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1B9Y
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA
分子名称: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN)
著者Gaudet, R, Sigler, P.B.
登録日1999-02-16
公開日1999-02-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1B9X
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BU of 1b9x by Molmil
STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN
分子名称: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN)
著者Gaudet, R, Sigler, P.B.
登録日1999-02-16
公開日1999-02-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1JJ7
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BU of 1jj7 by Molmil
Crystal Structure of the C-terminal ATPase domain of human TAP1
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PEPTIDE TRANSPORTER TAP1
著者Gaudet, R, Wiley, D.C.
登録日2001-07-03
公開日2001-09-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.
EMBO J., 20, 2001
2TRC
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BU of 2trc by Molmil
PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
分子名称: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN
著者Gaudet, R, Bohm, A, Sigler, P.B.
登録日1997-01-06
公開日1997-06-05
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
6D9W
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BU of 6d9w by Molmil
Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter, in the inward-open apo state
分子名称: Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ...
著者Gaudet, R, Bane, L.B, Weihofen, W.A, Singharoy, A, Zimanyi, C.M, Bozzi, A.T.
登録日2018-04-30
公開日2019-02-13
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.941 Å)
主引用文献Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter.
Elife, 8, 2019
6ORR
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BU of 6orr by Molmil
Co-crystal structure of human NicotinamideN-Methyltransferase (NNMT) in complex with High-Affinity Alkynyl Bisubstrate Inhibitor NS1
分子名称: 9-{9-amino-6-[(3-carbamoylphenyl)ethynyl]-5,6,7,8,9-pentadeoxy-D-glycero-alpha-L-talo-decofuranuronosyl}-9H-purin-6-amine, GLYCEROL, NNMT protein
著者May, E.J, Policarpo, R.L, Gaudet, R.
登録日2019-04-30
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献High-Affinity Alkynyl Bisubstrate Inhibitors of NicotinamideN-Methyltransferase (NNMT).
J.Med.Chem., 62, 2019
7UL6
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BU of 7ul6 by Molmil
CryoEM structure of full-length dimeric ClbP
分子名称: Beta-lactamase
著者Velilla, J.A, Walsh Jr, R.M, Gaudet, R.
登録日2022-04-04
公開日2022-09-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Structural basis of colibactin activation by the ClbP peptidase.
Nat.Chem.Biol., 19, 2023
8VC2
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CryoEM structure of insect gustatory receptor BmGr9 in the presence of fructose
分子名称: (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, Gustatory receptor
著者Frank, H.M, Walsh Jr, R.M, Garrity, P.A, Gaudet, R.
登録日2023-12-13
公開日2024-01-10
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Structure of an insect gustatory receptor.
Biorxiv, 2023
8VC1
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CryoEM structure of insect gustatory receptor BmGr9
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, ...
著者Frank, H.M, Walsh Jr, R.M, Garrity, P.A, Gaudet, R.
登録日2023-12-13
公開日2024-01-10
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structure of an insect gustatory receptor.
Biorxiv, 2023
4K8O
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BU of 4k8o by Molmil
CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Antigen peptide transporter 1, CITRIC ACID, ...
著者Vakkasoglu, A.S, Grossmann, N, Hulpke, S, Abele, R, Tampe, R, Gaudet, R.
登録日2013-04-18
公開日2014-09-03
最終更新日2014-12-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
Nat Commun, 5, 2014
7MDE
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BU of 7mde by Molmil
Full-length S95A ClbP
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Beta-lactamase, CHLORIDE ION, ...
著者Velilla, J.A, Volpe, M.R, Gaudet, R.
登録日2021-04-04
公開日2022-09-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of colibactin activation by the ClbP peptidase.
Nat.Chem.Biol., 19, 2023
7MDC
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BU of 7mdc by Molmil
Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ...
著者Velilla, J.A, Volpe, M.R, Gaudet, R.
登録日2021-04-03
公開日2022-09-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A small molecule inhibitor prevents gut bacterial genotoxin production.
Nat.Chem.Biol., 19, 2023
7MDF
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BU of 7mdf by Molmil
Full-length S95A ClbP bound to N-acyl-D-asparagine analog
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ...
著者Velilla, J.A, Volpe, M.R, Gaudet, R.
登録日2021-04-04
公開日2022-09-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of colibactin activation by the ClbP peptidase.
Nat.Chem.Biol., 19, 2023
6C3I
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BU of 6c3i by Molmil
Crystal structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter G45R mutant in an inward occluded state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Divalent metal cation transporter MntH
著者Zimanyi, C.M, Bozzi, A.T, Gaudet, R.
登録日2018-01-09
公開日2019-02-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95012617 Å)
主引用文献Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter.
Elife, 8, 2019
3JXJ
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BU of 3jxj by Molmil
Crystal structure of the chicken TRPV4 ankyrin repeat domain
分子名称: PHOSPHATE ION, Vanilloid receptor-related osmotically activated channel protein
著者Phelps, C.B, Choo, S.S, Gaudet, R.
登録日2009-09-19
公開日2009-12-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.
Nat.Genet., 42, 2010
3JXI
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BU of 3jxi by Molmil
Crystal structure of the chicken TRPV4 ankyrin repeat domain
分子名称: Vanilloid receptor-related osmotically activated channel protein
著者Phelps, C.B, Wang, R.R, Gaudet, R.
登録日2009-09-19
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.
Nat.Genet., 42, 2010
3SUI
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BU of 3sui by Molmil
Crystal structure of ca2+-calmodulin in complex with a trpv1 c-terminal peptide
分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ...
著者Lau, S.-Y, Gaudet, R.
登録日2011-07-11
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel.
J.Gen.Physiol., 140, 2012
5UCG
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BU of 5ucg by Molmil
Structure of the PP2C Phosphatase Domain and a Fragment of the Regulatory Domain of the Cell Fate Determinant SpoIIE from Bacillus Subtilis
分子名称: Stage II sporulation protein E
著者Bradshaw, N, Levdikov, V, Zimanyi, C, Gaudet, R, Wilkinson, A, Losick, R.
登録日2016-12-22
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.906 Å)
主引用文献A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
4ZI9
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BU of 4zi9 by Molmil
Structure of mouse clustered PcdhgA1 EC1-3
分子名称: CALCIUM ION, MCG133388, isoform CRA_t
著者Nicoludis, J.M, Lau, S.-Y, Scharfe, C.P.I, Marks, D.S, Weihofen, W.A, Gaudet, R.
登録日2015-04-27
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity.
Structure, 23, 2015
4ZI8
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Structure of mouse clustered PcdhgC3 EC1-3
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Nicoludis, J.M, Lau, S.-Y, Scharfe, C.P.I, Marks, D.S, Weihofen, W.A, Gaudet, R.
登録日2015-04-27
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity.
Structure, 23, 2015
1XD3
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BU of 1xd3 by Molmil
Crystal structure of UCHL3-UbVME complex
分子名称: MAGNESIUM ION, METHYL 4-AMINOBUTANOATE, UBC protein, ...
著者Misaghi, S, Galardy, P.J, Meester, W.J.N, Ovaa, H, Ploegh, H.L, Gaudet, R.
登録日2004-09-03
公開日2004-11-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J.Biol.Chem., 280, 2005
8E5S
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BU of 8e5s by Molmil
X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter WT in an occluded state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ray, S, Gaudet, R.
登録日2022-08-22
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter.
Elife, 12, 2023
8E60
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X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter WT in an occluded, manganese-bound state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ray, S, Gaudet, R.
登録日2022-08-22
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter.
Elife, 12, 2023
8E6I
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X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter M230A mutant in an inward-open, manganese-bound state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ray, S, Gaudet, R.
登録日2022-08-22
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter.
Elife, 12, 2023
8E5V
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X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter WTsoak in an occluded state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ray, S, Gaudet, R.
登録日2022-08-22
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter.
Elife, 12, 2023

 

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