8DS8
 
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4QGU
 | | protein domain complex with ssDNA | | Descriptor: | DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3'), Gamma-interferon-inducible protein 16 | | Authors: | Ni, X, Ru, H, Zhao, L, Shaw, N, Ding, W, Songying, O, Liu, Z.-J. | | Deposit date: | 2014-05-25 | | Release date: | 2015-06-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.545 Å) | | Cite: | New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
J Mol Cell Biol, 8, 2016
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2B1N
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6VIL
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2AFV
 | | The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis | | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | | Authors: | Xue, Y, Wei, Z. | | Deposit date: | 2005-07-26 | | Release date: | 2006-04-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis
J.Struct.Biol., 153, 2006
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2AFR
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2B1M
 | | Crystal structure of a papain-fold protein without the catalytic cysteine from seeds of Pachyrhizus erosus | | Descriptor: | DI(HYDROXYETHYL)ETHER, SPE31, TETRAETHYLENE GLYCOL, ... | | Authors: | Zhang, M, Wei, Z, Chang, S. | | Deposit date: | 2005-09-16 | | Release date: | 2006-10-03 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family
J.Mol.Biol., 358, 2006
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7XHF
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7XHG
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8TVP
 | | Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) | | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVV
 | | Cryo-EM structure of backtracked Pol II | | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVY
 | | Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVQ
 | | Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26 | | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVX
 | | Cryo-EM structure of CPD-stalled Pol II (Conformation 2) | | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVW
 | | Cryo-EM structure of CPD-stalled Pol II (conformation 1) | | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVS
 | | Cryo-EM structure of backtracked Pol II in complex with Rad26 | | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TUG
 | | Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) | | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-16 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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3L6A
 | | Crystal structure of the C-terminal region of Human p97 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Eukaryotic translation initiation factor 4 gamma 2, ... | | Authors: | Fan, S. | | Deposit date: | 2009-12-23 | | Release date: | 2010-04-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the C-terminal region of human p97/DAP5.
Proteins, 78, 2010
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2ZND
 | | Crystal structure of Ca2+-free form of des3-20ALG-2 | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, PHOSPHATE ION, Programmed cell death protein 6, ... | | Authors: | Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M. | | Deposit date: | 2008-04-22 | | Release date: | 2008-09-09 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
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2N51
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2MVM
 | | Solution structure of eEF1Bdelta CAR domain | | Descriptor: | Elongation factor 1-delta | | Authors: | Wu, H, Feng, Y. | | Deposit date: | 2014-10-09 | | Release date: | 2015-02-04 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.
J.Biol.Chem., 290, 2015
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2MVN
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4R5Y
 | | The complex structure of Braf V600E kinase domain with a novel Braf inhibitor | | Descriptor: | 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf | | Authors: | Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M. | | Deposit date: | 2014-08-22 | | Release date: | 2016-02-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Mol.Cancer Ther., 14, 2015
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7X98
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1ND1
 | | Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities. | | Descriptor: | BaP1, ZINC ION | | Authors: | Watanabe, L, Shannon, J.D, Valente, R.H, Rucavado, A, Alape-Giron, A, Kamiguti, A.S, Theakston, R.D, Fox, J.W, Gutierrez, J.M, Arni, R.K. | | Deposit date: | 2002-12-06 | | Release date: | 2003-11-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities
Protein Sci., 12, 2003
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