7ZTK
| NME1 in complex with CoA | Descriptor: | COENZYME A, Nucleoside diphosphate kinase A | Authors: | Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C. | Deposit date: | 2022-05-10 | Release date: | 2023-08-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet. Sci Adv, 9, 2023
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2GLR
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2E9S
| human neuronal Rab6B in three intermediate forms | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NITRATE ION, ... | Authors: | Vellieux, F.M, Tcherniuk, S, Garcia-Saez, I, Kozielski, F. | Deposit date: | 2007-01-26 | Release date: | 2008-01-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | 3D structure of human neuronal Rab6B in three intermediate forms To be Published
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1GSY
| GLUTATHIONE S-TRANSFERASE YFYF, CLASS PI, COMPLEXED WITH GLUTATHIONE | Descriptor: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE CLASS PI | Authors: | Parraga, A, Garcia-Saez, I, Coll, M. | Deposit date: | 1996-10-25 | Release date: | 1997-11-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | The three-dimensional structure of a class-Pi glutathione S-transferase complexed with glutathione: the active-site hydration provides insights into the reaction mechanism. Biochem.J., 333 ( Pt 3), 1998
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3PYM
| Structure of GAPDH 3 from S.cerevisiae at 2.0 A resolution | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase 3, MESO-ERYTHRITOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Garcia-Saez, I, Kozielski, F, Job, D, Boscheron, C. | Deposit date: | 2010-12-13 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: |
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2QDS
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1X8I
| Crystal Structure of the Zinc Carbapenemase CphA in Complex with the Antibiotic Biapenem | Descriptor: | 5H-PYRAZOLO(1,2-A)(1,2,4)TRIAZOL-4-IUM, 6-((2-CARBOXY-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-EN-3-YL)THIO)-6,7-DIHYDRO-, HYDROXIDE, ... | Authors: | Garau, G, Dideberg, O. | Deposit date: | 2004-08-18 | Release date: | 2004-12-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Metallo-beta-lactamase Enzyme in Action: Crystal Structures of the Monozinc Carbapenemase CphA and its Complex with Biapenem J.Mol.Biol., 345, 2005
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1X8G
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5DPX
| 1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases. | Descriptor: | 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, Metallo-beta-lactamase L1 type 3, SULFATE ION, ... | Authors: | Nauton, L, Garau, G, Khan, R, Dideberg, O. | Deposit date: | 2015-09-14 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases. ChemMedChem, 12, 2017
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264D
| THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR-GROOVE-BINDING DRUG HOECHST 33258 | Descriptor: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3') | Authors: | Vega, M.C, Garcia-Saez, I, Aymami, J, Eritja, R, Van Der Marel, G.A, Van Boom, J.H, Rich, A, Coll, M. | Deposit date: | 1994-09-22 | Release date: | 1995-03-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258. Eur.J.Biochem., 222, 1994
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1BAY
| GLUTATHIONE S-TRANSFERASE YFYF CYS 47-CARBOXYMETHYLATED CLASS PI, FREE ENZYME | Descriptor: | GLUTATHIONE S-TRANSFERASE CLASS PI | Authors: | Vega, M.C, Coll, M. | Deposit date: | 1996-11-02 | Release date: | 1997-11-12 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region. J.Biol.Chem., 273, 1998
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1GNE
| THE THREE-DIMENSIONAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE OF SCHISTOSOMA JAPONICUM FUSED WITH A CONSERVED NEUTRALIZING EPITOPE ON GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | Descriptor: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | Authors: | Lim, K, Ho, J.X, Keeling, K, Gilliland, G.L, Ji, X, Ruker, F, Carter, D.C. | Deposit date: | 1994-06-16 | Release date: | 1994-11-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV. Protein Sci., 3, 1994
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1X8H
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2GFK
| Crystal structure of the zinc-beta-lactamase l1 from stenotrophomonas maltophilia (inhibitor 2) | Descriptor: | 2,5-DIPHENYLFURAN-3,4-DICARBOXYLIC ACID, DI(HYDROXYETHYL)ETHER, Metallo-beta-lactamase L1, ... | Authors: | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | Deposit date: | 2006-03-22 | Release date: | 2007-03-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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2GKL
| Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate | Descriptor: | Beta-lactamase, GLYCEROL, PYRIDINE-2,4-DICARBOXYLIC ACID, ... | Authors: | Garau, G, Dideberg, O. | Deposit date: | 2006-04-03 | Release date: | 2007-03-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Competitive Inhibitors of the CphA Metallo-{beta}-Lactamase from Aeromonas hydrophila Antimicrob.Agents Chemother., 51, 2007
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2HB9
| Crystal Structure of the Zinc-Beta-Lactamase L1 from Stenotrophomonas Maltophilia (Inhibitor 3) | Descriptor: | 4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE, Metallo-beta-lactamase L1, SULFATE ION, ... | Authors: | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | Deposit date: | 2006-06-14 | Release date: | 2007-05-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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2GFJ
| Crystal structure of the zinc-beta-lactamase L1 from stenotrophomonas maltophilia (inhibitor 1) | Descriptor: | 1,3-DIPHENYL-1H-PYRAZOLE-4,5-DICARBOXYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ... | Authors: | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | Deposit date: | 2006-03-22 | Release date: | 2007-03-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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1GTI
| MODIFIED GLUTATHIONE S-TRANSFERASE (PI) COMPLEXED WITH S (P-NITROBENZYL)GLUTATHIONE | Descriptor: | GLUTATHIONE S-TRANSFERASE, S-(P-NITROBENZYL)GLUTATHIONE | Authors: | Vega, M.C, Coll, M. | Deposit date: | 1998-01-09 | Release date: | 1999-03-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region. J.Biol.Chem., 273, 1998
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