7WSL
PD-1 in complex with Dostarlimab
Summary for 7WSL
Entry DOI | 10.2210/pdb7wsl/pdb |
Descriptor | light chain, Programmed cell death protein 1, heavy chain, ... (4 entities in total) |
Functional Keywords | pd-1, dostarlimab, antibody, cancer immunotherapy, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 62804.76 |
Authors | Heo, Y.S. (deposition date: 2022-01-30, release date: 2022-08-24, Last modification date: 2023-11-29) |
Primary citation | Park, U.B.,Jeong, T.J.,Gu, N.,Lee, H.T.,Heo, Y.S. Molecular basis of PD-1 blockade by dostarlimab, the FDA-approved antibody for cancer immunotherapy. Biochem.Biophys.Res.Commun., 599:31-37, 2022 Cited by PubMed: 35168061DOI: 10.1016/j.bbrc.2022.02.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.534 Å) |
Structure validation
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