7WSL

PD-1 in complex with Dostarlimab

Summary for 7WSL

Entry DOI	10.2210/pdb7wsl/pdb
Descriptor	light chain, Programmed cell death protein 1, heavy chain, ... (4 entities in total)
Functional Keywords	pd-1, dostarlimab, antibody, cancer immunotherapy, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	62804.76
Authors	Heo, Y.S. (deposition date: 2022-01-30, release date: 2022-08-24, Last modification date: 2023-11-29)
Primary citation	Park, U.B.,Jeong, T.J.,Gu, N.,Lee, H.T.,Heo, Y.S. Molecular basis of PD-1 blockade by dostarlimab, the FDA-approved antibody for cancer immunotherapy. Biochem.Biophys.Res.Commun., 599:31-37, 2022 Cited by PubMed: 35168061 DOI: 10.1016/j.bbrc.2022.02.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.534 Å)

Structure validation