2B48

Bcl-XL 3D Domain Swapped Dimer

Summary for 2B48

Entry DOI	10.2210/pdb2b48/pdb
Related	1MAZ 1R2D
Descriptor	Apoptosis regulator Bcl-X (1 entity in total)
Functional Keywords	apoptosis, dimeric, 3d domain swap, alpha-helical, apoptosis inhibitor
Biological source	Homo sapiens (human)
Cellular location	Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817
Total number of polymer chains	1
Total formula weight	24606.94
Authors	O'Neill, J.W.,Manion, M.K.,Maguire, B.,Hockenbery, D.M. (deposition date: 2005-09-22, release date: 2006-02-14, Last modification date: 2023-08-23)
Primary citation	O'Neill, J.W.,Manion, M.K.,Maguire, B.,Hockenbery, D.M. BCL-X(L) Dimerization by Three-dimensional Domain Swapping. J.Mol.Biol., 356:367-381, 2006 Cited by PubMed: 16368107 DOI: 10.1016/j.jmb.2005.11.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.45 Å)

Structure validation