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1D9N
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BU of 1d9n by Molmil
SOLUTION STRUCTURE OF THE METHYL-CPG-BINDING DOMAIN OF THE METHYLATION-DEPENDENT TRANSCRIPTIONAL REPRESSOR MBD1/PCM1
分子名称: METHYL-CPG-BINDING PROTEIN MBD1
著者Ohki, I, Shimotake, N, Fujita, N, Nakao, M, Shirakawa, M.
登録日1999-10-28
公開日2000-10-28
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1.
EMBO J., 18, 1999
1IG4
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BU of 1ig4 by Molmil
Solution Structure of the Methyl-CpG-Binding Domain of Human MBD1 in Complex with Methylated DNA
分子名称: 5'-D(*GP*TP*AP*TP*CP*(5CM)P*GP*GP*AP*TP*AP*C)-3', Methyl-CpG Binding Protein
著者Ohki, I, Shimotake, N, Fujita, N, Jee, J.-G, Ikegami, T, Nakao, M, Shirakawa, M.
登録日2001-04-17
公開日2001-05-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.
Cell(Cambridge,Mass.), 105, 2001
1COO
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BU of 1coo by Molmil
THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT
分子名称: RNA POLYMERASE ALPHA SUBUNIT
著者Jeon, Y.H, Negishi, T, Shirakawa, M, Yamazaki, T, Fujita, N, Ishihama, A, Kyogoku, Y.
登録日1995-10-09
公開日1996-03-08
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of the activator contact domain of the RNA polymerase alpha subunit.
Science, 270, 1995
3A99
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BU of 3a99 by Molmil
Structure of PIM-1 kinase crystallized in the presence of P27KIP1 Carboxy-terminal peptide
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase pim-1
著者Morishita, D, Takami, M, Yoshikawa, S, Katayama, R, Sato, S, Kukimoto-Niino, M, Umehara, T, Shirouzu, M, Sekimizu, K, Yokoyama, S, Fujita, N.
登録日2009-10-22
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase
J.Biol.Chem., 286, 2011
4MKC
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BU of 4mkc by Molmil
Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378
分子名称: 5-chloro-N~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine, ALK tyrosine kinase receptor, GLYCEROL
著者Lee, C.C, Spraggon, G.
登録日2013-09-04
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.
Cancer Discov, 4, 2014
5GR0
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BU of 5gr0 by Molmil
Crystal structure of branching enzyme D501A mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GQU
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BU of 5gqu by Molmil
Crystal structure of branching enzyme from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model
J. Biol. Chem., 292, 2017
5GR6
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BU of 5gr6 by Molmil
Crystal structure of branching enzyme Y500A/D501A double mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GR3
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BU of 5gr3 by Molmil
Crystal structure of branching enzyme L541A/W655A mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GQV
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BU of 5gqv by Molmil
Crystal structure of branching enzyme from Cyanothece sp. ATCC 51142 in complex with maltohexaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION, ...
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model
J. Biol. Chem., 292, 2017
5GR4
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BU of 5gr4 by Molmil
Crystal structure of branching enzyme L541A mutant from Cyanothece sp. ATCC 51142 in complex with maltoheptaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION, ...
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GR1
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BU of 5gr1 by Molmil
Crystal structure of branching enzyme Y500A/D501A mutant from Cyanothece sp. ATCC 51142 in complex with maltoheptaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION, ...
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GQY
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BU of 5gqy by Molmil
Crystal structure of branching enzyme from Cyanothece sp. ATCC 51142 in complex with maltoheptaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION, ...
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GR2
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BU of 5gr2 by Molmil
Crystal structure of branching enzyme L541A mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GQX
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BU of 5gqx by Molmil
Crystal structure of branching enzyme W610N mutant from Cyanothece sp. ATCC 51142 in complex with maltoheptaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION, ...
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model
J. Biol. Chem., 292, 2017
5GR5
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BU of 5gr5 by Molmil
Crystal structure of branching enzyme W610A mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
5GQW
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BU of 5gqw by Molmil
Crystal structure of branching enzyme W610N mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model
J. Biol. Chem., 292, 2017
5GQZ
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BU of 5gqz by Molmil
Crystal structure of branching enzyme Y500A mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2016-08-08
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for substrate binding and catalysis of branching enzyme from Cyanothece sp. ATCC 51142
To be published
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
分子名称: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-21
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
8H7X
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BU of 8h7x by Molmil
Crystal structure of EGFR T790M/C797S mutant in complex with brigatinib
分子名称: 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, Epidermal growth factor receptor
著者Kukimoto-Niino, M, Shirouzu, M.
登録日2022-10-21
公開日2023-10-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.404 Å)
主引用文献A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.
NPJ Precis Oncol, 8, 2024
6KLF
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BU of 6klf by Molmil
Crystal structure of branching enzyme D434A mutant from Cyanothece sp. ATCC 51142
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
著者Suzuki, R, Suzuki, E.
登録日2019-07-30
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cyanobacterial branching enzymes bind to alpha-glucan via surface binding sites
Arch.Biochem.Biophys., 702, 2021

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