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5EOS
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BU of 5eos by Molmil
Crystallizing Strained DNA: Self-Assembly of 3D Crystals Containing a Torsionally-Stressed Component
Descriptor: DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*TP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*AP*CP*CP*GP*T)-3'), ...
Authors:Hernandez, C, Birktoft, J.J, Seeman, N.C.
Deposit date:2015-11-10
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4.7 Å)
Cite:Self-Assembly of 3D DNA Crystals Containing a Torsionally Stressed Component.
Cell Chem Biol, 2017
5W6W
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BU of 5w6w by Molmil
Designing Higher Resolution Self-Assembled 3D DNA Crystals via Strand Terminus Modifications
Descriptor: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ...
Authors:Hernandez, C, Birktoft, J.J, Seeman, N.C.
Deposit date:2017-06-17
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Designing Higher Resolution Self-Assembled 3D DNA Crystals via Strand Terminus Modifications
To Be Published
9GS2
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BU of 9gs2 by Molmil
Structure of the Rieske bound Apo1 state of the heptameric Bcs1 AAA-ATPase
Descriptor: Cytochrome b-c1 complex subunit Rieske, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Rosales-Hernandez, C, Beckmann, R.
Deposit date:2024-09-13
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Mechanistic insights into Bcs1-mediated mitochondrial membrane translocation of the folded Rieske protein.
Embo J., 2025
9GSN
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BU of 9gsn by Molmil
Structure of the ATPgS-S1 state of the heptameric Bcs1 AAA-ATPase
Descriptor: Mitochondrial chaperone BCS1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Rosales-Hernandez, C, Beckmann, R.
Deposit date:2024-09-16
Release date:2025-06-04
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Mechanistic insights into Bcs1-mediated mitochondrial membrane translocation of the folded Rieske protein.
Embo J., 2025
9GU9
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BU of 9gu9 by Molmil
Structure of the ATPgS-S2 state of the heptameric Bcs1 AAA-ATPase
Descriptor: Mitochondrial chaperone BCS1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Rosales-Hernandez, C, Beckmann, R.
Deposit date:2024-09-19
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Mechanistic insights into Bcs1-mediated mitochondrial membrane translocation of the folded Rieske protein.
Embo J., 2025
8UY5
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BU of 8uy5 by Molmil
[ZP] Self-assembling DNA crystal with expanded genetic code using C,A,T,G, Z and P nucleotides
Descriptor: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*(DP)P*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*(DZ)P*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ...
Authors:Vecchioni, S, Sha, R, Ohayon, Y.P, Hernandez, C.
Deposit date:2023-11-13
Release date:2025-01-22
Method:X-RAY DIFFRACTION (3.562 Å)
Cite:Six-Letter DNA Nanotechnology: Incorporation of Z - P Base Pairs into Self-Assembling 3D Crystals.
Nano Lett., 24, 2024
6EU6
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BU of 6eu6 by Molmil
Sensor Amt Protein
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AMMONIUM ION, Ammonium transporter, ...
Authors:Pflueger, T, Hernandez, C, Andrade, S.L.A.
Deposit date:2017-10-28
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Signaling ammonium across membranes through an ammonium sensor histidine kinase.
Nat Commun, 9, 2018
8WKZ
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BU of 8wkz by Molmil
Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with S31
Descriptor: CALCIUM ION, Melanocortin receptor 4, OLEIC ACID, ...
Authors:Gimenez, L.E, Martin, C, Yu, J, Hollanders, C, Hernandez, C, Dahir, N.S, Wu, Y, Yao, D, Han, G.W, Wu, L, Poorten, O.V, Lamouroux, A, Mannes, M, Tourwe, D, Zhao, S, Stevens, R.C, Cone, R.D, Ballet, S.
Deposit date:2023-09-28
Release date:2024-08-07
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design.
J.Med.Chem., 67, 2024
8WKY
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BU of 8wky by Molmil
Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with S25
Descriptor: CALCIUM ION, Melanocortin receptor 4, N-(2-aminoethyl)-5-(2-{[4-(morpholin-4-yl)pyridin-2-yl]amino}-1,3-thiazol-5-yl)pyridine-3-carboxamide, ...
Authors:Gimenez, L.E, Martin, C, Yu, J, Hollanders, C, Hernandez, C, Dahir, N.S, Wu, Y, Yao, D, Han, G.W, Wu, L, Poorten, O.V, Lamouroux, A, Mannes, M, Tourwe, D, Zhao, S, Stevens, R.C, Cone, R.D, Ballet, S.
Deposit date:2023-09-28
Release date:2024-08-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design.
J.Med.Chem., 67, 2024
9NAA
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BU of 9naa by Molmil
Unusual structure of a bacteriophytochrome fragment derived from full length SaBphP2
Descriptor: 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, histidine kinase
Authors:Schmidt, M, Prabin, K.
Deposit date:2025-02-11
Release date:2025-05-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of myxobacterial phytochrome revealed by cryo-EM using the Spotiton technique and with x-ray crystallography.
Struct Dyn., 12, 2025
9H80
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BU of 9h80 by Molmil
Structure of the outer membrane exopolysaccharide transporter PelBC
Descriptor: PHOSPHATIDYLETHANOLAMINE, PelB, PelC
Authors:Benedens, M, Rosales, C, Beckmann, R, Kedrov, A.
Deposit date:2024-10-28
Release date:2025-06-11
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa.
Nat Commun, 16, 2025
7P0M
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BU of 7p0m by Molmil
Human mitochondrial Lon protease with substrate in the ATPase and protease domains
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-30
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P09
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BU of 7p09 by Molmil
Human mitochondrial Lon protease with substrate in the ATPase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-29
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P0B
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BU of 7p0b by Molmil
Human mitochondrial Lon protease without substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-29
Release date:2021-08-11
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
5I36
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BU of 5i36 by Molmil
Crystal structure of color device state A
Descriptor: DNA (26-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*GP*TP*GP*GP*TP*AP*TP*C)-3'), DNA (5'-D(*CP*AP*GP*AP*TP*AP*CP*CP*TP*GP*AP*TP*CP*GP*GP*AP*CP*TP*AP*CP*G)-3'), ...
Authors:Hao, Y, Kristiansen, M, Sha, R, Birktoft, J, Mao, C, Seeman, N.C.
Deposit date:2016-02-09
Release date:2017-01-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (5.123 Å)
Cite:A device that operates within a self-assembled 3D DNA crystal.
Nat Chem, 9, 2017
5KEK
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BU of 5kek by Molmil
Structure Determination of a Self-Assembling DNA Crystal
Descriptor: CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*GP*T)-3'), ...
Authors:Simmons, C.R, Birktoft, J.J, Seeman, N.C, Yan, H.
Deposit date:2016-06-09
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Construction and Structure Determination of a Three-Dimensional DNA Crystal.
J.Am.Chem.Soc., 138, 2016
5KEO
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BU of 5keo by Molmil
Structure Determination of a Self-Assembling DNA Crystal
Descriptor: CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*GP*T)-3'), ...
Authors:Simmons, C.R, Birktoft, J.J, Seeman, N.C, Yan, H.
Deposit date:2016-06-09
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Construction and Structure Determination of a Three-Dimensional DNA Crystal.
J.Am.Chem.Soc., 138, 2016
5I6Q
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BU of 5i6q by Molmil
Crystal structure of color device state B
Descriptor: DNA (26-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*GP*TP*GP*GP*TP*AP*TP*C)-3'), DNA (5'-D(*CP*AP*GP*AP*TP*AP*CP*CP*TP*GP*AP*TP*CP*GP*GP*AP*CP*TP*AP*CP*G)-3'), ...
Authors:Hao, Y, Birktoft, J, Seeman, N.C.
Deposit date:2016-02-16
Release date:2017-01-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.912 Å)
Cite:A device that operates within a self-assembled 3D DNA crystal.
Nat Chem, 9, 2017
5I6T
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BU of 5i6t by Molmil
Crystal structure of color device state C
Descriptor: DNA (26-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*GP*TP*GP*GP*TP*AP*TP*C)-3'), DNA (5'-D(*CP*AP*GP*AP*TP*AP*CP*CP*TP*GP*AP*TP*CP*GP*GP*AP*CP*TP*AP*CP*G)-3'), ...
Authors:Hao, Y, Birktoft, J, Seeman, N.C.
Deposit date:2016-02-16
Release date:2017-01-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (5.283 Å)
Cite:A device that operates within a self-assembled 3D DNA crystal.
Nat Chem, 9, 2017
9GGC
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BU of 9ggc by Molmil
Structure of the G848S mutant of human mitochondrial DNA polymerase gamma
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 642, 2025
9GGB
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BU of 9ggb by Molmil
Structure of the G848S mutant of human mitochondrial DNA polymerase gamma in complex with PZL-A
Descriptor: 1-[(4S)-8-chloranyl-3,4-dihydro-2H-chromen-4-yl]-3-(1-phenylpyrazol-3-yl)urea, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 642, 2025
9GGF
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BU of 9ggf by Molmil
Structure of WT human mitochondrial DNA polymerase gamma
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 642, 2025
9GGE
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BU of 9gge by Molmil
Structure of the A467T mutant of human mitochondrial DNA polymerase gamma
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 642, 2025
9GGD
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BU of 9ggd by Molmil
Structure of the A467T mutant of human mitochondrial DNA polymerase gamma in complex with PZL-A
Descriptor: 1-[(4S)-8-chloranyl-3,4-dihydro-2H-chromen-4-yl]-3-(1-phenylpyrazol-3-yl)urea, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 642, 2025
7KRN
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BU of 7krn by Molmil
Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2020-11-20
Release date:2021-04-21
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021

 

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