2B48
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![BU of 2b48 by Molmil](/molmil-images/mine/2b48) | |
1R2G
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![BU of 1r2g by Molmil](/molmil-images/mine/1r2g) | Human Bcl-XL containing a Phe to Trp mutation at position 97 | Descriptor: | Apoptosis regulator Bcl-X | Authors: | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | Deposit date: | 2003-09-26 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2E
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![BU of 1r2e by Molmil](/molmil-images/mine/1r2e) | Human Bcl-XL containing a Glu to Leu mutation at position 92 | Descriptor: | Apoptosis regulator Bcl-X | Authors: | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | Deposit date: | 2003-09-26 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2I
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![BU of 1r2i by Molmil](/molmil-images/mine/1r2i) | Human Bcl-XL containing a Phe to Leu mutation at position 146 | Descriptor: | Apoptosis regulator Bcl-X | Authors: | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | Deposit date: | 2003-09-26 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2H
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![BU of 1r2h by Molmil](/molmil-images/mine/1r2h) | Human Bcl-XL containing an Ala to Leu mutation at position 142 | Descriptor: | Apoptosis regulator Bcl-X | Authors: | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | Deposit date: | 2003-09-26 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2D
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![BU of 1r2d by Molmil](/molmil-images/mine/1r2d) | Structure of Human Bcl-XL at 1.95 Angstroms | Descriptor: | Apoptosis regulator Bcl-X | Authors: | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | Deposit date: | 2003-09-26 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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5JSN
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![BU of 5jsn by Molmil](/molmil-images/mine/5jsn) | Bcl2-inhibitor complex | Descriptor: | Apoptosis regulator Bcl-2, Bcl2 inhibitor | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2016-05-09 | Release date: | 2016-11-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Elife, 5, 2016
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5JSB
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![BU of 5jsb by Molmil](/molmil-images/mine/5jsb) | Crystal structure of Mcl1-inhibitor complex | Descriptor: | Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 inhibitor | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2016-05-07 | Release date: | 2016-11-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Elife, 5, 2016
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4OYD
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![BU of 4oyd by Molmil](/molmil-images/mine/4oyd) | Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein | Descriptor: | 1,2-ETHANEDIOL, Apoptosis regulator BHRF1, Computationally designed Inhibitor | Authors: | Shen, B, Procko, E, Baker, D, Stoddard, B. | Deposit date: | 2014-02-11 | Release date: | 2014-07-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A computationally designed inhibitor of an epstein-barr viral bcl-2 protein induces apoptosis in infected cells. Cell, 157, 2014
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