6QJ4
 
 | | Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex bound to the Smc4 ATPase head in complex with the C-terminal domain of Brn1 | | 分子名称: | Brn1, Condensin complex subunit 1,Condensin complex subunit 1,Condensin complex subunit 1, Condensin complex subunit 2, ... | | 著者 | Hassler, M, Haering, C.H, Kschonsak, M. | | 登録日 | 2019-01-22 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (5.8 Å) | | 主引用文献 | Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
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6QJ2
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2QDJ
 | | Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture | | 分子名称: | Retinoblastoma-associated protein | | 著者 | Hassler, M, Mittnacht, S, Pearl, L.H. | | 登録日 | 2007-06-21 | | 公開日 | 2008-01-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
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1HBX
 | | Ternary Complex of SAP-1 and SRF with specific SRE DNA | | 分子名称: | 5'-D(*CP*AP*CP*AP*CP*CP*GP*GP*AP*AP*GP*TP*CP* CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*CP*AP*T)-3', 5'-D(*GP*AP*TP*GP*GP*CP*CP*TP*AP*AP*TP*TP*AP* GP*GP*AP*CP*TP*TP*CP*CP*GP*GP*TP*G)-3', ETS-DOMAIN PROTEIN ELK-4, ... | | 著者 | Hassler, M, Richmond, T.J. | | 登録日 | 2001-04-20 | | 公開日 | 2001-06-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The B-Box Dominates Sap-1/Srf Interactions in the Structure of the Ternary Complex
Embo J., 20, 2001
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6QJ3
 | | Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex | | 分子名称: | Brn1, Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2 | | 著者 | Hassler, M, Haering, C.H, Kschonsak, M. | | 登録日 | 2019-01-22 | | 公開日 | 2019-07-03 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
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6QJ0
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6QJ1
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3TE6
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6Q6E
 | | Structural and functional insights into the condensin ATPase cycle | | 分子名称: | Condensin complex subunit 2,Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein | | 著者 | Simon, B, Hassler, M, Haering, C.H, Hennig, J. | | 登録日 | 2018-12-10 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
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4AV1
 | | Crystal structure of the human PARP-1 DNA binding domain in complex with DNA | | 分子名称: | 5'-D(*AP*AP*GP*TP*GP*TP*TP*GP*CP*AP*TP*TP)-3', 5'-D(*TP*AP*AP*TP*GP*CP*AP*AP*CP*AP*CP*TP)-3', POLY [ADP-RIBOSE] POLYMERASE 1, ... | | 著者 | Ali, A.A.E, Timinszky, G, Arribas-Bosacoma, R, Kozlowski, M, Hassa, P.O, Hassler, M, Ladurner, A.G, Pearl, L.H, Oliver, A.W. | | 登録日 | 2012-05-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2012-07-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The Zinc-Finger Domains of Parp1 Cooperate to Recognise DNA Strand-Breaks
Nat.Struct.Mol.Biol., 19, 2012
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7QFW
 | | S.c. Condensin peripheral Ycg1 subcomplex bound to DNA | | 分子名称: | Condensin complex subunit 2, Condensin complex subunit 3, Synthetic DNA ligand, ... | | 著者 | Lecomte, L, Hassler, M, Haering, C, Eustermann, S. | | 登録日 | 2021-12-06 | | 公開日 | 2022-06-15 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
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7QEN
 | | S.c. Condensin core in DNA- and ATP-bound state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Condensin complex subunit 1, Condensin complex subunit 2, ... | | 著者 | Lecomte, L, Hassler, M, Haering, C, Eustermann, S. | | 登録日 | 2021-12-03 | | 公開日 | 2022-06-15 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
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6YVV
 | | Condensin complex from S.cerevisiae ATP-free apo bridged state | | 分子名称: | Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2, ... | | 著者 | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Haering, C.H, Aragon, L, Lowe, J. | | 登録日 | 2020-04-28 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-08-19 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
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6YVD
 | | Head segment of the S.cerevisiae condensin holocomplex in presence of ATP | | 分子名称: | Condensin complex subunit 2, Condensin complex subunit 3, Structural maintenance of chromosomes protein 2, ... | | 著者 | Merkel, F, Haering, C.H, Hassler, M, Lee, B.G, Lowe, J. | | 登録日 | 2020-04-28 | | 公開日 | 2020-07-22 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
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6YVU
 | | Condensin complex from S.cerevisiae ATP-free apo non-engaged state | | 分子名称: | Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2,Smc2, ... | | 著者 | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Aragon, L, Haering, C.H, Lowe, J. | | 登録日 | 2020-04-28 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-08-19 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
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4KHA
 | | Structural basis of histone H2A-H2B recognition by the essential chaperone FACT | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Histone H2A, ... | | 著者 | Hondele, M, Halbach, F, Hassler, M, Ladurner, A.G. | | 登録日 | 2013-04-30 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.
Nature, 499, 2013
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4IQY
 | | Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2 | | 分子名称: | MAGNESIUM ION, O-acetyl-ADP-ribose deacetylase MACROD2, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | 著者 | Jankevicius, G, Hassler, M, Golia, B, Rybin, V, Zacharias, M, Timinszky, G, Ladurner, A.G. | | 登録日 | 2013-01-14 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A family of macrodomain proteins reverses cellular mono-ADP-ribosylation.
Nat.Struct.Mol.Biol., 20, 2013
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3ZCO
 | | Crystal structure of S. cerevisiae Sir3 C-terminal domain | | 分子名称: | REGULATORY PROTEIN SIR3 | | 著者 | Oppikofer, M, Kueng, S, Keusch, J.J, Hassler, M, Ladurner, A.G, Gut, H, Gasser, S.M. | | 登録日 | 2012-11-21 | | 公開日 | 2013-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Dimerization of Sir3 Via its C-Terminal Winged Helix Domain is Essential for Yeast Heterochromatin Formation.
Embo J., 32, 2013
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2V7E
 | | Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), unliganded | | 分子名称: | HISTONE-ARGININE METHYLTRANSFERASE CARM1, MERCURY (II) ION | | 著者 | Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H. | | 登録日 | 2007-07-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
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2V74
 | | Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine | | 分子名称: | HISTONE-ARGININE METHYLTRANSFERASE CARM1, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H. | | 登録日 | 2007-07-26 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
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5OQO
 | | Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (crystal form II) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Condensin complex subunit 2, Condensin complex subunit 3, ... | | 著者 | Kschonsak, M, Hassler, M, Haering, C.H. | | 登録日 | 2017-08-14 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017
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5OQN
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5OQQ
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5OQR
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5OQP
 | | Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (crystal form I) | | 分子名称: | Condensin complex subunit 2, Condensin complex subunit 3, DNA (5'-D(*GP*AP*TP*GP*TP*GP*TP*AP*GP*CP*TP*AP*CP*AP*CP*AP*TP*C)-3'), ... | | 著者 | Kschonsak, M, Hassler, M, Haering, C.H. | | 登録日 | 2017-08-14 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017
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