4CTH
 
 | | Neprilysin variant G399V,G714K in complex with phosphoramidon | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... | | 著者 | Webster, C.I, Burrell, M, Olsson, L, Fowler, S.B, Digby, S, Sandercock, A, Snijder, A, Tebbe, J, Haupts, U, Grudzinska, J, Jermutus, L, Andersson, C. | | 登録日 | 2014-03-13 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Engineering Neprilysin Activity and Specificity to Create a Novel Therapeutic for Alzheimer'S Disease.
Plos One, 9, 2014
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6YV5
 | | Crystal Structure of Serine protease SplB N3Q/S154R from Staphylococcus aureus | | 分子名称: | SODIUM ION, Serine protease | | 著者 | Rangel Pereira, M.R, Brear, P, Knyphausen, P, Jermutus, L, Hollfelder, F. | | 登録日 | 2020-04-27 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Crystal Structure of Serine protease SplB N3Q/S154R from Staphylococcus aureus
To Be Published
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6YV6
 | | Crystal Structure of Serine protease SplB N2K/N3Q/S154R from Staphylococcus aureus | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Serine protease | | 著者 | Rangel Pereira, M.R, Brear, P, Knyphausen, P, Jermutus, L, Hollfelder, F. | | 登録日 | 2020-04-27 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Crystal Structure of Serine protease SplB N2K/N3Q/S154R from Staphylococcus aureus
to be published
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4HJ0
 | | Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution | | 分子名称: | Gastric inhibitory polypeptide receptor, Gipg013 Fab, Antagonizing antibody to the GIP Receptor, ... | | 著者 | Madhurantakam, C, Ravn, P, Gruetter, M.G, Jackson, R.H. | | 登録日 | 2012-10-12 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor.
J.Biol.Chem., 288, 2013
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3TJE
 | | Crystal structure of Fas receptor extracellular domain in complex with Fab E09 | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | | 登録日 | 2011-08-24 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
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6BFT
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6BGT
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3THM
 | | Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ... | | 著者 | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | | 登録日 | 2011-08-19 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
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3EO1
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3EO0
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1P4B
 | | Three-Dimensional Structure Of a Single Chain Fv Fragment Complexed With The peptide GCN4(7P-14P). | | 分子名称: | Antibody Variable heavy chain, Antibody Variable light chain, GCN4(7P-14P) peptide | | 著者 | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | | 登録日 | 2003-04-22 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
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1P4I
 | | Crystal Structure of scFv against peptide GCN4 | | 分子名称: | ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain | | 著者 | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | | 登録日 | 2003-04-23 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
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