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6Y2N
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BU of 6y2n by Molmil
Crystal structure of ribonucleotide reductase R2 subunit solved by serial synchrotron crystallography
分子名称: FE (III) ION, MANGANESE (III) ION, Ribonucleoside-diphosphate reductase subunit beta
著者Shilova, A, Lebrette, H, Aurelius, O, Hogbom, M, Mueller, U.
登録日2020-02-17
公開日2020-10-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
7Z3E
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BU of 7z3e by Molmil
XFEL structure of Class Ib ribonucleotide reductase dimanganese(II) NrdF in complex with hydroquinone NrdI from Bacillus cereus
分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, MANGANESE (II) ION, Protein NrdI, ...
著者John, J, Lebrette, H, Aurelius, O, Hogbom, M.
登録日2022-03-02
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography.
Elife, 11, 2022
7Z3D
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XFEL structure of Class Ib ribonucleotide reductase dimanganese(II) NrdF in complex with oxidized NrdI from Bacillus cereus
分子名称: FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein NrdI, ...
著者John, J, Lebrette, H, Aurelius, O, Hogbom, M.
登録日2022-03-02
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography.
Elife, 11, 2022
1RSV
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BU of 1rsv by Molmil
azide complex of the diferrous E238A mutant R2 subunit of ribonucleotide reductase
分子名称: AZIDE ION, FE (III) ION, MERCURY (II) ION, ...
著者Assarsson, M, Andersson, M.E, Hogbom, M, Persson, B.O, Sahlin, M, Barra, A.L, Sjoberg, B.M, Nordlund, P, Graslund, A.
登録日2003-12-10
公開日2003-12-23
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli.
J.Biol.Chem., 276, 2001
5N77
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BU of 5n77 by Molmil
Crystal structure of the cytosolic domain of the CorA magnesium channel from Escherichia coli in complex with magnesium
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, Magnesium transport protein CorA
著者Lerche, M, Sandhu, H, Flockner, L, Hogbom, M, Rapp, M.
登録日2017-02-20
公開日2017-07-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and Cooperativity of the Cytosolic Domain of the CorA Mg(2+) Channel from Escherichia coli.
Structure, 25, 2017
7QBK
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BU of 7qbk by Molmil
Crystal structure of a second homolog of R2-like ligand-binding oxidase in Sulfolobus acidocaldarius (SaR2loxII)
分子名称: FE (III) ION, MANGANESE (III) ION, R2-like ligand-binding oxidase (homolog II) from Sulfolobus acidocaldarius
著者Lebrette, H, Diamanti, R, Srinivas, V, Hogbom, M.
登録日2021-11-19
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.
Febs Lett., 596, 2022
5MLK
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BU of 5mlk by Molmil
Biotin dependent carboxylase AccA3 dimer from Mycobacterium tuberculosis (Rv3285)
分子名称: Acetyl-COA carboxylase
著者Bennett, M.D, Hogbom, M.
登録日2016-12-07
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.939 Å)
主引用文献Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis.
FEBS Open Bio, 7, 2017
8BHW
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BU of 8bhw by Molmil
Full-length bacterial polysaccharide co-polymerase WzzE from E. coli. C4 symmetry
分子名称: ECA polysaccharide chain length modulation protein
著者Wiseman, B, Hogbom, M.
登録日2022-11-01
公開日2023-07-26
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Alternating L4 loop architecture of the bacterial polysaccharide co-polymerase WzzE.
Commun Biol, 6, 2023
8BT4
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Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, radical-lost ground state
分子名称: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase
著者Lebrette, H, Srinivas, V, Hogbom, M.
登録日2022-11-27
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of a ribonucleotide reductase R2 protein radical.
Science, 382, 2023
8BT3
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Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, catalytically active radical state solved by XFEL
分子名称: Ribonucleoside-diphosphate reductase beta chain
著者Lebrette, H, Srinivas, V, Hogbom, M.
登録日2022-11-27
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of a ribonucleotide reductase R2 protein radical.
Science, 382, 2023
3GZD
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BU of 3gzd by Molmil
Human selenocysteine lyase, P1 crystal form
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, NITRATE ION, Selenocysteine lyase
著者Karlberg, T, Hogbom, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日2009-04-07
公開日2009-04-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.
Plos One, 7, 2012
3GZC
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BU of 3gzc by Molmil
Structure of human selenocysteine lyase
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Selenocysteine lyase
著者Collins, R, Hogbom, M, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Karlberg, T, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Schuler, H, Structural Genomics Consortium (SGC)
登録日2009-04-07
公開日2009-04-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.
Plos One, 7, 2012
2UW2
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BU of 2uw2 by Molmil
Crystal structure of human ribonucleotide reductase subunit R2
分子名称: FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT
著者Welin, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Stenmark, P, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2007-03-16
公開日2007-04-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
2UVQ
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BU of 2uvq by Molmil
Crystal structure of human uridine-cytidine kinase 1 in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, URIDINE-CYTIDINE KINASE 1
著者Kosinska, U, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E.P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Uppsten, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P.
登録日2007-03-13
公開日2007-03-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Human Uridine-Cytidine Kinase 1
To be Published
4B4A
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BU of 4b4a by Molmil
Structure of the TatC core of the twin arginine protein translocation system
分子名称: Lauryl Maltose Neopentyl Glycol, SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC
著者Rollauer, S.E, Tarry, M.J, Jaaskelainen, M, Graham, J.E, Jaeger, F, Krehenbrink, M, Roversi, P, McDowell, M.A, Stansfeld, P.J, Johnson, S, Liu, S.M, Lukey, M.J, Marcoux, J, Robinson, C.V, Sansom, M.S, Palmer, T, Hogbom, M, Berks, B.C, Lea, S.M.
登録日2012-07-30
公開日2012-12-05
最終更新日2012-12-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Tatc Core of the Twin-Arginine Protein Transport System.
Nature, 49, 2012
2RB4
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BU of 2rb4 by Molmil
Crystal structure of the Helicase domain of human DDX25 RNA helicase
分子名称: ATP-dependent RNA helicase DDX25, CHLORIDE ION, SULFATE ION, ...
著者Lehtio, L, Hogbom, M, Uppenberg, J, Arrowsmith, C.H, Berglund, H, Edwards, A.M, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-09-18
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
4HR4
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BU of 4hr4 by Molmil
R2-like ligand-binding oxidase with anaerobically reconstituted metal cofactor
分子名称: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
著者Griese, J.J, Hogbom, M.
登録日2012-10-26
公開日2013-10-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
4HR5
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BU of 4hr5 by Molmil
R2-like ligand-binding oxidase without metal cofactor
分子名称: PALMITIC ACID, Ribonuleotide reductase small subunit
著者Griese, J.J, Hogbom, M.
登録日2012-10-26
公開日2013-10-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
4HR0
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BU of 4hr0 by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted metal cofactor
分子名称: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
著者Griese, J.J, Hogbom, M.
登録日2012-10-26
公開日2013-10-16
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (1.896 Å)
主引用文献Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
1RSR
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azide complex of the diferrous F208A mutant R2 subunit of ribonucleotide reductase
分子名称: AZIDE ION, FE (II) ION, MERCURY (II) ION, ...
著者Andersson, M.E, Hogbom, M, Rinaldo-Matthis, A, Andersson, K.K, Sjoberg, B.M, Nordlund, P.
登録日2003-12-10
公開日2003-12-23
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of an Azide Complex of the Diferrous R2 Subunit of Ribonucleotide Reductase Displays a Novel Carboxylate Shift with Important Mechanistic Implications for Diiron-Catalyzed Oxygen Activation
J.Am.Chem.Soc., 121, 1999
3ZR0
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BU of 3zr0 by Molmil
Crystal structure of human MTH1 in complex with 8-oxo-dGMP
分子名称: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION
著者Svensson, L.M, Jemth, A, Desroses, M, Loseva, O, Helleday, T, Hogbom, M, Stenmark, P.
登録日2011-06-13
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Human Mth1 and the 8-Oxo-Dgmp Product Complex.
FEBS Lett., 585, 2011
3ZR1
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Crystal structure of human MTH1
分子名称: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, SULFATE ION
著者Svensson, L.M, Jemth, A, Desroses, M, Loseva, O, Helleday, T, Hogbom, M, Stenmark, P.
登録日2011-06-13
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Human Mth1 and the 8-Oxo-Dgmp Product Complex.
FEBS Lett., 585, 2011
5EKB
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BU of 5ekb by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted Mn/Fe cofactor (reconstituted in solution)
分子名称: FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ...
著者Griese, J.J, Hogbom, M.
登録日2015-11-03
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins.
J.Inorg.Biochem., 162, 2016
5DCR
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BU of 5dcr by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted Mn/Fe cofactor (short soak)
分子名称: FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ...
著者Griese, J.J, Hogbom, M.
登録日2015-08-24
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.108 Å)
主引用文献Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
J.Biol.Chem., 290, 2015
6YD0
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XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, diferric state
分子名称: FE (III) ION, GLYCEROL, Methane monooxygenase, ...
著者Srinivas, V, Hogbom, M.
登録日2020-03-19
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
J. Am. Chem. Soc., 142, 2020

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