6C21
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6BTM
| Structure of Alternative Complex III from Flavobacterium johnsoniae (Wild Type) | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, Alternative Complex III subunit A, Alternative Complex III subunit B, ... | Authors: | Sun, C, Benlekbir, S, Venkatakrishnan, P, Yuhang, W, Tajkhorshid, E, Rubinstein, J.L, Gennis, R.B. | Deposit date: | 2017-12-07 | Release date: | 2018-05-09 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the alternative complex III in a supercomplex with cytochrome oxidase. Nature, 557, 2018
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6C7Q
| BRD4 BD2 in complex with compound CE277 | Descriptor: | 7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-2-methyl-N-(1-methyl-1H-indazol-3-yl)-9H-pyrimido[4,5-b]indol-4-amine, Bromodomain-containing protein 4 | Authors: | Meagher, J.L, Stuckey, J.A. | Deposit date: | 2018-01-23 | Release date: | 2018-08-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor. J. Med. Chem., 61, 2018
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2ATC
| CRYSTAL AND MOLECULAR STRUCTURES OF NATIVE AND CTP-LIGANDED ASPARTATE CARBAMOYLTRANSFERASE FROM ESCHERICHIA COLI | Descriptor: | ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, REGULATORY CHAIN, ... | Authors: | Honzatko, R.B, Crawford, J.L, Monaco, H.L, Ladner, J.E, Edwards, B.F.P, Evans, D.R, Warren, S.G, Wiley, D.C, Ladner, R.C, Lipscomb, W.N. | Deposit date: | 1982-03-24 | Release date: | 1982-12-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli. J.Mol.Biol., 160, 1982
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1A9U
| THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580 | Descriptor: | 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, MAP KINASE P38 | Authors: | Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J. | Deposit date: | 1998-04-10 | Release date: | 1999-04-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of inhibitor selectivity in MAP kinases. Structure, 6, 1998
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1A1R
| HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX | Descriptor: | NS3 PROTEIN, NS4A PROTEIN, ZINC ION | Authors: | Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A. | Deposit date: | 1997-12-15 | Release date: | 1998-06-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell(Cambridge,Mass.), 87, 1996
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1AMN
| TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE | Descriptor: | ACETYLCHOLINESTERASE, M-(N,N,N-TRIMETHYLAMMONIO)-2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYLBENZENE, SULFATE ION | Authors: | Harel, M, Silman, I, Sussman, J.L. | Deposit date: | 1996-02-13 | Release date: | 1996-04-03 | Last modified: | 2021-06-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase. J.Am.Chem.Soc., 118, 1996
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1AZW
| PROLINE IMINOPEPTIDASE FROM XANTHOMONAS CAMPESTRIS PV. CITRI | Descriptor: | PROLINE IMINOPEPTIDASE | Authors: | Medrano, F.J, Alonso, J, Garcia, J.L, Romero, A, Bode, W, Gomis-Ruth, F.X. | Deposit date: | 1997-11-22 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family. EMBO J., 17, 1998
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1B41
| HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH FASCICULIN-II, GLYCOSYLATED PROTEIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Kryger, G, Harel, M, Shafferman, A, Silman, I, Sussman, J.L. | Deposit date: | 1999-01-05 | Release date: | 2001-01-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II. Acta Crystallogr.,Sect.D, 56, 2000
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1BF6
| PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHOSPHOTRIESTERASE HOMOLOGY PROTEIN, ... | Authors: | Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J. | Deposit date: | 1998-05-27 | Release date: | 1999-06-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family. Biochemistry, 37, 1998
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1BGX
| TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB | Descriptor: | TAQ DNA POLYMERASE, TP7 MAB | Authors: | Murali, R, Sharkey, D.J, Daiss, J.L, Krishna Murthy, H.M. | Deposit date: | 1998-06-02 | Release date: | 1998-10-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. Proc.Natl.Acad.Sci.USA, 95, 1998
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1BCE
| INTRAMOLECULAR TRIPLEX, NMR, 10 STRUCTURES | Descriptor: | DNA (5'-D(*AP*AP*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*T)-3') | Authors: | Asensio, J.L, Brown, T, Lane, A.N. | Deposit date: | 1998-04-29 | Release date: | 1998-08-12 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Comparison of the solution structures of intramolecular DNA triple helices containing adjacent and non-adjacent CG.C+ triplets. Nucleic Acids Res., 26, 1998
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1BMK
| THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655 | Descriptor: | 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE, PROTEIN (MAP KINASE P38) | Authors: | Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J. | Deposit date: | 1998-07-23 | Release date: | 1999-07-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of inhibitor selectivity in MAP kinases. Structure, 6, 1998
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1BL6
| THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995 | Descriptor: | 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38) | Authors: | Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J. | Deposit date: | 1998-07-11 | Release date: | 1999-07-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of inhibitor selectivity in MAP kinases. Structure, 6, 1998
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1BL7
| THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025 | Descriptor: | 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38) | Authors: | Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J. | Deposit date: | 1998-07-23 | Release date: | 1999-07-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of inhibitor selectivity in MAP kinases. Structure, 6, 1998
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1BRZ
| SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZZEIN, NMR, 43 STRUCTURES | Descriptor: | BRAZZEIN | Authors: | Caldwell, J.E, Abildgaard, F, Dzakula, Z, Ming, D, Hellekant, G, Markley, J.L. | Deposit date: | 1998-03-12 | Release date: | 1998-07-01 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Solution structure of the thermostable sweet-tasting protein brazzein. Nat.Struct.Biol., 5, 1998
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1BL0
| MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*TP*GP*CP*CP*AP*CP*GP*TP*TP*TP*TP*GP*CP*TP*AP*AP*AP*TP* CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*TP*AP*GP*CP*AP*AP*AP*AP*CP*GP*TP*GP*GP*CP*AP* TP*C)-3'), PROTEIN (MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN) | Authors: | Davies, S, Rhee, R.G, Martin, J.L, Rosner, D.R. | Deposit date: | 1998-07-22 | Release date: | 1998-09-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator. Proc.Natl.Acad.Sci.USA, 95, 1998
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1BOS
| SHIGA-LIKE TOXIN COMPLEXED WITH ITS RECEPTOR | Descriptor: | SHIGA-LIKE TOXIN I B SUBUNIT, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Ling, H, Boodhoo, A, Hazes, B, Cummings, M.D, Armstrong, G.D, Brunton, J.L, Read, R.J. | Deposit date: | 1998-01-13 | Release date: | 1999-02-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3. Biochemistry, 37, 1998
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1C48
| MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T) | Descriptor: | PROTEIN (SHIGA-LIKE TOXIN I B SUBUNIT) | Authors: | Ling, H, Bast, D, Brunton, J.L, Read, R.J. | Deposit date: | 1999-08-11 | Release date: | 2000-08-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate To be Published
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1C4Q
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1CI3
| CYTOCHROME F FROM THE B6F COMPLEX OF PHORMIDIUM LAMINOSUM | Descriptor: | HEME C, PROTEIN (CYTOCHROME F), ZINC ION | Authors: | Carrell, C.J, Schlarb, B.G, Howe, C.J, Bendall, D.S, Cramer, W.A, Smith, J.L. | Deposit date: | 1999-04-07 | Release date: | 1999-08-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the soluble domain of cytochrome f from the cyanobacterium Phormidium laminosum. Biochemistry, 38, 1999
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1CFJ
| METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH O-ISOPROPYLMETHYLPHOSPHONOFLUORIDATE (GB, SARIN) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, METHYLPHOSPHONIC ACID ESTER GROUP, PROTEIN (ACETYLCHOLINESTERASE) | Authors: | Millard, C.B, Silman, I, Sussman, J.L. | Deposit date: | 1999-03-19 | Release date: | 1999-06-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level. Biochemistry, 38, 1999
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1CTM
| CRYSTAL STRUCTURE OF CHLOROPLAST CYTOCHROME F REVEALS A NOVEL CYTOCHROME FOLD AND UNEXPECTED HEME LIGATION | Descriptor: | CYTOCHROME F, HEME C | Authors: | Martinez, S.E, Huang, D, Szczepaniak, A, Cramer, W.A, Smith, J.L. | Deposit date: | 1994-01-02 | Release date: | 1994-05-31 | Last modified: | 2021-03-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of chloroplast cytochrome f reveals a novel cytochrome fold and unexpected heme ligation. Structure, 2, 1994
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3OB6
| Structure of AdiC(N101A) in the open-to-out Arg+ bound conformation | Descriptor: | ARGININE, AdiC arginine:agmatine antiporter | Authors: | Carpena, X, Kowalczyk, L, Ratera, M, Valencia, E, Vazquez-lbar, J.L, Fita, I, Palacin, M. | Deposit date: | 2010-08-06 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular basis of substrate-induced permeation by an amino acid antiporter. Proc.Natl.Acad.Sci.USA, 108, 2011
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8A43
| Human RNA polymerase I | Descriptor: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | Authors: | Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. | Deposit date: | 2022-06-10 | Release date: | 2022-08-31 | Last modified: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (4.09 Å) | Cite: | The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. Life Sci Alliance, 5, 2022
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