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225D
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BU of 225d by Molmil
A TETRAMERIC DNA STRUCTURE WITH PROTONATED CYTOSINE:CYTOSINE BASE PAIRS
Descriptor: DNA (5'-D(*TP*CP*CP*CP*CP*C)-3')
Authors:Gehring, K, Leroy, J.L, Gueron, M.
Deposit date:1995-07-12
Release date:1995-10-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A tetrameric DNA structure with protonated cytosine.cytosine base pairs.
Nature, 363, 1993
3DF0
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BU of 3df0 by Molmil
Calcium-dependent complex between m-calpain and calpastatin
Descriptor: CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ...
Authors:Moldoveanu, T, Gehring, K, Green, D.R.
Deposit date:2008-06-11
Release date:2008-11-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
Nature, 456, 2008
4G3O
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BU of 4g3o by Molmil
Crystal structure of the CUE domain of the E3 ubiquitin ligase AMFR (gp78)
Descriptor: E3 ubiquitin-protein ligase AMFR
Authors:Kozlov, G, LePage, K, Gehring, K.
Deposit date:2012-07-15
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the CUE domain of the E3 ubiquitin ligase AMFR (gp78)
To be Published
4ZYN
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BU of 4zyn by Molmil
Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130)
Descriptor: E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION
Authors:Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K.
Deposit date:2015-05-21
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:A Ubl/ubiquitin switch in the activation of Parkin.
Embo J., 34, 2015
6DFD
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BU of 6dfd by Molmil
Crystal structure of CNNM3 cyclic nucleotide-binding homology domain
Descriptor: Metal transporter CNNM3
Authors:Kozlov, G, Gehring, K.
Deposit date:2018-05-14
Release date:2018-10-31
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+efflux activity.
J. Biol. Chem., 293, 2018
5VSZ
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BU of 5vsz by Molmil
Structure of the Ubl domain of Sacsin mutant L78M
Descriptor: Sacsin
Authors:Trempe, J.-F, Pande, H, Shenker, S, Gehring, K.
Deposit date:2017-05-15
Release date:2017-05-31
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
5VSX
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BU of 5vsx by Molmil
Structure of the Ubl domain of Sacsin
Descriptor: Sacsin
Authors:Trempe, J.-F, Pande, H, Shenker, S, Gehring, K.
Deposit date:2017-05-13
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
8SMO
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BU of 8smo by Molmil
Crystal structure of the complex between truncated MLLE domain of PABPC1 and engineered superPAM2 peptide
Descriptor: Polyadenylate-binding protein 1, SULFATE ION, superPAM2
Authors:Kozlov, G, Gehring, K.
Deposit date:2023-04-26
Release date:2024-05-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the complex between truncated MLLE domain of PABPC1 and engineered superPAM2 peptide
To Be Published
8GK6
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BU of 8gk6 by Molmil
Crystal structure of extracellular domain of CNNM4 from Echinococcus granulosus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Metal transporter CNNM4, ...
Authors:Shahsavan, A, Gehring, K.
Deposit date:2023-03-17
Release date:2023-12-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of the CNNM extracellular domain.
Protein Sci., 33, 2024
4Z2Z
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BU of 4z2z by Molmil
New crystal structure of yeast Ddi1 aspartyl protease reveals substrate engagement mode
Descriptor: DNA damage-inducible protein 1
Authors:Trempe, J.-F, Feng, X, Gehring, K.
Deposit date:2015-03-30
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
4NWY
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BU of 4nwy by Molmil
Crystal structure of the b' domain of human protein disulfide isomerase-like protein of the testis (PDILT)
Descriptor: FORMIC ACID, Protein disulfide-isomerase-like protein of the testis
Authors:Bastos-Aristizabal, S, Kozlov, G, Gehring, K.
Deposit date:2013-12-07
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the substrate-binding b' domain of the Protein disulfide isomerase-like protein of the testis.
Sci Rep, 4, 2014
6PIK
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BU of 6pik by Molmil
Tetrameric cryo-EM ArnA
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
6PIH
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BU of 6pih by Molmil
Hexameric ArnA cryo-EM structure
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
8G90
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BU of 8g90 by Molmil
LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
8G91
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BU of 8g91 by Molmil
LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
5WD9
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BU of 5wd9 by Molmil
Crystal structure of Legionella pneumophila effector lpg2328
Descriptor: Lem22
Authors:Kozlov, G, Wong, K, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2017-07-04
Release date:2017-11-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the Legionella effector Lem22.
Proteins, 86, 2018
5WD8
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BU of 5wd8 by Molmil
Crystal structure of Legionella pneumophila effector lpg2328
Descriptor: Lem22
Authors:Kozlov, G, Wong, K, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2017-07-04
Release date:2017-11-29
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:Crystal structure of the Legionella effector Lem22.
Proteins, 86, 2018
8CT8
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BU of 8ct8 by Molmil
Crystal structure of Drosophila melanogaster PRL/CBS-pair domain complex
Descriptor: IODIDE ION, PRL-1 phosphatase, Unextended protein
Authors:Fakih, R, Goldstein, R.H, Kozlov, G, Gehring, K.
Deposit date:2022-05-13
Release date:2023-03-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver.
J.Biol.Chem., 299, 2023
8F6D
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BU of 8f6d by Molmil
Crystal structure of the CNNM2 CBS-pair domain in complex with ARL15
Descriptor: ADP-ribosylation factor-like protein 15, Metal transporter CNNM2
Authors:Kozlov, G, Mahbub, L, Gehring, K.
Deposit date:2022-11-16
Release date:2023-07-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15.
Elife, 12, 2023
8EY8
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BU of 8ey8 by Molmil
LaM domain of human LARP1 in complex with AAAAGA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*GP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2022-10-26
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural insights into poly(A) tail stabilization via 3'-end guanylation
To Be Published
8EY6
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BU of 8ey6 by Molmil
LaM domain of human LARP1 in complex with AAAAAG RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*G)-3'), SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2022-10-26
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural insights into poly(A) tail stabilization via 3'-end guanylation
To Be Published
8EY7
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BU of 8ey7 by Molmil
LaM domain of human LARP1 in complex with AAAGAA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*GP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2022-10-26
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into poly(A) tail stabilization via 3'-end guanylation
To Be Published
2X5N
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BU of 2x5n by Molmil
Crystal Structure of the SpRpn10 VWA domain
Descriptor: 26S PROTEASOME REGULATORY SUBUNIT RPN10, SULFATE ION
Authors:Riedinger, C, Boehringer, J, Trempe, J.-F, Lowe, E.D, Brown, N.R, Gehring, K, Noble, M.E.M, Gordon, C, Endicott, J.A.
Deposit date:2010-02-10
Release date:2010-08-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Structure of Rpn10 and its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12.
J.Biol.Chem., 285, 2010
3BCY
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BU of 3bcy by Molmil
Crystal structure of YER067W
Descriptor: Protein YER067W
Authors:Kozlov, G, Gehring, K.
Deposit date:2007-11-13
Release date:2008-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional study of YER067W, a new protein involved in yeast metabolism control and drug resistance.
Plos One, 5, 2010
3BXY
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BU of 3bxy by Molmil
Crystal structure of tetrahydrodipicolinate N-succinyltransferase from E. coli
Descriptor: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Authors:Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2008-01-15
Release date:2008-01-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding.
Febs Lett., 582, 2008

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