2RDO
| 50S subunit with EF-G(GDPNP) and RRF bound | Descriptor: | 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | Authors: | Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J. | Deposit date: | 2007-09-24 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits. J.Mol.Biol., 374, 2007
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1ZN1
| Coordinates of RRF fitted into Cryo-EM map of the 70S post-termination complex | Descriptor: | 30S ribosomal protein S12, Ribosome recycling factor, ribosomal 16S RNA, ... | Authors: | Gao, N, Zavialov, A.V, Li, W, Sengupta, J, Valle, M, Gursky, R.P, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (14.1 Å) | Cite: | Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol.Cell, 18, 2005
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4A3N
| Crystal Structure of HMG-BOX of Human SOX17 | Descriptor: | TRANSCRIPTION FACTOR SOX-17, ZINC ION | Authors: | Gao, N, Gao, H, Qian, H, Si, S, Xie, Y. | Deposit date: | 2011-10-01 | Release date: | 2011-12-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA. Protein Pept.Lett., 20, 2013
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1ZN0
| Coordinates of RRF and EF-G fitted into Cryo-EM map of the 50S subunit bound with both EF-G (GDPNP) and RRF | Descriptor: | 16S RIBOSOMAL RNA, ELONGATION FACTOR G, Ribosome recycling factor | Authors: | Gao, N, Zavialov, A.V, Li, W, Sengupta, J, Valle, M, Gursky, R.P, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (15.5 Å) | Cite: | Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol.Cell, 18, 2005
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4WF1
| Crystal structure of the E. coli ribosome bound to negamycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. | Deposit date: | 2014-09-11 | Release date: | 2014-11-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
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8IVQ
| Cryo-EM structure of mouse BIRC6, Global map | Descriptor: | Isoform 2 of Baculoviral IAP repeat-containing protein 6 | Authors: | Liu, S, Jiang, T, Bu, F, Zhao, J, Wang, G, Li, N, Gao, N, Qiu, X. | Deposit date: | 2023-03-28 | Release date: | 2024-01-24 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy. Nat Commun, 15, 2024
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5ADY
| Cryo-EM structures of the 50S ribosome subunit bound with HflX | Descriptor: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ... | Authors: | Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N. | Deposit date: | 2015-08-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions Nat.Struct.Mol.Biol., 22, 2015
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7XBK
| Structure and mechanism of a mitochondrial AAA+ disaggregase CLPB | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Isoform 2 of Caseinolytic peptidase B protein homolog, MAGNESIUM ION, ... | Authors: | Wu, D, Liu, Y, Dai, Y, Wang, G, Lu, G, Chen, Y, Li, N, Lin, J, Gao, N. | Deposit date: | 2022-03-21 | Release date: | 2023-01-25 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization. Plos Biol., 21, 2023
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7XC5
| Crystal structure of the ANK domain of CLPB | Descriptor: | Isoform 2 of Caseinolytic peptidase B protein homolog | Authors: | Liu, Y, Wu, D, Lu, G, Gao, N, Lin, J. | Deposit date: | 2022-03-23 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization. Plos Biol., 21, 2023
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5WUA
| Structure of a Pancreatic ATP-sensitive Potassium Channel | Descriptor: | ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1 | Authors: | Li, N, Wu, J.-X, Chen, L, Gao, N. | Deposit date: | 2016-12-16 | Release date: | 2017-01-25 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Structure of a Pancreatic ATP-Sensitive Potassium Channel Cell, 168, 2017
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2YKR
| 30S ribosomal subunit with RsgA bound in the presence of GMPPNP | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Guo, Q, Yuan, Y, Xu, Y, Feng, B, Liu, L, Chen, K, Lei, J, Gao, N. | Deposit date: | 2011-05-30 | Release date: | 2011-08-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy. Proc.Natl.Acad.Sci.USA, 108, 2011
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7XFN
| Structure of nucleosome-DI complex (-55I, Apo state) | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFL
| Structure of nucleosome-AAG complex (A-53I, free state) | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFM
| Structure of nucleosome-AAG complex (A-53I, post-catalytic state) | Descriptor: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFH
| Structure of nucleosome-AAG complex (A-30I, post-catalytic state) | Descriptor: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFC
| Structure of nucleosome-DI complex (-30I, Apo state) | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFI
| Structure of nucleosome-DI complex (-50I, Apo state) | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XNP
| Structure of nucleosome-AAG complex (A-55I, post-catalytic state) | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-29 | Release date: | 2023-05-03 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFJ
| Structure of nucleosome-AAG complex (T-50I, post-catalytic state) | Descriptor: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | Authors: | Zheng, L, Tsai, B, Gao, N. | Deposit date: | 2022-04-01 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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8XGC
| Structure of yeast replisome associated with FACT and histone hexamer, Composite map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... | Authors: | Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y. | Deposit date: | 2023-12-15 | Release date: | 2024-02-14 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Parental histone transfer caught at the replication fork. Nature, 627, 2024
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7Y1Q
| 5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1 | Descriptor: | Isoform 2 of Basigin, Monocarboxylate transporter 1 | Authors: | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | Deposit date: | 2022-06-08 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (5.03 Å) | Cite: | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2 To Be Published
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7Y1B
| 3.2 angstrom cryo-EM structure of extracellular region of mouse Basigin-2 in complex with the Fab fragment of antibody 6E7F1 | Descriptor: | Heavy chain of 6E7F1, Isoform 2 of Basigin, Light chain of 6E7F1 | Authors: | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | Deposit date: | 2022-06-08 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin To Be Published
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5ZQZ
| Structure of human mitochondrial trifunctional protein, tetramer | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | Authors: | Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J. | Deposit date: | 2018-04-20 | Release date: | 2018-06-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of human mitochondrial trifunctional protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ZRV
| Structure of human mitochondrial trifunctional protein, octamer | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | Authors: | Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J. | Deposit date: | 2018-04-25 | Release date: | 2018-06-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Cryo-EM structure of human mitochondrial trifunctional protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ZR1
| Saccharomyces Cerevisiae Origin Recognition Complex Bound to a 72-bp Origin DNA containing ACS and B1 element | Descriptor: | 72bp-oring DNA, ACS305, A-rich, ... | Authors: | Li, N, Lam, W.H, Zhai, Y, Cheng, J, Cheng, E, Zhao, Y, Gao, N, Tye, B.K. | Deposit date: | 2018-04-21 | Release date: | 2018-07-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the origin recognition complex bound to DNA replication origin. Nature, 559, 2018
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