3TE6
Crystal Structure of the S. cerevisiae Sir3 AAA+ domain
Summary for 3TE6
| Entry DOI | 10.2210/pdb3te6/pdb |
| Related | 1NYH 2FL7 2FVU 3OWT |
| Descriptor | Regulatory protein SIR3 (2 entities in total) |
| Functional Keywords | heterochromatin, gene silencing, sir complex, hmr, hml, telomere, aaa+ domain, structural, sir4, sir3, sir2, nucleus, gene regulation |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) |
| Cellular location | Nucleus: P06701 |
| Total number of polymer chains | 2 |
| Total formula weight | 73510.89 |
| Authors | Hassler, M.,Ladurner, A.G. (deposition date: 2011-08-12, release date: 2011-08-31, Last modification date: 2011-09-14) |
| Primary citation | Ehrentraut, S.,Hassler, M.,Oppikofer, M.,Kueng, S.,Weber, J.M.,Mueller, J.W.,Gasser, S.M.,Ladurner, A.G.,Ehrenhofer-Murray, A.E. Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79. Genes Dev., 25:1835-1846, 2011 Cited by PubMed: 21896656DOI: 10.1101/gad.17175111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8001 Å) |
Structure validation
Download full validation report
