7W6O
 
 | | Crystal structure of a PSH1 in complex with J1K | | 分子名称: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-02 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7W66
 | | Crystal structure of a PSH1 mutant in complex with ligand | | 分子名称: | PSH1, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7FAX
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7FAW
 | | Structure of LW domain from Yeast | | 分子名称: | Transcription elongation factor S-II | | 著者 | Liao, S, Gao, J, Tu, X. | | 登録日 | 2021-07-07 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.438 Å) | | 主引用文献 | Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
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7XGW
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7YJI
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8H41
 | | Crystal structure of a decarboxylase from Trichosporon moniliiforme in complex with o-nitrophenol | | 分子名称: | MAGNESIUM ION, O-NITROPHENOL, Salicylate decarboxylase | | 著者 | Gao, J, Zhao, Y.P, Li, Q, Liu, W.D, Sheng, X. | | 登録日 | 2022-10-09 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A Combined Computational-Experimental Study on the Substrate Binding and Reaction Mechanism of Salicylic Acid Decarboxylase
Catalysts, 12, 2022
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7DL8
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7DMC
 | | Dipyridamole binds to the N-terminal domain of human Hsp90A | | 分子名称: | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, CHLORIDE ION, Heat shock protein HSP 90-alpha, ... | | 著者 | Shi, L, Zhou, C, Zhong, Y, Gao, J, Zhou, H, Zhang, N. | | 登録日 | 2020-12-03 | | 公開日 | 2021-12-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines.
Biochem Pharmacol, 207, 2022
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5YGK
 | | Crystal structure of a synthase from Streptomyces sp. CL190 with dmaspp | | 分子名称: | Cyclolavandulyl diphosphate synthase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION | | 著者 | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2017-09-23 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | | 主引用文献 | Catalytic Role of Conserved Asparagine, Glutamine, Serine, and Tyrosine Residues in Isoprenoid Biosynthesis Enzymes.
Acs Catalysis, 8, 2018
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5YGJ
 | | Crystal structure of a synthase from Streptomyces sp. CL190 | | 分子名称: | Cyclolavandulyl diphosphate synthase | | 著者 | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2017-09-23 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.648 Å) | | 主引用文献 | Catalytic Role of Conserved Asparagine, Glutamine, Serine, and Tyrosine Residues in Isoprenoid Biosynthesis Enzymes.
Acs Catalysis, 8, 2018
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5ZXA
 | | Crystal structure of fibronectin-binding protein Apa mutant from Mycobacterium tuberculosis | | 分子名称: | Alanine and proline-rich secreted protein Apa, GLYCEROL, MERCURY (II) ION | | 著者 | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2018-05-18 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis.
Biochim Biophys Acta Gen Subj, 1863, 2019
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5ZX9
 | | Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis | | 分子名称: | Alanine and proline-rich secreted protein Apa, GLYCEROL | | 著者 | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2018-05-18 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis.
Biochim Biophys Acta Gen Subj, 1863, 2019
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7K3A
 | | Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation B, fusion peptide release | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Gui, M, Gao, J, Xiang, Y. | | 登録日 | 2020-09-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
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7K3B
 | | Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation C, central helices splay | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Gui, M, Gao, J, Xiang, Y. | | 登録日 | 2020-09-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
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7K37
 | | Structure of full-length influenza HA with a head-binding antibody at pH 7.8 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Gui, M, Xiang, Y, Gao, J. | | 登録日 | 2020-09-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
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7K39
 | | Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation A, neutral pH-like | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Gui, M, Gao, J, Xiang, Y. | | 登録日 | 2020-09-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
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1DVJ
 | | CRYSTAL STRUCTURE OF OROTIDINE MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-AZAUMP | | 分子名称: | 6-AZA URIDINE 5'-MONOPHOSPHATE, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE | | 著者 | Wu, N, Mo, Y, Gao, J, Pai, E.F. | | 登録日 | 2000-03-30 | | 公開日 | 2000-04-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Electrostatic stress in catalysis: structure and mechanism of the enzyme orotidine monophosphate decarboxylase.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1DV7
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6PWC
 | | A complex structure of arrestin-2 bound to neurotensin receptor 1 | | 分子名称: | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... | | 著者 | Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K, Gao, X, He, Y, Gao, J, Wang, X, Zhang, Y, Zhou, H, Melcher, K, Jiang, Y, Cong, Y, Zhou, X.E, Yu, X, Xu, H.E. | | 登録日 | 2019-07-22 | | 公開日 | 2019-12-04 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Cell Res., 29, 2019
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1Q5X
 | | Structure of OF RRAA (MENG), a protein inhibitor of RNA processing | | 分子名称: | REGULATOR OF RNASE E ACTIVITY A | | 著者 | Monzingo, A.F, Gao, J, Qiu, J, Georgiou, G, Robertus, J.D. | | 登録日 | 2003-08-11 | | 公開日 | 2003-09-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003
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3MFQ
 | | A Glance into the Metal Binding Specificity of TroA: Where Elaborate Behaviors Occur in the Active Center | | 分子名称: | High-affinity zinc uptake system protein znuA, ZINC ION | | 著者 | Gao, G.F, Zheng, B, Zhang, Q, Gao, J, Han, H, Li, M. | | 登録日 | 2010-04-03 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Insight into the interaction of metal ions with TroA from Streptococcus suis
Plos One, 6, 2011
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1OS5
 | | Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor. | | 分子名称: | 3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE, Hepatitis C virus NS5B RNA polymerase | | 著者 | Love, R.A, Parge, H.E, Yu, X, Hickey, M.J, Diehl, W, Gao, J, Wriggers, H, Ekker, A, Wang, L, Thomson, J.A, Dragovich, P.S, Fuhrman, S.A. | | 登録日 | 2003-03-18 | | 公開日 | 2004-03-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme.
J.Virol., 77, 2003
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3W28
 | | The high-resolution crystal structure of TsXylA, intracellular xylanase from /Thermoanaerobacterium saccharolyticum JW/SL-YS485/: the complex of the E251A mutant with xylotriose | | 分子名称: | Glycoside hydrolase family 10, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose | | 著者 | Han, X, Gao, J, Shang, N, Huang, C.-H, Ko, T.-P, Zhu, Z, Wiegel, J, Shao, W, Guo, R.-T. | | 登録日 | 2012-11-27 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Structural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Proteins, 81, 2013
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3W29
 | | The high-resolution crystal structure of TsXylA, intracellular xylanase from /Thermoanaerobacterium saccharolyticum JW/SL-YS485/: the complex of the E251A mutant with xylotetraose | | 分子名称: | Glycoside hydrolase family 10, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose | | 著者 | Han, X, Gao, J, Shang, N, Huang, C.-H, Ko, T.-P, Zhu, Z, Wiegel, J, Shao, W, Guo, R.-T. | | 登録日 | 2012-11-27 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Structural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Proteins, 81, 2013
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