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4I0P
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BU of 4i0p by Molmil
HLA-DO in complex with HLA-DM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ...
著者Guce, A.I, Mortimer, S.E, Stern, L.J.
登録日2012-11-18
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism.
Nat.Struct.Mol.Biol., 20, 2013
3S5Y
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BU of 3s5y by Molmil
Pharmacological Chaperoning in Human alpha-Galactosidase
分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guce, A.I, Clark, N.E, Garman, S.C.
登録日2011-05-23
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献The molecular basis of pharmacological chaperoning in human alpha-galactosidase
Chem.Biol., 18, 2011
3S5Z
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Pharmacological Chaperoning in Human alpha-Galactosidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ...
著者Guce, A.I, Clark, N.E, Garman, S.C.
登録日2011-05-23
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献The molecular basis of pharmacological chaperoning in human alpha-galactosidase
Chem.Biol., 18, 2011
3HG4
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Human alpha-galactosidase catalytic mechanism 3. Covalent intermediate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guce, A.I, Clark, N.E, Garman, S.C.
登録日2009-05-13
公開日2009-11-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Catalytic mechanism of human alpha-galactosidase.
J.Biol.Chem., 285, 2010
3HG5
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BU of 3hg5 by Molmil
Human alpha-galactosidase catalytic mechanism 4. Product bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, Alpha-galactosidase A, ...
著者Guce, A.I, Clark, N.E, Garman, S.C.
登録日2009-05-13
公開日2009-11-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Catalytic mechanism of human alpha-galactosidase.
J.Biol.Chem., 285, 2010
3HG2
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BU of 3hg2 by Molmil
Human alpha-galactosidase catalytic mechanism 1. Empty active site
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, Alpha-galactosidase A, ...
著者Guce, A.I, Clark, N.E, Garman, S.C.
登録日2009-05-13
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Catalytic mechanism of human alpha-galactosidase.
J.Biol.Chem., 285, 2010
3HG3
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BU of 3hg3 by Molmil
Human alpha-galactosidase catalytic mechanism 2. Substrate bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Guce, A.I, Clark, N.E, Garman, S.C.
登録日2009-05-13
公開日2009-11-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Catalytic mechanism of human alpha-galactosidase.
J.Biol.Chem., 285, 2010
4NCQ
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BU of 4ncq by Molmil
Crystal structure of NiSOD H1A mutant
分子名称: Superoxide dismutase [Ni]
著者Guce, A.I, Garman, S.C.
登録日2013-10-24
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Nickel superoxide dismutase: structural and functional roles of His1 and its H-bonding network.
Biochemistry, 54, 2015
3TV8
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BU of 3tv8 by Molmil
Pharmacological Chaperoning in Human alpha-Galactosidase
分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Rogich, J.J, Guce, A.I, Clark, N.E, Garman, S.C.
登録日2011-09-19
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.639 Å)
主引用文献The molecular basis of pharmacological chaperoning in human alpha-galactosidase
Chem.Biol., 18, 2011
3LX9
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BU of 3lx9 by Molmil
Interconversion of Human Lysosomal Enzyme Specificities
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C.
登録日2010-02-25
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases.
J.Biol.Chem., 285, 2010
3LXA
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BU of 3lxa by Molmil
Interconversion of Human Lysosomal Enzyme Specificities
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C.
登録日2010-02-25
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases.
J.Biol.Chem., 285, 2010
3LXC
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BU of 3lxc by Molmil
Interconversion of Human Lysosomal Enzyme Specificities
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ...
著者Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C.
登録日2010-02-25
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases.
J.Biol.Chem., 285, 2010
3LXB
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BU of 3lxb by Molmil
Interconversion of Human Lysosomal Enzyme Specificities
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C.
登録日2010-02-25
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases.
J.Biol.Chem., 285, 2010
3G4X
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BU of 3g4x by Molmil
Crystal Structure of NiSOD Y9F mutant
分子名称: CHLORIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni]
著者Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J.
登録日2009-02-04
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009
3G4Z
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Crystal Structure of NiSOD Y9F mutant at 1.9 A
分子名称: BROMIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni]
著者Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J.
登録日2009-02-04
公開日2009-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009
3G50
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BU of 3g50 by Molmil
Crystal Structure of NiSOD D3A mutant at 1.9 A
分子名称: NICKEL (II) ION, Superoxide dismutase [Ni]
著者Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J.
登録日2009-02-04
公開日2009-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009

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