2QDS
Crystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril
Summary for 2QDS
Entry DOI | 10.2210/pdb2qds/pdb |
Related | 1X8G 1X8I 2GKL |
Descriptor | Beta-lactamase, ZINC ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase, lactamase, inhibitor, zn |
Biological source | Aeromonas hydrophila |
Cellular location | Periplasm (Probable): P26918 |
Total number of polymer chains | 1 |
Total formula weight | 26071.95 |
Authors | Garau, G.,Dideberg, O. (deposition date: 2007-06-21, release date: 2007-07-17, Last modification date: 2023-08-30) |
Primary citation | Lienard, B.M.,Garau, G.,Horsfall, L.,Karsisiotis, A.I.,Damblon, C.,Lassaux, P.,Papamicael, C.,Roberts, G.C.,Galleni, M.,Dideberg, O.,Frere, J.M.,Schofield, C.J. Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. Org.Biomol.Chem., 6:2282-2294, 2008 Cited by PubMed: 18563261DOI: 10.1039/b802311e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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