7QSO
| Bovine complex I in lipid nanodisc, State 3 (Slack) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSN
| Bovine complex I in lipid nanodisc, Deactive-apo | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSL
| Bovine complex I in lipid nanodisc, Active-apo | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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8CA4
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2 N-domain). | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA5
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3). | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA1
| Cryo-EM structure of the ACADVL dimer from Mus musculus. | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA3
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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5LDX
| Structure of mammalian respiratory Complex I, class3. | 分子名称: | Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Vinothkumar, K.R, Zhu, J, Hirst, J. | 登録日 | 2016-06-28 | 公開日 | 2016-09-14 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structure of mammalian respiratory complex I. Nature, 536, 2016
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5LC5
| Structure of mammalian respiratory Complex I, class2 | 分子名称: | Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Vinothkumar, K.R, Zhu, J, Hirst, J. | 登録日 | 2016-06-19 | 公開日 | 2016-09-07 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | 主引用文献 | Structure of mammalian respiratory complex I. Nature, 536, 2016
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5LDW
| Structure of mammalian respiratory Complex I, class1 | 分子名称: | Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Vinothkumar, K.R, Zhu, J, Hirst, J. | 登録日 | 2016-06-28 | 公開日 | 2016-09-07 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | Structure of mammalian respiratory complex I. Nature, 536, 2016
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1D3W
| Crystal structure of ferredoxin 1 d15e mutant from azotobacter vinelandii at 1.7 angstrom resolution. | 分子名称: | FE3-S4 CLUSTER, FERREDOXIN 1, IRON/SULFUR CLUSTER | 著者 | Chen, K, Hirst, J, Camba, R, Bonagura, C.A, Stout, C.D, Burges, B.K, Armstrong, F.A. | 登録日 | 1999-10-01 | 公開日 | 1999-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Atomically defined mechanism for proton transfer to a buried redox centre in a protein. Nature, 405, 2000
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1NA8
| Crystal structure of ADP-ribosylation factor binding protein GGA1 | 分子名称: | ADP-ribosylation factor binding protein GGA1 | 著者 | Lui, W.W, Collins, B.M, Hirst, J, Motley, A, Millar, C, Schu, P, Owen, D.J, Robinson, M.S. | 登録日 | 2002-11-27 | 公開日 | 2003-07-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin Mol.Cell.Biol., 14, 2003
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1NYK
| Crystal Structure of the Rieske protein from Thermus thermophilus | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, MAGNESIUM ION, Rieske iron-sulfur protein | 著者 | Hunsicker-Wang, L.M, Heine, A, Chen, Y, Luna, E.P, Todaro, T, Zhang, Y.M, Williams, P.A, McRee, D.E, Hirst, J, Stout, C.D, Fee, J.A. | 登録日 | 2003-02-12 | 公開日 | 2003-06-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | High resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: Analysis and Comparison Biochemistry, 42, 2003
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8BA0
| Drosophila melanogaster complex I in the Twisted state (Dm2) | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | 著者 | Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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8B9Z
| Drosophila melanogaster complex I in the Active state (Dm1) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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6G2J
| Mouse mitochondrial complex I in the active state | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Agip, A.N.A, Blaza, J.N, Bridges, H.R, Viscomi, C, Rawson, S, Muench, S.P, Hirst, J. | 登録日 | 2018-03-23 | 公開日 | 2018-06-06 | 最終更新日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states. Nat. Struct. Mol. Biol., 25, 2018
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7R42
| Bovine complex I in the presence of IM1761092, active class ii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R41
| Bovine complex I in the presence of IM1761092, active class i (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R45
| Bovine complex I in the presence of IM1761092, deactive class i (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R47
| Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R44
| Bovine complex I in the presence of IM1761092, active class iv (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R48
| Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R4F
| Bovine complex I in the presence of IM1761092, slack class i (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R46
| Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R4C
| Bovine complex I in the presence of IM1761092, deactive class v (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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