4UZM
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5OXH
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![BU of 5oxh by Molmil](/molmil-images/mine/5oxh) | C-terminally retracted ubiquitin T66V/L67N mutant | Descriptor: | SULFATE ION, Ubiquitin T66V/L67N mutant | Authors: | Gladkova, C, Schubert, A.F, Wagstaff, J.L, Pruneda, J.P, Freund, S.M.V, Komander, D. | Deposit date: | 2017-09-06 | Release date: | 2017-11-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1. EMBO J., 36, 2017
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5OXI
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![BU of 5oxi by Molmil](/molmil-images/mine/5oxi) | C-terminally retracted ubiquitin L67S mutant | Descriptor: | SULFATE ION, Ubiquitin L67S mutant | Authors: | Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D. | Deposit date: | 2017-09-06 | Release date: | 2017-11-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1. EMBO J., 36, 2017
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7OWG
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![BU of 7owg by Molmil](/molmil-images/mine/7owg) | human DEPTOR in a complex with mutant human mTORC1 A1459P | Descriptor: | DEP domain-containing mTOR-interacting protein, Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, ... | Authors: | Heimhalt, M, Berndt, A, Wagstaff, J, Anandapadamanaban, M, Perisic, O, Maslen, S, McLaughlin, S, Yu, W.-H, Masson, G.R, Boland, A, Ni, X, Yamashita, K, Murshudov, G.N, Skehel, M, Freund, S.M, Williams, R.L. | Deposit date: | 2021-06-18 | Release date: | 2021-09-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace. Elife, 10, 2021
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1ZTR
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![BU of 1ztr by Molmil](/molmil-images/mine/1ztr) | Solution structure of Engrailed homeodomain L16A mutant | Descriptor: | Segmentation polarity homeobox protein engrailed | Authors: | Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R. | Deposit date: | 2005-05-27 | Release date: | 2005-10-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of a protein denatured state and folding intermediate. Nature, 437, 2005
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1AB7
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1BTA
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1BTB
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4WZP
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![BU of 4wzp by Molmil](/molmil-images/mine/4wzp) | Ser65 phosphorylated ubiquitin, major conformation | Descriptor: | SULFATE ION, ubiquitin | Authors: | Wauer, T, Wagstaff, J, Freund, S.M.V, Komander, D. | Deposit date: | 2014-11-20 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis. Embo J., 34, 2015
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2L9N
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5LRU
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![BU of 5lru by Molmil](/molmil-images/mine/5lru) | Structure of Cezanne/OTUD7B OTU domain | Descriptor: | OTU domain-containing protein 7B | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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5LRX
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![BU of 5lrx by Molmil](/molmil-images/mine/5lrx) | Structure of A20 OTU domain bound to ubiquitin | Descriptor: | Polyubiquitin-B, Tumor necrosis factor alpha-induced protein 3 | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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5LRW
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![BU of 5lrw by Molmil](/molmil-images/mine/5lrw) | Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin | Descriptor: | GLYCEROL, OTU domain-containing protein 7B, Polyubiquitin-B | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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5LRV
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![BU of 5lrv by Molmil](/molmil-images/mine/5lrv) | Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin | Descriptor: | GLYCEROL, OTU domain-containing protein 7B, PHOSPHATE ION, ... | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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1P7J
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![BU of 1p7j by Molmil](/molmil-images/mine/1p7j) | Crystal structure of engrailed homeodomain mutant K52E | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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1P7I
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![BU of 1p7i by Molmil](/molmil-images/mine/1p7i) | CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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2FEJ
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![BU of 2fej by Molmil](/molmil-images/mine/2fej) | Solution structure of human p53 DNA binding domain. | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Perez-Canadillas, J.M, Tidow, H, Freund, S.M, Rutherford, T.J, Ang, H.C, Fersht, A.R. | Deposit date: | 2005-12-16 | Release date: | 2006-01-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of p53 core domain: Structural basis for its instability Proc.Natl.Acad.Sci.Usa, 103, 2006
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2J5P
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![BU of 2j5p by Molmil](/molmil-images/mine/2j5p) | E. coli FtsK gamma domain | Descriptor: | DNA TRANSLOCASE FTSK | Authors: | Sivanathan, V, Allen, M.D, de Bekker, C, Baker, R, Arciszewska, L, Freund, S.M, Bycroft, M, Lowe, J, Sherratt, D.J. | Deposit date: | 2006-09-19 | Release date: | 2006-10-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Ftsk Gamma Domain Directs Oriented DNA Translocation by Interacting with Kops. Nat.Struct.Mol.Biol., 13, 2006
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2J5O
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![BU of 2j5o by Molmil](/molmil-images/mine/2j5o) | Pseudomonas aeruginosa FtsK gamma domain | Descriptor: | DNA TRANSLOCASE FTSK | Authors: | Sivanathan, V, Allen, M.D, deBekker, C, Baker, R, Arciszewska, L, Freund, S.M, Bycroft, M, Lowe, J, Sherratt, D.J. | Deposit date: | 2006-09-19 | Release date: | 2006-10-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Ftsk Gamma Domain Directs Oriented DNA Translocation by Interacting with Kops. Nat.Struct.Mol.Biol., 13, 2006
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4AE4
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![BU of 4ae4 by Molmil](/molmil-images/mine/4ae4) | The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a novel SOUBA domain | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, POTASSIUM ION, ... | Authors: | Agromayor, M, Soler, N, Caballe, A, Kueck, T, Freund, S.M, Allen, M.D, Bycroft, M, Perisic, O, Ye, Y, McDonald, B, Scheel, H, Hofmann, K, Neil, S.J.D, Martin-Serrano, J, Williams, R.L. | Deposit date: | 2012-01-06 | Release date: | 2012-03-21 | Last modified: | 2018-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure, 20, 2012
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2W2U
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![BU of 2w2u by Molmil](/molmil-images/mine/2w2u) | STRUCTURAL INSIGHT INTO THE INTERACTION BETWEEN ARCHAEAL ESCRT-III AND AAA-ATPASE | Descriptor: | CONSERVED ARCHAEAL PROTEIN, HYPOTHETICAL P60 KATANIN | Authors: | Obita, T, Samson, R.Y, Perisic, O, Freund, S.M, Bell, S.D, Williams, R.L. | Deposit date: | 2008-11-04 | Release date: | 2009-07-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Role for the Escrt System in Cell Division in Archaea. Science, 322, 2008
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4UZX
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![BU of 4uzx by Molmil](/molmil-images/mine/4uzx) | High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1 | Descriptor: | PROTEIN THO1 | Authors: | Jacobsen, J.O.B, Allen, M.D, Freund, S.M.V, Bycroft, M. | Deposit date: | 2014-09-09 | Release date: | 2014-12-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-Resolution NMR Structures of the Domains of Saccharomyces Cerevisiae Tho1. Acta Crystallogr.,Sect.F, 72, 2016
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4UZW
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![BU of 4uzw by Molmil](/molmil-images/mine/4uzw) | High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1 | Descriptor: | PROTEIN THO1 | Authors: | Jacobsen, J.O.B, Allen, M.D, Freund, S.M.V, Bycroft, M. | Deposit date: | 2014-09-09 | Release date: | 2014-12-17 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | High-Resolution NMR Structures of the Domains of Saccharomyces Cerevisiae Tho1. Acta Crystallogr.,Sect.F, 72, 2016
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5AF6
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![BU of 5af6 by Molmil](/molmil-images/mine/5af6) | Structure of Lys33-linked diUb bound to Trabid NZF1 | Descriptor: | TRABID, UBIQUITIN, ZINC ION | Authors: | Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D. | Deposit date: | 2015-01-19 | Release date: | 2015-03-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin. Mol.Cell, 58, 2015
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5AF5
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![BU of 5af5 by Molmil](/molmil-images/mine/5af5) | Structure of Lys33-linked triUb S.G. P 212121 | Descriptor: | POLYUBIQUITIN-C | Authors: | Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D. | Deposit date: | 2015-01-19 | Release date: | 2015-03-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin. Mol.Cell, 58, 2015
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