, Volkman, B.F, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2003-08-06
Release date:2003-08-19
Last modified:2013-01-30
Method:SOLUTION NMR
Cite:Structure of the hypothetical protein At3g17210 from Arabidopsis thaliana.
J.Biomol.Nmr, 28, 2004
8G2O
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BU of 8g2o by Molmil
Fab structure - Anti-ApoE-7C11 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, anti-ApoE-7C11 heavy chain, anti-ApoE-7C11 light chain
Authors:Marino, C, Arboleda-Velasquez, J.F.
Deposit date:2023-02-06
Release date:2023-10-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
Alzheimers Dement, 20, 2024
2I9Y
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BU of 2i9y by Molmil
Solution structure of Arabidopsis thaliana protein At1g70830, a member of the major latex protein family
Descriptor: major latex protein-like protein 28 or MLP-like protein 28
Authors:Volkman, B.F, de la Cruz, N.B, Lytle, B.L, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-09-06
Release date:2006-09-19
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structures of two Arabidopsis thaliana major latex proteins represent novel helix-grip folds.
Proteins, 76, 2009
2IVY
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BU of 2ivy by Molmil
Crystal structure of hypothetical protein sso1404 from Sulfolobus solfataricus P2
Descriptor: HYPOTHETICAL PROTEIN SSO1404
Authors:Yan, X, Carter, L.G, Dorward, M, Liu, H, McMahon, S.A, Oke, M, Powers, H, White, M.F, Naismith, J.H.
Deposit date:2006-06-22
Release date:2006-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
1TES
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BU of 1tes by Molmil
OXYGEN BINDING MUSCLE PROTEIN
Descriptor: METHYLETHYLAMINE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Smith, R.D, Phillips Jr, G.N, Olson, J.S.
Deposit date:1996-05-06
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of NO-induced oxidation of myoglobin and hemoglobin.
Biochemistry, 35, 1996
6ENK
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BU of 6enk by Molmil
The X-ray crystal structure of DesE bound to desferrioxamine B
Descriptor: DesE, SODIUM ION, desferrioxamine B
Authors:Naismith, J.H, McMahon, S.A, Challis, G.L, Kadi, N, Oke, M, Liu, H, Carter, L.G, Johnson, K.A.
Deposit date:2017-10-05
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018

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