8CA4
Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2 N-domain).
Summary for 8CA4
| Entry DOI | 10.2210/pdb8ca4/pdb |
| Related | 8C2S 8CA1 8CA3 |
| EMDB information | 16517 |
| Descriptor | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial, NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, ... (8 entities in total) |
| Functional Keywords | nadh ubiquinone oxidoreductase, complex i, oxidoreductase |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 5 |
| Total formula weight | 182718.26 |
| Authors | Yin, Z.,Bridges, H.R.,Agip, A.N.A.,Hirst, J. (deposition date: 2023-01-24, release date: 2023-12-20, Last modification date: 2024-01-31) |
| Primary citation | Yin, Z.,Agip, A.A.,Bridges, H.R.,Hirst, J. Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43:225-249, 2024 Cited by PubMed: 38177503DOI: 10.1038/s44318-023-00001-4 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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