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6OY9
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BU of 6oy9 by Molmil
Structure of the Rhodopsin-Transducin Complex
Descriptor: Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ...
Authors:Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G.
Deposit date:2019-05-14
Release date:2019-07-24
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Mol.Cell, 75, 2019
8QQK
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BU of 8qqk by Molmil
Cryo-EM structure of E. coli cytochrome bo3 quinol oxidase assembled in peptidiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, ...
Authors:Gao, Y, Zhang, Y, Hakke, S, Peters, P.J, Ravelli, R.B.G.
Deposit date:2023-10-05
Release date:2024-04-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of cytochrome bo 3 quinol oxidase assembled in peptidiscs reveals an "open" conformation for potential ubiquinone-8 release.
Biochim Biophys Acta Bioenerg, 1865, 2024
6PZQ
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BU of 6pzq by Molmil
Structure of the human respiratory syncytial virus M2-1 protein in complex with a short positive-sense gene-end RNA
Descriptor: Matrix M2-1, RNA (5'-R(P*GP*UP*UP*AP*AP*U)-3'), ZINC ION
Authors:Gao, Y, Cao, D, Liang, B.
Deposit date:2019-08-01
Release date:2020-08-05
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Structure of the Human Respiratory Syncytial Virus M2-1 Protein in Complex with a Short Positive-Sense Gene-End RNA.
Structure, 28, 2020
7M3G
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BU of 7m3g by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3J
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BU of 7m3j by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3F
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BU of 7m3f by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3E
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BU of 7m3e by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
9JAL
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BU of 9jal by Molmil
Cryo-EM structure of MPXV core protease in complex with compound A1
Descriptor: A1ECM-DI8-ALA-ETA, Core protease I7
Authors:Gao, Y, Xie, X, Lan, W, Wang, W, Yang, H.
Deposit date:2024-08-25
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Cryo-EM structure of MPXV core protease in complex with compound A1
To Be Published
9JAN
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BU of 9jan by Molmil
Cryo-EM structure of MPXV protease in complex with compound A4
Descriptor: A1ECL-DI8-ALA-AEM, Core protease I7
Authors:Gao, Y, Xie, X, Lan, W, Wang, W, Yang, H.
Deposit date:2024-08-25
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Cryo-EM structure of MPXV protease in complex with compound A4
To Be Published
9JAM
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BU of 9jam by Molmil
Cryo-EM structure of MPXV core protease in complex with compound A3
Descriptor: A1ECK-DI8-ALA-AEM, Core protease I7
Authors:Gao, Y, Xie, X, Lan, W, Wang, W, Yang, H.
Deposit date:2024-08-25
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM structure of MPXV core protease in complex with compound A3
To Be Published
2DU9
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BU of 2du9 by Molmil
crystal structure of the transcriptional factor from C.glutamicum
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Predicted transcriptional regulators
Authors:Gao, Y, Yao, M, Tanaka, I.
Deposit date:2006-07-20
Release date:2007-07-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The structures of transcription factor CGL2947 from Corynebacterium glutamicum in two crystal forms: A novel homodimer assembling and the implication for effector-binding mode
Protein Sci., 16, 2007
7JSN
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BU of 7jsn by Molmil
Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6
Descriptor: 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gao, Y, Eskici, G, Ramachandran, S, Skiniotis, G, Cerione, R.A.
Deposit date:2020-08-15
Release date:2020-10-21
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.
Mol.Cell, 80, 2020
5KFC
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BU of 5kfc by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 180s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFL
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BU of 5kfl by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 600s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFX
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BU of 5kfx by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 300s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFE
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BU of 5kfe by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 600s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFO
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BU of 5kfo by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 1 mM Mn2+ for 1800s
Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG1
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BU of 5kg1 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 30 degree
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFG
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BU of 5kfg by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 30s
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFR
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BU of 5kfr by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mn2+ for 600s
Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*(AS))-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG4
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BU of 5kg4 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mg2+ for 60s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFK
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BU of 5kfk by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 300s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFU
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BU of 5kfu by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 80s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG6
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BU of 5kg6 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Ca2+ for 60s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFD
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BU of 5kfd by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 300s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016

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