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6U4Y
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BU of 6u4y by Molmil
Crystal Structure of an EZH2-EED Complex in an Oligomeric State
分子名称: Histone-lysine N-methyltransferase EZH2, Polycomb protein EED
著者Jiao, L, Liu, X.
登録日2019-08-26
公開日2020-07-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献A partially disordered region connects gene repression and activation functions of EZH2.
Proc.Natl.Acad.Sci.USA, 117, 2020
5KJH
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BU of 5kjh by Molmil
Crystal structure of an active polycomb repressive complex 2 in the stimulated state
分子名称: Peptide H3K27me3, Putative uncharacterized protein,Zinc finger domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Jiao, L, Liu, X.
登録日2016-06-20
公開日2017-04-19
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Science, 354, 2016
5KKL
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BU of 5kkl by Molmil
Structure of ctPRC2 in complex with H3K27me3 and H3K27M
分子名称: ALA-ALA-ARG-M3L-SER-ALA-PRO-ALA, Putative uncharacterized protein,Histone H3.1 peptide,Zinc finger domain-containing protein, S-ADENOSYLMETHIONINE, ...
著者Jiao, L, Liu, X.
登録日2016-06-21
公開日2017-04-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Science, 354, 2016
5KJI
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BU of 5kji by Molmil
Crystal structure of an active polycomb repressive complex 2 in the basal state
分子名称: Putative uncharacterized protein,Zinc finger domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Jiao, L, Liu, X.
登録日2016-06-20
公開日2017-04-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Science, 354, 2016
4J4V
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BU of 4j4v by Molmil
Pentameric SFTSVN with suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4S
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BU of 4j4s by Molmil
Triple mutant SFTAVN
分子名称: Nucleocapsid protein, SODIUM ION
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.442 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4R
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BU of 4j4r by Molmil
Hexameric SFTSVN
分子名称: Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4X
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BU of 4j4x by Molmil
Crystal structure of GraVN
分子名称: NP protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4W
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BU of 4j4w by Molmil
Crystal structure of BueVN
分子名称: Nucleocapsid
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.661 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4Y
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BU of 4j4y by Molmil
Triple mutant GraVN
分子名称: NP protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-06-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4U
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BU of 4j4u by Molmil
Pentamer SFTSVN
分子名称: Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
2MKZ
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BU of 2mkz by Molmil
solution structure of a protein C-terminal domain
分子名称: Proteasomal ubiquitin receptor ADRM1
著者Feng, Y, Jiao, L.
登録日2014-02-17
公開日2014-12-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mechanism of the Rpn13-induced activation of Uch37
Protein Cell, 5, 2014
4QA8
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BU of 4qa8 by Molmil
Crystal structure of LprF from Mycobacterium bovis
分子名称: (2R)-2-(dodecanoyloxy)propyl (4E,6E,8E,10E,12E)-pentadeca-4,6,8,10,12-pentaenoate, Putative lipoprotein LprF
著者Ha, N.C, Jiao, L, Kim, J.S.
登録日2014-05-02
公開日2014-10-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Crystal structure and functional implications of LprF from Mycobacterium tuberculosis and M. bovis
Acta Crystallogr.,Sect.D, 70, 2014
6NQ3
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BU of 6nq3 by Molmil
Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex
分子名称: Histone-binding protein RBBP4, PHD finger protein 19, Polycomb protein SUZ12, ...
著者Chen, S, Jiao, L, Liu, X.
登録日2019-01-19
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.
Mol.Cell, 77, 2020
4Z85
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BU of 4z85 by Molmil
Crystal structur of Pseudomonas fluorescens 2-nitrobenzoate 2-nitroreductase NbaA
分子名称: 2-nitrobenzoate nitroreductase
著者Ha, N.C, Jiao, L, Kim, J.S.
登録日2015-04-08
公開日2016-01-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Mechanistic Insights into the Pseudomonas fluorescens 2-Nitrobenzoate 2-Nitroreductase NbaA
Appl.Environ.Microbiol., 81, 2015
7TD5
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BU of 7td5 by Molmil
Structure of human PRC2-EZH1 containing phosphorylated SUZ12
分子名称: Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ...
著者Gong, L, Jiao, L, Liu, X.
登録日2021-12-30
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site.
Nat Commun, 13, 2022
4NOJ
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BU of 4noj by Molmil
Crystal structure of the mature form of asparaginyl endopeptidase (AEP)/Legumain activated at pH 3.5
分子名称: Legumain
著者Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOL
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BU of 4nol by Molmil
Crystal structure of proenzyme asparaginyl endopeptidase (AEP)/Legumain mutant D233A at pH 7.5
分子名称: Legumain
著者Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOM
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BU of 4nom by Molmil
Crystal structure of asparaginyl endopeptidase (AEP)/Legumain activated at pH 4.5
分子名称: Legumain
著者Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOK
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BU of 4nok by Molmil
Crystal structure of proenzyme asparaginyl endopeptidase (AEP)/Legumain at pH 7.5
分子名称: Legumain
著者Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
5WAK
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BU of 5wak by Molmil
Crystal Structure of a Suz12-Rbbp4 Binary Complex
分子名称: Histone-binding protein RBBP4, Polycomb protein SUZ12, ZINC ION
著者Chen, S, Jiao, L, Liu, X.
登録日2017-06-26
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
Mol. Cell, 69, 2018
5WAI
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BU of 5wai by Molmil
Crystal Structure of a Suz12-Rbbp4-Jarid2-Aebp2 Heterotetrameric Complex
分子名称: Histone-binding protein RBBP4, Jumonji, AT-rich interactive domain 2, ...
著者Chen, S, Jiao, L, Liu, X.
登録日2017-06-26
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
Mol. Cell, 69, 2018
4PWO
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BU of 4pwo by Molmil
Crystal structure of DsbA from the Gram positive bacterium Corynebacterium diphtheriae
分子名称: DsbA, GLYCEROL
著者Um, S.H, Kim, J.S, Jiao, L, Yoon, B.Y, Jo, I, Ha, N.C.
登録日2014-03-21
公開日2015-03-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystal structure and biochemical characterization of DsbA from the Gram positive bacterium Corynebacterium diphtheriae
To be Published
4PWP
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BU of 4pwp by Molmil
Crystal structure of DsbA from the Gram positive bacterium Corynebacterium diphtheriae
分子名称: DsbA, GLYCEROL
著者Um, S.H, Kim, J.S, Jiao, L, Yoon, B.Y, Jo, I, Ha, N.C.
登録日2014-03-21
公開日2015-03-25
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Crystal structure and biochemical characterization of DsbA from the Gram positive bacterium Corynebacterium diphtheriae
To be Published
7C91
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BU of 7c91 by Molmil
Blasnase-T13A with D-asn
分子名称: D-ASPARAGINE, FORMIC ACID, L-asparaginase, ...
著者Lu, F, Ran, T, Jiao, L, Wang, W.
登録日2020-06-04
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021

 

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