6J72
 
 | | Crystal structure of IniA from Mycobacterium smegmatis with GTP bound | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ... | | Authors: | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | | Deposit date: | 2019-01-16 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
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6J73
 | | Crystal structure of IniA from Mycobacterium smegmatis | | Descriptor: | Isoniazid inducible gene protein IniA | | Authors: | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | | Deposit date: | 2019-01-16 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.211 Å) | | Cite: | Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
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5JJ6
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8WIU
 | | Bromodomain and Extra-terminal Domain (BET) BRD4 | | Descriptor: | 7-[5-[1-(cyclopropylmethyl)-3,5-dimethyl-pyrazol-4-yl]pyridin-3-yl]-1~{H}-imidazo[4,5-b]pyridine, Isoform C of Bromodomain-containing protein 4 | | Authors: | Cao, D, Zhiyan, D, Xiong, B. | | Deposit date: | 2023-09-25 | | Release date: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis.
Eur.J.Med.Chem., 265, 2023
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8D9X
 | | Cryo-EM structure of human DELE1 in oligomeric form | | Descriptor: | Maltodextrin-binding protein,DAP3-binding cell death enhancer 1 short form | | Authors: | Yang, J, Lander, G.C. | | Deposit date: | 2022-06-11 | | Release date: | 2023-06-14 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | DELE1 oligomerization promotes integrated stress response activation.
Nat.Struct.Mol.Biol., 30, 2023
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8EFN
 | | Structure of Sp-STING3 from Stylophora pistillata coral in complex with 3',3'-cGAMP | | Descriptor: | 1,2-ETHANEDIOL, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | | Authors: | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
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8EFM
 | | Structure of coral STING receptor from Stylophora pistillata in complex with 2',3'-cGAMP | | Descriptor: | SULFATE ION, Stimulator of interferon genes protein, cGAMP | | Authors: | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-05 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
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4QQ6
 | | Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule | | Descriptor: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION | | Authors: | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-06-26 | | Release date: | 2014-08-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
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4QQD
 | | Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule | | Descriptor: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, E3 ubiquitin-protein ligase UHRF1, UNKNOWN ATOM OR ION | | Authors: | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-06-27 | | Release date: | 2014-08-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
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4Q94
 | | human RPRD1B CID in complex with a RPB1-CTD derived Ser2 phosphorylated peptide | | Descriptor: | Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, UNKNOWN ATOM OR ION, ... | | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-04-29 | | Release date: | 2014-06-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
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4ZBW
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6K2U
 | | Crystal structure of Thr66 ADP-ribosylated ubiquitin | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, MAGNESIUM ION, Polyubiquitin-C, ... | | Authors: | Wang, X, Zhou, Y, Zhu, Y. | | Deposit date: | 2019-05-15 | | Release date: | 2020-03-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.554 Å) | | Cite: | Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination.
Mol.Cell, 78, 2020
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5GNU
 | | the structure of mini-MFN1 apo | | Descriptor: | Mitofusin-1 | | Authors: | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J. | | Deposit date: | 2016-07-25 | | Release date: | 2016-11-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (4.113 Å) | | Cite: | BDLP-like folding of Mitofusin 1
To Be Published
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6IH5
 | | Crystal structure of Phosphite Dehydrogenase mutant I151R/P176E from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide | | Descriptor: | Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | Authors: | Song, X, Feng, Y, Liu, Y, Zhao, Z. | | Deposit date: | 2018-09-28 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.468 Å) | | Cite: | Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
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6IH4
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6IH2
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6IH3
 | | Crystal structure of Phosphite Dehydrogenase from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide | | Descriptor: | Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | Authors: | Song, X, Feng, Y, Zhao, Z, Liu, Y. | | Deposit date: | 2018-09-28 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.942 Å) | | Cite: | Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
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6IH6
 | | Phosphite Dehydrogenase mutant I151R/P176R/M207A from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide | | Descriptor: | Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | Authors: | Song, X, Feng, Y, Liu, Y, Zhao, Z. | | Deposit date: | 2018-09-28 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.491 Å) | | Cite: | Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
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6IH8
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1Z2F
 | | solution structure of CfAFP-501 | | Descriptor: | Antifreeze Protein Isoform 501 | | Authors: | Li, C, Jin, C. | | Deposit date: | 2005-03-08 | | Release date: | 2005-10-11 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of an Antifreeze Protein CfAFP-501 from Choristoneura fumiferana
J.Biomol.Nmr, 32, 2005
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7KH1
 | | Baseplate Complex for Myoviridae Phage XM1 | | Descriptor: | baseplate organization protein, gp11, baseplate stabilizing protein, ... | | Authors: | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | Deposit date: | 2020-10-19 | | Release date: | 2021-10-27 | | Last modified: | 2022-05-25 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7JS6
 | | Solution NMR structure of des-citrulassin F | | Descriptor: | des-citrulassin F | | Authors: | Harris, L.A, Mitchell, D.A. | | Deposit date: | 2020-08-13 | | Release date: | 2020-12-16 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Reactivity-Based Screening for Citrulline-Containing Natural Products Reveals a Family of Bacterial Peptidyl Arginine Deiminases.
Acs Chem.Biol., 15, 2020
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7KLN
 | | Myoviridae Phage XM1 Neck Region (12-fold) | | Descriptor: | Head completion protein, gp1, Portal protein | | Authors: | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | Deposit date: | 2020-10-30 | | Release date: | 2021-11-03 | | Last modified: | 2022-05-25 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KJK
 | | The Neck region of Phage XM1 (6-fold symmetry) | | Descriptor: | Collar spike protein, Head completion protein, Tail sheath protein, ... | | Authors: | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | Deposit date: | 2020-10-26 | | Release date: | 2021-11-03 | | Last modified: | 2022-05-25 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KMX
 | | The capsid of Myoviridae Phage XM1 | | Descriptor: | Major capsid protein, Minor capsid protein | | Authors: | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | Deposit date: | 2020-11-03 | | Release date: | 2021-11-10 | | Last modified: | 2022-05-25 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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