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High-resolution structure of the cemiplimab Fab in complex with PD-1
Descriptor:	Programmed cell death protein 1, heavy chain, light chain
Authors:	Heo, Y.-S, Jeong, T.J.
Deposit date:	2022-09-21
Release date:	2023-10-04
Method:	X-RAY DIFFRACTION (1.98 Å)
Cite:	High-resolution structure of the cemiplimab Fab in complex with PD-1 To Be Published

PD-1 in complex with Dostarlimab
Descriptor:	Programmed cell death protein 1, heavy chain, light chain
Authors:	Heo, Y.S.
Deposit date:	2022-01-30
Release date:	2022-08-24
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.534 Å)
Cite:	Molecular basis of PD-1 blockade by dostarlimab, the FDA-approved antibody for cancer immunotherapy. Biochem.Biophys.Res.Commun., 599, 2022

crystal structure of CD38 in complex with daratumumab
Descriptor:	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy Chain, Light chain
Authors:	Lee, H.T, Heo, Y.S.
Deposit date:	2020-11-13
Release date:	2021-09-22
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.55 Å)
Cite:	Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma. Biochem.Biophys.Res.Commun., 536, 2021

High-resolution structure of vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine
Descriptor:	caplacizumab, von Willebrand factor
Authors:	Lee, H.T, Heo, Y.-S.
Deposit date:	2021-04-23
Release date:	2021-07-07
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	High-resolution structure of the vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine for treating acquired TTP. Biochem.Biophys.Res.Commun., 567, 2021