8AE7
 
 | | The strucuture of Compound 15 bound to CK2alpha | | Descriptor: | 2-[5,6-bis(bromanyl)-1H-indazol-3-yl]ethanenitrile, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Brear, P, De Fusco, C, Atkinson, E, Frances, N, Iegre, J, Venkitaraman, A, Hyvonen, M, Spring, D. | | Deposit date: | 2022-07-12 | | Release date: | 2023-03-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | A fragment-based approach leading to the discovery of inhibitors of CK2 alpha with a novel mechanism of action.
Rsc Med Chem, 13, 2022
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7ZCH
 | | CHMP2A-CHMP3 heterodimer (410 Angstrom diameter) | | Descriptor: | Charged multivesicular body protein 2a, Charged multivesicular body protein 3 | | Authors: | Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W. | | Deposit date: | 2022-03-28 | | Release date: | 2023-01-18 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
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7ZCG
 | | CHMP2A-CHMP3 heterodimer (430 Angstrom diameter) | | Descriptor: | Charged multivesicular body protein 2a, Charged multivesicular body protein 3 | | Authors: | Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W. | | Deposit date: | 2022-03-28 | | Release date: | 2023-01-18 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
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5FPI
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5G4X
 | | The crystal structure of the SHANK3 N-terminus | | Descriptor: | 1,2-ETHANEDIOL, SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 | | Authors: | Zacharchenko, T, Barsukov, I. | | Deposit date: | 2016-05-17 | | Release date: | 2017-01-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.166 Å) | | Cite: | SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
Nat. Cell Biol., 19, 2017
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1M2X
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