4QQB
 
 | | Structural basis for the assembly of the SXL-UNR translation regulatory complex | | Descriptor: | Protein sex-lethal, Upstream of N-ras, isoform A, ... | | Authors: | Hennig, J, Popowicz, G.M, Sattler, M. | | Deposit date: | 2014-06-27 | | Release date: | 2014-09-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for the assembly of the Sxl-Unr translation regulatory complex.
Nature, 515, 2014
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2MKL
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7P4N
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2N88
 | | Chromodomain 3 (CD3) of cpSRP43 | | Descriptor: | Signal recognition particle 43 kDa protein, chloroplastic | | Authors: | Hennig, J, Sattler, M. | | Deposit date: | 2015-10-06 | | Release date: | 2015-12-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
Nat Commun, 6, 2015
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7ZHR
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7ZHH
 | | Complex structure of drosophila Unr CSD789 and a poly(A) RNA sequence | | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION, Upstream of N-ras, ... | | Authors: | Hollmann, N.M, Jagtap, P.K.A, Hennig, J. | | Deposit date: | 2022-04-06 | | Release date: | 2022-12-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein.
Nucleic Acids Res., 51, 2023
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9EN7
 | | Hrp48 RRM1 domain | | Descriptor: | GLYCEROL, Heterogeneous nuclear ribonucleoprotein 27C | | Authors: | Lomoschitz, A, Hennig, J, Murciano, B, Meyer, J. | | Deposit date: | 2024-03-12 | | Release date: | 2024-11-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | The Drosophila RNA binding protein Hrp48 binds a specific RNA sequence of the msl-2 mRNA 3' UTR to regulate translation.
Biophys.Chem., 316, 2024
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7QFT
 | | Crystal structure of KLK6 in complex with compound 16a | | Descriptor: | KLK6 Activity-Based Probe (Ahx-DPhe-Cha-Dht-Arg-DPP), Kallikrein-6 | | Authors: | Jagtap, P.K.A, Zhang, L, De Vita, E, Tate, E.W, Hennig, J. | | Deposit date: | 2021-12-06 | | Release date: | 2022-11-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion.
J.Am.Chem.Soc., 144, 2022
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7QFV
 | | Crystal structure of KLK6 in complex with compound 17a | | Descriptor: | KLK6 Activity-Based Probe (Ahx-DPhe-Ser(Z)-Dht-Arg-DPP), Kallikrein-6 | | Authors: | Jagtap, P.K.A, Zhang, L, De Vita, E, Tate, E.W, Hennig, J. | | Deposit date: | 2021-12-06 | | Release date: | 2022-10-26 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion.
J.Am.Chem.Soc., 144, 2022
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4GZJ
 | | Active-site mutant of potato endo-1,3-beta-glucanase in complex with laminaratriose and laminaratetrose | | Descriptor: | Glucan endo-1,3-beta-D-glucosidase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | | Authors: | Wojtkowiak, A, Witek, K, Hennig, J, Jaskolski, M. | | Deposit date: | 2012-09-06 | | Release date: | 2013-01-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structures of an active-site mutant of a plant 1,3-beta-glucanase in complex with oligosaccharide products of hydrolysis
Acta Crystallogr.,Sect.D, 69, 2013
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4GZI
 | | Active-site mutant of potato endo-1,3-beta-glucanase in complex with laminaratriose | | Descriptor: | Glucan endo-1,3-beta-D-glucosidase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | | Authors: | Wojtkowiak, A, Witek, K, Hennig, J, Jaskolski, M. | | Deposit date: | 2012-09-06 | | Release date: | 2013-01-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structures of an active-site mutant of a plant 1,3-beta-glucanase in complex with oligosaccharide products of hydrolysis
Acta Crystallogr.,Sect.D, 69, 2013
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9HSA
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7QI0
 | | Crystal structure of KLK6 in complex with compound DKFZ918 | | Descriptor: | (5~{R})-3-(6-carbamimidoylpyridin-3-yl)-~{N}-[(1~{S})-1-naphthalen-1-ylpropyl]-2-oxidanylidene-1,3-oxazolidine-5-carboxamide, Kallikrein-6 | | Authors: | Jagtap, P.K.A, Baumann, A, Lohbeck, J, Isak, D, Miller, A, Hennig, J. | | Deposit date: | 2021-12-14 | | Release date: | 2022-11-23 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
Rsc Adv, 12, 2022
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7QHZ
 | | Crystal structure of KLK6 in complex with compound DKFZ917 | | Descriptor: | (5~{R})-3-(4-carbamimidoylphenyl)-~{N}-[(1~{S})-1-naphthalen-1-ylpropyl]-2-oxidanylidene-1,3-oxazolidine-5-carboxamide, GLYCEROL, Kallikrein-6 | | Authors: | Jagtap, P.K.A, Baumann, A, Lohbeck, J, Isak, D, Miller, A, Hennig, J. | | Deposit date: | 2021-12-14 | | Release date: | 2022-11-23 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
Rsc Adv, 12, 2022
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8A38
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8PJB
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8P66
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8PJJ
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8AMS
 | | Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin | | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Polyubiquitin-C, ... | | Authors: | Perez-Borrajero, C, Kotova, I, Murciano, B, Hennig, J. | | Deposit date: | 2022-08-04 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and biophysical studies of TRIM2 and TRIM3
To Be Published
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4Q9B
 | | IgNAR antibody domain C2 | | Descriptor: | Novel antigen receptor | | Authors: | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2014-04-30 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q9C
 | | IgNAR antibody domain C3 | | Descriptor: | CHLORIDE ION, Novel antigen receptor, SODIUM ION, ... | | Authors: | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2014-04-30 | | Release date: | 2014-07-02 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q97
 | | IgNAR antibody domain C1 | | Descriptor: | Novel antigen receptor | | Authors: | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2014-04-29 | | Release date: | 2014-07-02 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6FWN
 | | Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor | | Descriptor: | von Willebrand factor | | Authors: | Xu, E.-R, von Buelow, S, Chen, P.-C, Lenting, P.J, Kolsek, K, Aponte-Santamaria, C, Simon, B, Foot, J, Obser, T, Graeter, F, Schneppenheim, R, Denis, C.V, Wilmanns, M, Hennig, J. | | Deposit date: | 2018-03-06 | | Release date: | 2018-10-24 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor.
Blood, 133, 2019
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6I3R
 | | Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1/2 of Drosophila helicase MLE | | Descriptor: | Dosage compensation regulator | | Authors: | Jagtap, P.K.A, Buelow, S.v, Masiewicz, P, Simon, B, Hennig, J. | | Deposit date: | 2018-11-07 | | Release date: | 2019-02-20 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless.
Nucleic Acids Res., 47, 2019
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8AMR
 | | Coiled-coil domain of human TRIM3 | | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Tripartite motif-containing protein 3 | | Authors: | Perez-Borrajero, C, Murciano, B, Hennig, J. | | Deposit date: | 2022-08-04 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural and biophysical studies of TRIM2 and TRIM3
To Be Published
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