3JXI

Crystal structure of the chicken TRPV4 ankyrin repeat domain

Summary for 3JXI

Entry DOI	10.2210/pdb3jxi/pdb
Related	2etb 2pnn 2rfa 3JZJ
Descriptor	Vanilloid receptor-related osmotically activated channel protein (2 entities in total)
Functional Keywords	ankyrin repeats, ank repeat, ion transport, ionic channel, receptor, transmembrane, transport, membrane protein
Biological source	Gallus gallus (chicken)
Total number of polymer chains	4
Total formula weight	117915.56
Authors	Phelps, C.B.,Wang, R.R.,Gaudet, R. (deposition date: 2009-09-19, release date: 2009-12-22, Last modification date: 2023-09-06)
Primary citation	Landoure, G.,Zdebik, A.A.,Martinez, T.L.,Burnett, B.G.,Stanescu, H.C.,Inada, H.,Shi, Y.,Taye, A.A.,Kong, L.,Munns, C.H.,Choo, S.S.,Phelps, C.B.,Paudel, R.,Houlden, H.,Ludlow, C.L.,Caterina, M.J.,Gaudet, R.,Kleta, R.,Fischbeck, K.H.,Sumner, C.J. Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C. Nat.Genet., 42:170-174, 2010 Cited by PubMed: 20037586 DOI: 10.1038/ng.512 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation