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1HRI
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BU of 1hri by Molmil
STRUCTURE DETERMINATION OF ANTIVIRAL COMPOUND SCH 38057 COMPLEXED WITH HUMAN RHINOVIRUS 14
Descriptor: 1-[6-(2-CHLORO-4-METHYXYPHENOXY)-HEXYL]-IMIDAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
Authors:Zhang, A, Nanni, R.G, Oren, D.A, Arnold, E.
Deposit date:1992-10-01
Release date:1993-10-31
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure determination of antiviral compound SCH 38057 complexed with human rhinovirus 14.
J.Mol.Biol., 230, 1993
1I9S
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BU of 1i9s by Molmil
CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1I9T
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BU of 1i9t by Molmil
CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1I7D
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BU of 1i7d by Molmil
NONCOVALENT COMPLEX OF E.COLI DNA TOPOISOMERASE III WITH AN 8-BASE SINGLE-STRANDED DNA OLIGONUCLEOTIDE
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', CHLORIDE ION, DNA TOPOISOMERASE III, ...
Authors:Changela, A, DiGate, R.J, Mondragon, A.
Deposit date:2001-03-08
Release date:2001-06-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule.
Nature, 411, 2001
1IAZ
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BU of 1iaz by Molmil
EQUINATOXIN II
Descriptor: EQUINATOXIN II, SULFATE ION
Authors:Athanasiadis, A, Anderluh, G, Macek, P, Turk, D.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina.
Structure, 9, 2001
6E6L
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BU of 6e6l by Molmil
Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F:Y60A mutant of human cellular retinol binding protein II
Descriptor: ACETATE ION, RETINAL, Retinol-binding protein 2
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-07-25
Release date:2019-10-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141, 2019
9C88
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BU of 9c88 by Molmil
Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Translocating a Portion of a Branched-Degron DHFR Substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-06-12
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Cryo-EM structure of a fully-engaged DHFR-ssrA substrate and the AAA+ ClpXP protease
To Be Published
9C87
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BU of 9c87 by Molmil
Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Linear-Degron DHFR-ssrA Substrate Bound with MTX
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-06-12
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Linear-Degron DHFR-ssrA Substrate Bound with MTX
To Be Published
9CZ1
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BU of 9cz1 by Molmil
Cryo-EM structure of a 'hat' portion of FtsH.HflK.HflC complex
Descriptor: Modulator of FtsH protease HflC, Modulator of FtsH protease HflK
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-08-03
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of a 'hat' portion of FtsH.HflK.HflC complex
To Be Published
9CZ2
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BU of 9cz2 by Molmil
Cryo-EM structure of a nautilus-like HflK/C assembly in complex with FtsH AAA protease
Descriptor: ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Modulator of FtsH protease HflK
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-08-03
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure of a nautilus-like HflK/C assembly in complex with FtsH AAA protease
To Be Published
1N6J
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BU of 1n6j by Molmil
Structural basis of sequence-specific recruitment of histone deacetylases by Myocyte Enhancer Factor-2
Descriptor: 5'-D(*AP*GP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*CP*T)-3', Calcineurin-binding protein Cabin 1, ...
Authors:Han, A, Pan, F, Stroud, J.C, Youn, H.D, Liu, J.O, Chen, L.
Deposit date:2002-11-11
Release date:2003-11-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2
Nature, 422, 2003
3PIQ
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BU of 3piq by Molmil
Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1
Descriptor: Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain
Authors:Changela, A, Gorny, M.K, Zolla-Pazner, S, Kwong, P.D.
Deposit date:2010-11-07
Release date:2011-01-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.325 Å)
Cite:Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1.
J.Virol., 85, 2011
5ALC
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BU of 5alc by Molmil
Ticagrelor antidote candidate Fab 72 in complex with ticagrelor
Descriptor: ANTI-TICAGRELOR FAB 72, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S.
Deposit date:2015-03-07
Release date:2015-04-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Functional Characterisation of a Specific Antidote for Ticagrelor.
Blood, 125, 2015
5ALB
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BU of 5alb by Molmil
Ticagrelor antidote candidate MEDI2452 in complex with ticagrelor
Descriptor: MEDI2452 HEAVY CHAIN, MEDI2452 LIGHT CHAIN, Ticagrelor
Authors:Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S.
Deposit date:2015-03-07
Release date:2015-04-01
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural and Functional Characterisation of a Specific Antidote for Ticagrelor.
Blood, 125, 2015
8U9L
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BU of 8u9l by Molmil
Crystal Structure of RelA-cRel chimera complex with DNA
Descriptor: DNA (5'-D(P*GP*AP*AP*TP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*TP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*AP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*AP*TP*TP*C)-3'), Transcription factor p65,Proto-oncogene c-Rel chimera
Authors:Chang, A, Wu, Y, Li, S.X, Smale, S, Chen, L.
Deposit date:2023-09-19
Release date:2024-10-02
Method:X-RAY DIFFRACTION (3.091 Å)
Cite:Crystal Structure of RelA-cRel chimera complex with DNA
To Be Published
8S1X
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BU of 8s1x by Molmil
Crystal structure of Actinonin-bound PDF1 and the computationally designed DBAct553_1 protein binder
Descriptor: ACTINONIN, DBAct553_1, FORMIC ACID, ...
Authors:Marchand, A, Pacesa, M, Correia, B.E.
Deposit date:2024-02-16
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Targeting hybrid neosurface fingerprints for the design of de novo drug-induced protein interactions
To Be Published
7N40
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BU of 7n40 by Molmil
Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex
Descriptor: Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog
Authors:Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M.
Deposit date:2021-06-02
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Nat Commun, 13, 2022
6ON7
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BU of 6on7 by Molmil
Crystal Structure of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C Mutant of Human Cellular Retinol Binding Protein II
Descriptor: Retinol-binding protein 2
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2019-04-20
Release date:2019-10-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.981 Å)
Cite:Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141, 2019
6WP0
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BU of 6wp0 by Molmil
The Crystal Structure of Domain-Swapped Trimer Q108K:T51D variant of HCRBPII
Descriptor: ACETATE ION, GLYCEROL, Retinol-binding protein 2
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2020-04-26
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering.
Chembiochem, 21, 2020
1XMK
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BU of 1xmk by Molmil
The Crystal structure of the Zb domain from the RNA editing enzyme ADAR1
Descriptor: CADMIUM ION, CHLORIDE ION, Double-stranded RNA-specific adenosine deaminase, ...
Authors:Athanasiadis, A, Placido, D, Maas, S, Brown II, B.A, Lowenhaupt, K, Rich, A.
Deposit date:2004-10-03
Release date:2005-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:The Crystal Structure of the Z[beta] Domain of the RNA-editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-domains.
J.Mol.Biol., 351, 2005
1YN9
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BU of 1yn9 by Molmil
Crystal structure of baculovirus RNA 5'-phosphatase complexed with phosphate
Descriptor: PHOSPHATE ION, polynucleotide 5'-phosphatase
Authors:Changela, A, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2005-01-24
Release date:2005-02-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of baculovirus RNA triphosphatase complexed with phosphate
J.Biol.Chem., 280, 2005
6MCV
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BU of 6mcv by Molmil
Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II
Descriptor: RETINAL, Retinol-binding protein 2
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-09-02
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141, 2019
6MQJ
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BU of 6mqj by Molmil
Crystal Structure of the All-Trans Retinal bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121Q mutant of Human Cellular Retinoic Acid Binding Protein II Irradiated with 532 nm Laser for 10 minutes at 2.1 Angstrom Resolution
Descriptor: Cellular retinoic acid-binding protein 2, RETINAL
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-10-09
Release date:2019-01-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.125 Å)
Cite:Mimicking Microbial Rhodopsin Isomerization in a Single Crystal.
J. Am. Chem. Soc., 141, 2019
6MOQ
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BU of 6moq by Molmil
Crystal Structure of the All-trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121W Mutant of Human Cellular Retinoic Acid Binding Protein II in the Dark at 2.2 Angstrom Resolution
Descriptor: Cellular retinoic acid-binding protein 2, RETINAL
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-10-04
Release date:2019-01-09
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Mimicking Microbial Rhodopsin Isomerization in a Single Crystal.
J. Am. Chem. Soc., 141, 2019
3LST
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BU of 3lst by Molmil
Crystal Structure of CalO1, Methyltransferase in Calicheamicin Biosynthesis, SAH bound form
Descriptor: 1,2-ETHANEDIOL, CalO1 Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-02-12
Release date:2010-03-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 67, 2011

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