4V9R
 
 | | Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | | 著者 | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | | 登録日 | 2013-12-05 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
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4V9S
 | | Crystal structure of antibiotic GE82832 bound to 70S ribosome | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | | 著者 | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | | 登録日 | 2013-12-05 | | 公開日 | 2014-07-09 | | 最終更新日 | 2018-06-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
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1Z9B
 | | Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2 | | 分子名称: | Translation initiation factor IF-2 | | 著者 | Wienk, H, Tomaselli, S, Bernard, C, Spurio, R, Picone, D, Gualerzi, C.O, Boelens, R. | | 登録日 | 2005-04-01 | | 公開日 | 2005-08-30 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2
Protein Sci., 14, 2005
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1AH9
 | | THE STRUCTURE OF THE TRANSLATIONAL INITIATION FACTOR IF1 FROM ESCHERICHIA COLI, NMR, 19 STRUCTURES | | 分子名称: | INITIATION FACTOR 1 | | 著者 | Sette, M, Van Tilborg, P, Spurio, R, Kaptein, R, Paci, M, Gualerzi, C.O, Boelens, R. | | 登録日 | 1997-04-16 | | 公開日 | 1997-07-07 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif.
EMBO J., 16, 1997
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2NBG
 | | Structure of the Geobacillus stearothermophilus IF2 G3-subdomain | | 分子名称: | Translation initiation factor IF-2 | | 著者 | Dongre, R, Folkers, G.E, Gualerzi, C.O, Boelens, R, Wienk, H. | | 登録日 | 2016-02-11 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A model for the interaction of the G3-subdomain of Geobacillus stearothermophilus IF2 with the 30S ribosomal subunit.
Protein Sci., 25, 2016
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2LKC
 | | Free B.st IF2-G2 | | 分子名称: | Translation initiation factor IF-2 | | 著者 | Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R. | | 登録日 | 2011-10-10 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Dynamics of Bacterial Translation Initiation Factor IF2.
J.Biol.Chem., 287, 2012
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2LKD
 | | IF2-G2 GDP complex | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2 | | 著者 | Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R. | | 登録日 | 2011-10-10 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Dynamics of Bacterial Translation Initiation Factor IF2.
J.Biol.Chem., 287, 2012
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3J4J
 | | Model of full-length T. thermophilus Translation Initiation Factor 2 refined against its cryo-EM density from a 30S Initiation Complex map | | 分子名称: | Translation initiation factor IF-2 | | 著者 | Simonetti, A, Marzi, S, Billas, I.M.L, Tsai, A, Fabbretti, A, Myasnikov, A, Roblin, P, Vaiana, A.C, Hazemann, I, Eiler, D, Steitz, T.A, Puglisi, J.D, Gualerzi, C.O, Klaholz, B.P. | | 登録日 | 2013-08-26 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | | 主引用文献 | Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5ME0
 | | Structure of the 30S Pre-Initiation Complex 1 (30S IC-1) Stalled by GE81112 | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | | 登録日 | 2016-11-14 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | | 主引用文献 | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
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5ME1
 | | Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112 | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | | 登録日 | 2016-11-14 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | | 主引用文献 | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
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5IWA
 | | Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic | | 分子名称: | (2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acid, 16S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Chieko, N, Masahito, K, Takemoto, C, Yokoyama, S, Connell, S.R, Fucini, P. | | 登録日 | 2016-03-22 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1D1N
 | | SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2 | | 分子名称: | INITIATION FACTOR 2 | | 著者 | Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M. | | 登録日 | 1999-09-20 | | 公開日 | 2000-09-20 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
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4B3X
 | | Bacterial translation initiation factor IF2 (1-363), apo form | | 分子名称: | GLYCEROL, TRANSLATION INITIATION FACTOR IF-2 | | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | | 登録日 | 2012-07-26 | | 公開日 | 2013-05-29 | | 最終更新日 | 2013-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
Acta Crystallogr.,Sect.D, 69, 2013
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4B43
 | | Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A | | 分子名称: | GLYCEROL, IODIDE ION, MAGNESIUM ION, ... | | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | | 登録日 | 2012-07-27 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.937 Å) | | 主引用文献 | Molecular Basis of GTP Hydrolysis by Bacterial Translation Initiation Factor If2
To be Published
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4B44
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4B47
 | | Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2 | | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | | 登録日 | 2012-07-27 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
Acta Crystallogr.,Sect.D, 69, 2013
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4B48
 | | Bacterial translation initiation factor IF2 (1-363), complex with GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2 | | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | | 登録日 | 2012-07-27 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
Acta Crystallogr.,Sect.D, 69, 2013
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5DM6
 | | Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | | 著者 | Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. | | 登録日 | 2015-09-08 | | 公開日 | 2015-11-11 | | 最終更新日 | 2016-02-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
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5DM7
 | | Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | | 著者 | Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. | | 登録日 | 2015-09-08 | | 公開日 | 2015-11-11 | | 最終更新日 | 2015-11-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
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