6ON5

Crystal Structure of the Zn-bound Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II

Summary for 6ON5

DescriptorRetinol-binding protein 2, ZINC ION (3 entities in total)
Functional Keywordsretinol, ilbp, protein switch, cytosolic protein, lipid binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight31316.43
Authors
Ghanbarpour, A.,Geiger, J. (deposition date: 2019-04-20, release date: 2019-10-16, Last modification date: 2019-12-18)
Primary citation
Ghanbarpour, A.,Pinger, C.,Esmatpour Salmani, R.,Assar, Z.,Santos, E.M.,Nosrati, M.,Pawlowski, K.,Spence, D.,Vasileiou, C.,Jin, X.,Borhan, B.,Geiger, J.H.
Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141:17125-17132, 2019
PubMed: 31557439 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.9b04664
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.638 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25560 1.7% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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