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4V62
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BU of 4v62 by Molmil
Crystal Structure of cyanobacterial Photosystem II
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Guskov, A, Gabdulkhakov, A, Kern, J, Broser, M, Zouni, A, Saenger, W.
Deposit date:2008-01-17
Release date:2014-07-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Cyanobacterial photosystem II at 2.9-A resolution and the role of quinones, lipids, channels and chloride
Nat.Struct.Mol.Biol., 16, 2009
4EGW
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BU of 4egw by Molmil
The structure of the soluble domain of CorA from Methanocaldococcus jannaschii
Descriptor: 1,4-BUTANEDIOL, HEXANE-1,6-DIOL, MAGNESIUM ION, ...
Authors:Guskov, A, Nordin, N, Reynaud, A, Engman, H, Lundback, A.-K, Jong, A.J.O, Cornvik, T, Phua, T, Eshaghi, S.
Deposit date:2012-04-02
Release date:2012-10-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA
Proc.Natl.Acad.Sci.USA, 109, 2012
4EV6
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BU of 4ev6 by Molmil
The complete structure of CorA magnesium transporter from Methanocaldococcus jannaschii
Descriptor: MAGNESIUM ION, Magnesium transport protein CorA, UNDECYL-MALTOSIDE
Authors:Guskov, A, Nordin, N, Reynaud, A, Engman, H, Lundback, A.-K, Jong, A.J.O, Cornvik, T, Phua, T, Eshaghi, S.
Deposit date:2012-04-25
Release date:2012-10-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA
Proc.Natl.Acad.Sci.USA, 109, 2012
5DWY
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BU of 5dwy by Molmil
Crystal structure of a substrate-free glutamate transporter homologue GltTk
Descriptor: DI(HYDROXYETHYL)ETHER, Proton/glutamate symporter, SDF family, ...
Authors:Guskov, A, Slotboom, D.J.
Deposit date:2015-09-23
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.
Nat Commun, 7, 2016
5E9S
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BU of 5e9s by Molmil
Crystal structure of substrate-bound glutamate transporter homologue GltTk
Descriptor: ASPARTIC ACID, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Guskov, A, Slotboom, D.J.
Deposit date:2015-10-15
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.
Nat Commun, 7, 2016
4QTN
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BU of 4qtn by Molmil
Crystal structure of the Vitamin B3 transporter PnuC
Descriptor: Nicotinamide riboside, Nicotinamide riboside transporter PnuC, octyl beta-D-glucopyranoside
Authors:Guskov, A, Jaehme, M, Slotboom, D.J.
Deposit date:2014-07-08
Release date:2014-10-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the Vitamin B3 transporter PnuC
Nat.Struct.Mol.Biol., 2014
5D3M
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BU of 5d3m by Molmil
Folate ECF transporter: AMPPNP bound state
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Guskov, A, Swier, L.J.Y.M, Slotboom, D.J.
Deposit date:2015-08-06
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.303 Å)
Cite:Structural insight in the toppling mechanism of an energy-coupling factor transporter.
Nat Commun, 7, 2016
6FXG
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BU of 6fxg by Molmil
Crystal structure of substrate binding domain 1 (SBD1) OF ABC transporter GLNPQ in complex with Asparagine
Descriptor: ASPARAGINE, Amino acid ABC transporter membrane protein PAAT family
Authors:Guskov, A, Schuurman-Wolters, G.K, Poolman, B.
Deposit date:2018-03-09
Release date:2019-03-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of substrate binding domain 1 (SBD1) OF ABC transporter GLNPQ in complex with Asparagine
To Be Published
4KY0
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BU of 4ky0 by Molmil
Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis
Descriptor: Proton/glutamate symporter, SDF family, TETRAETHYLENE GLYCOL
Authors:Guskov, A, Jensen, S, Rempel, S, Hanelt, I, Slotboom, D.J.
Deposit date:2013-05-28
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a substrate-free aspartate transporter.
Nat.Struct.Mol.Biol., 20, 2013
4LA9
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BU of 4la9 by Molmil
Crystal structure of an empty substrate binding domain 1 (SBD1) OF ABC TRANSPORTER GLNPQ from lactococcus lactis
Descriptor: DI(HYDROXYETHYL)ETHER, Glutamine ABC transporter permease and substrate binding protein protein, PHOSPHATE ION
Authors:Guskov, A, Schuurman-Wolters, G.K, Slotboom, D.J, Poolman, B.
Deposit date:2013-06-19
Release date:2013-09-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria.
Structure, 21, 2013
3KZI
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BU of 3kzi by Molmil
Crystal Structure of Monomeric Form of Cyanobacterial Photosystem II
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Gabdulkhakov, A, Guskov, A, Broser, M, Kern, J, Zouni, A, Saenger, W.
Deposit date:2009-12-08
Release date:2010-06-16
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal Structure of Monomeric Photosystem II from Thermosynechococcus elongatus at 3.6-A Resolution
J.Biol.Chem., 285, 2010
7P4I
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BU of 7p4i by Molmil
Structure of human ASCT1 transporter
Descriptor: Neutral amino acid transporter A
Authors:Stetsenko, A, Stehantsev, P, Gati, C, Guskov, A.
Deposit date:2021-07-11
Release date:2021-10-06
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:A structural view onto disease-linked mutations in the human neutral amino acid exchanger ASCT1
Comput Struct Biotechnol J, 19, 2021
4V82
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BU of 4v82 by Molmil
Crystal structure of cyanobacterial Photosystem II in complex with terbutryn
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Gabdulkhakov, A, Broser, M, Guskov, A, Kern, J, Glockner, C, Muh, F, Saenger, W, Zouni, A.
Deposit date:2010-11-30
Release date:2014-07-09
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of cyanobacterial photosystem II Inhibition by the herbicide terbutryn
J.Biol.Chem., 286, 2011
8AFA
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BU of 8afa by Molmil
Cryo-EM structure of a substrate-bound glutamate transporter homologue GltTk encapsulated within a nanodisc
Descriptor: ASPARTIC ACID, Proton/glutamate symporter, SDF family
Authors:Whittaker, J.J, Guskov, A.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Mutation in glutamate transporter homologue GltTk provides insights into pathologic mechanism of episodic ataxia 6.
Nat Commun, 14, 2023
4G4P
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BU of 4g4p by Molmil
Crystal structure of glutamine-binding protein from Enterococcus faecalis at 1.5 A
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Amino acid ABC transporter, amino acid-binding/permease protein, ...
Authors:Fulyani, F, Guskov, A, Zagar, A.V, Slotboom, D.-J, Poolman, B.
Deposit date:2012-07-16
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria.
Structure, 21, 2013
6FNP
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BU of 6fnp by Molmil
Crystal structure of ECF-CbrT, a cobalamin transporter
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Santos, J.A, Rempel, S, Guskov, A, Slotboom, D.J.
Deposit date:2018-02-05
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Functional and structural characterization of an ECF-type ABC transporter for vitamin B12.
Elife, 7, 2018
7QZ1
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BU of 7qz1 by Molmil
Formate dehydrogenase from Starkeya novella
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Formate dehydrogenase, ...
Authors:Pontillo, N, Slotboom, D.J, Guskov, A.
Deposit date:2022-01-30
Release date:2023-02-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural insight into the chemical resistance and cofactor specificity of the formate dehydrogenase from Starkeya novella.
Febs J., 290, 2023
9G6J
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BU of 9g6j by Molmil
The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) with strong density for the P-site tRNA
Descriptor: (11R,12S)- Mefloquine, 18S rRNA, 25S rRNA, ...
Authors:Kolosova, O, Zgadzay, Y, Jenner, L.B, Guskov, A, Yusupov, M.
Deposit date:2024-07-18
Release date:2025-04-23
Last modified:2025-05-07
Method:ELECTRON MICROSCOPY (2.15 Å)
Cite:Mechanism of read-through enhancement by aminoglycosides and mefloquine.
Proc.Natl.Acad.Sci.USA, 122, 2025
9G30
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BU of 9g30 by Molmil
The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) shows strong density for the A site tRNA
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Kolosova, O, Zgadzay, Y, Jenner, L.B, Guskov, A, Yusupov, M.
Deposit date:2024-07-11
Release date:2025-04-23
Last modified:2025-05-07
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Mechanism of read-through enhancement by aminoglycosides and mefloquine.
Proc.Natl.Acad.Sci.USA, 122, 2025
8P3C
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BU of 8p3c by Molmil
Full length structure of BpMIP with bound inhibitor NJS227.
Descriptor: (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A.
Deposit date:2023-05-17
Release date:2024-06-12
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors.
J.Med.Chem., 68, 2025
8P3D
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BU of 8p3d by Molmil
Full length structure of TcMIP with bound inhibitor NJS224.
Descriptor: (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-4-methyl-1-oxidanylidene-1-(pyridin-3-ylmethylamino)pentan-2-yl]piperidine-2-carboxamide, SODIUM ION, peptidylprolyl isomerase
Authors:Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A.
Deposit date:2023-05-17
Release date:2024-06-12
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors.
J.Med.Chem., 68, 2025
8P42
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BU of 8p42 by Molmil
Full length structure of TcMIP with bound inhibitor NJS227.
Descriptor: (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, DI(HYDROXYETHYL)ETHER, Macrophage infectivity potentiator
Authors:Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A.
Deposit date:2023-05-19
Release date:2024-06-12
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors.
J.Med.Chem., 68, 2025
2XZ5
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BU of 2xz5 by Molmil
MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, ...
Authors:Brams, M, Gay, E.A, Colon Saez, J, Guskov, A, van Elk, R, van der Schors, R.C, Peigneur, S, Tytgat, J, Strelkov, S.V, Smit, A.B, Yakel, J.L, Ulens, C.
Deposit date:2010-11-23
Release date:2010-12-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein
J.Biol.Chem., 286, 2011
8Q5I
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BU of 8q5i by Molmil
Structure of Candida albicans 80S ribosome in complex with cephaeline
Descriptor: 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M.
Deposit date:2023-08-09
Release date:2023-09-13
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Biopolym Cell, 2023
2XZ6
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BU of 2xz6 by Molmil
MTSET-modified Y53C mutant of Aplysia AChBP
Descriptor: 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, SOLUBLE ACETYLCHOLINE RECEPTOR
Authors:Brams, M, Gay, E.A, Colon Saez, J, Guskov, A, Van Elk, R, Van Der Schors, R.C, Peigneur, S, Tytgat, J, Strelkov, S.V, Smit, A.B, Yakel, J.L, Ulens, C.
Deposit date:2010-11-23
Release date:2010-12-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.137 Å)
Cite:Crystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein
J.Biol.Chem., 286, 2011

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