8CA4
Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2 N-domain).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 248 | 27318.3 | 1 | UniProt (Q9D6J6) Pfam (PF01257) | Mus musculus (house mouse) | NADH-ubiquinone oxidoreductase 24 kDa subunit |
| 2 | B (F) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 464 | 50904.2 | 1 | UniProt (Q91YT0) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Mus musculus (house mouse) | Complex I-51kD,CI-51kD,NADH-ubiquinone oxidoreductase 51 kDa subunit |
| 3 | C (G) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 727 | 79866.7 | 1 | UniProt (Q91VD9) Pfam (PF09326) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) | Mus musculus (house mouse) | Complex I-75kD,CI-75kD |
| 4 | D (S) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 99 | 10932.7 | 1 | UniProt (Q9CQ75) Pfam (PF05047) | Mus musculus (house mouse) | Complex I-B8,CI-B8,NADH-ubiquinone oxidoreductase B8 subunit |
| 5 | E (s) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 104 | 11833.5 | 1 | UniProt (Q8BK30) Pfam (PF15880) | Mus musculus (house mouse) | Complex I-9kD,CI-9kD,NADH-ubiquinone oxidoreductase 9 kDa subunit |
| 6 | F, K (E, G) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 7 | G, I, J (F, G) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 3 | Chemie (SF4) | |||
| 8 | H (F) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (23585816) PubChem (643976) PubChem (51435500) PubChem (51435503) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (15559251) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 180855.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1862.9 | |
| All* | Total formula weight | 182718.3 |
