3ZR0

Crystal structure of human MTH1 in complex with 8-oxo-dGMP

Summary for 3ZR0

Entry DOI	10.2210/pdb3zr0/pdb
Related	1IRY 3ZR1
Descriptor	7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ... (4 entities in total)
Functional Keywords	hydrolase, dna repair
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	37149.68
Authors	Svensson, L.M.,Jemth, A.,Desroses, M.,Loseva, O.,Helleday, T.,Hogbom, M.,Stenmark, P. (deposition date: 2011-06-13, release date: 2011-07-27, Last modification date: 2023-12-20)
Primary citation	Svensson, L.M.,Jemth, A.,Desroses, M.,Loseva, O.,Helleday, T.,Hogbom, M.,Stenmark, P. Crystal Structure of Human Mth1 and the 8-Oxo-Dgmp Product Complex. FEBS Lett., 585:2617-, 2011 Cited by PubMed: 21787772 DOI: 10.1016/J.FEBSLET.2011.07.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation