2M74
| 1H, 13C and 15N assignments of the four N-terminal domains of human fibrillin-1 | 分子名称: | Fibrillin-1 | 著者 | Yadin, D.A, Robertson, I.B, Jensen, S.A, Handford, P.A, Redfield, C. | 登録日 | 2013-04-17 | 公開日 | 2013-09-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly. Structure, 21, 2013
|
|
1APJ
| NMR STUDY OF THE TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN-LIKE DOMAIN (TB MODULE/8-CYS DOMAIN), NMR, 21 STRUCTURES | 分子名称: | FIBRILLIN | 著者 | Yuan, X, Downing, A.K, Knott, V, Handford, P.A. | 登録日 | 1997-07-22 | 公開日 | 1998-01-28 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils. EMBO J., 16, 1997
|
|
2BOX
| EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium. | 分子名称: | CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ... | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | 登録日 | 2005-04-14 | 公開日 | 2006-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55. J.Biol.Chem., 282, 2007
|
|
2BOU
| EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium. | 分子名称: | BARIUM ION, CACODYLATE ION, CALCIUM ION, ... | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | 登録日 | 2005-04-14 | 公開日 | 2006-10-18 | 最終更新日 | 2017-01-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55. J.Biol.Chem., 282, 2007
|
|
2BO2
| EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium. | 分子名称: | CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | 登録日 | 2005-04-07 | 公開日 | 2006-08-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55. J.Biol.Chem., 282, 2007
|
|
1TOZ
| NMR structure of the human NOTCH-1 ligand binding region | 分子名称: | Neurogenic locus notch homolog protein 1 | 著者 | Hambleton, S, Valeyev, N.Y, Muranyi, A, Knott, V, Werner, J.M, Mcmichael, A.J, Handford, P.A, Downing, A.K. | 登録日 | 2004-06-15 | 公開日 | 2004-10-12 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional properties of the human notch-1 ligand binding region STRUCTURE, 12, 2004
|
|
5MS9
| |
2VJ2
| Human Jagged-1, domains DSL and EGFs1-3 | 分子名称: | D-MALATE, JAGGED-1 | 著者 | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Handford, P.A, Lea, S.M. | 登録日 | 2007-12-06 | 公開日 | 2008-07-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition. Nat.Struct.Mol.Biol., 15, 2008
|
|
2W86
| Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form | 分子名称: | CALCIUM ION, FIBRILLIN-1, IODIDE ION | 著者 | Jensen, S.A, Iqbal, S, Lowe, E.D, Redfield, C, Handford, P.A. | 登録日 | 2009-01-09 | 公開日 | 2009-05-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins. Structure, 17, 2009
|
|
5FMA
| human Notch 1, EGF 4-7 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C. | 登録日 | 2015-11-02 | 公開日 | 2016-04-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies. Structure, 24, 2016
|
|
5FM9
| human Notch 1, EGF 4-7 | 分子名称: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C. | 登録日 | 2015-11-02 | 公開日 | 2016-04-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies. Structure, 24, 2016
|
|
1EMN
| NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE | 分子名称: | CALCIUM ION, FIBRILLIN | 著者 | Downing, A.K, Campbell, I.D, Handford, P.A. | 登録日 | 1996-08-05 | 公開日 | 1996-12-23 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders. Cell(Cambridge,Mass.), 85, 1996
|
|
1EMO
| NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES | 分子名称: | CALCIUM ION, FIBRILLIN | 著者 | Downing, A.K, Campbell, I.D, Handford, P.A. | 登録日 | 1996-08-05 | 公開日 | 1996-12-23 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders. Cell(Cambridge,Mass.), 85, 1996
|
|
1UZK
| Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Ca bound to cbEGF23 domain only | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-13 | 公開日 | 2006-05-24 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
|
|
1UZP
| Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Sm bound form cbEGF23 domain only. | 分子名称: | FIBRILLIN-1, SAMARIUM (III) ION | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-15 | 公開日 | 2004-04-08 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
|
|
1UZJ
| Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form. | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-12 | 公開日 | 2004-04-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
|
|
1UZQ
| Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23 domain only. | 分子名称: | FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-15 | 公開日 | 2004-04-08 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
|
|
5MVX
| Human DLL4 C2-EGF3 | 分子名称: | Delta-like protein 4, alpha-L-fucopyranose | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-17 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
|
|
5MW7
| Human Jagged2 C2-EGF3 | 分子名称: | Protein jagged-2, alpha-L-fucopyranose | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
|
|
5MWB
| Human Notch-2 EGF11-13 | 分子名称: | CALCIUM ION, Neurogenic locus notch homolog protein 2, alpha-L-fucopyranose, ... | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
|
|
5MWF
| Human Jagged2 C2-EGF2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
|
|
5MW5
| Human Jagged2 C2-EGF2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protein jagged-2 | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
|
|
1HJ7
| NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures | 分子名称: | CALCIUM ION, LDL RECEPTOR | 著者 | Saha, S, Handford, P.A, Campbell, I.D, Downing, A.K. | 登録日 | 2001-01-09 | 公開日 | 2001-07-11 | 最終更新日 | 2018-02-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Ldl Receptor Egf-Ab Pair: A Paradigm for the Assembly of Tandem Calcium Binding Egf Domains Structure, 9, 2001
|
|
1KSQ
| NMR Study of the Third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1 | 分子名称: | LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 1 | 著者 | Lack, J, O'leary, J.M, Knott, V, Yuan, X, Rifkin, D.B, Handford, P.A, Downing, A.K. | 登録日 | 2002-01-14 | 公開日 | 2003-08-26 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly
of the Large Latent Complex that Sequesters Latent TGF-beta. J.Mol.Biol., 334, 2003
|
|
1LMJ
| NMR Study of the Fibrillin-1 cbEGF12-13 Pair of Ca2+ Binding Epidermal Growth Factor-like Domains | 分子名称: | CALCIUM ION, fibrillin 1 | 著者 | Smallridge, R.S, Whiteman, P, Werner, J.M, Campbell, I.D, Handford, P.A, Downing, A.K. | 登録日 | 2002-05-02 | 公開日 | 2003-04-29 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure and Dynamics of a Calcium Binding Epidermal Growth
Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1. J.Biol.Chem., 278, 2003
|
|